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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
50644
World Ranking
994
National Ranking
20

Medicine

D-Index
109
Citations
50641
World Ranking
5717
National Ranking
71

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Kristina Schoonjans is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research focuses primarily on medicine and biochemistry, genetics, and molecular biology, with significant contributions to subfields such as molecular biology, epidemiology, surgery, oncology, and physiology.

The scientist's work covers important topics including liver disease diagnosis and treatment, drug transport and resistance mechanisms, pancreatic function and diabetes, endoplasmic reticulum stress and disease, adipose tissue and metabolism, pediatric hepatobiliary diseases and treatments, and liver physiology and pathology.

Frequent publication venues for Kristina Schoonjans include the Journal of Hepatology, bioRxiv (Cold Spring Harbor Laboratory), eLife, Nature Communications, and Cell Metabolism. These platforms have featured multiple scientific articles co-authored by Schoonjans, reflecting the scope of their research interests.

Recent notable papers are:

  • Molecular physiology of bile acid signaling in health, disease, and aging (2020, Physiological Reviews)
  • Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration (2020, Gastroenterology)
  • Mechano-modulatory synthetic niches for liver organoid derivation (2020, Nature Communications)
  • Hypothalamic bile acid-TGR5 signaling protects from obesity (2021, Cell Metabolism)
  • Metabolic Messengers: bile acids (2022, Nature Metabolism)

Kristina Schoonjans has collaborated frequently with several researchers, including Alessia Perino, Johan Auwerx, Hadrien Demagny, Antoine Jalil, and Maroun Bou Sleiman. These partnerships have contributed to a range of publications and research projects over time.

Best Publications

  • Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

    Mitsuhiro Watanabe;Sander M. Houten;Chikage Mataki;Marcelo A. Christoffolete

  • Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism

    Bart Staels;Jean Dallongeville;Johan Auwerx;Kristina Schoonjans

  • TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

    Charles W. Thomas;Antimo Gioiello;Lilia G Noriega;Lilia G Noriega;Axelle Strehle

  • Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors.

    Timothy T. Lu;Makoto Makishima;Joyce J. Repa;Kristina Schoonjans

  • The organization, promoter analysis, and expression of the human PPARgamma gene.

    Lluis Fajas;Didier Auboeuf;Eric Raspé;Kristina Schoonjans

  • Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression.

    Kristina Schoonjans;Bart Staels;Johan Auwerx

  • Targeting bile-acid signalling for metabolic diseases

    Charles Thomas;Roberto Pellicciari;Mark Pruzanski;Johan Auwerx

  • PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene

    K. Schoonjans;J. Peinado-Onsurbe;A. M. Lefebvre;R. A. Heyman

  • The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation

    Kristina Schoonjans;Bart Staels;Johan Auwerx

  • The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet induced obesity

    Carles Cantó;Riekelt H. Houtkooper;Eija Pirinen;Eija Pirinen;Dou Y. Youn

  • The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

    Laurent Mouchiroud;Riekelt H. Houtkooper;Norman Moullan;Elena Katsyuba

  • NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

    Hongbo Zhang;Dongryeol Ryu;Yibo Wu;Karim Gariani

  • PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

    Péter Bai;Péter Bai;Carles Cantó;Hugues Oudart;Attila Brunyánszki

  • Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

    Sungsoon Fang;Jae Myoung Suh;Shannon M Reilly;Elizabeth Yu

  • Coordinate Regulation of the Expression of the Fatty Acid Transport Protein and Acyl-CoA Synthetase Genes by PPARα and PPARγ Activators

    Geneviève Martin;Kristina Schoonjans;Anne-Marie Lefebvre;Bart Staels

  • Peroxisome proliferator-activated receptors, orphans with ligands and functions

    Kristina Schoonjans;Geneviève Martin;Bart Staels;Johan Auwerx

  • Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies.

    Pierre Desreumaux;Laurent Dubuquoy;Sophie Nutten;Michel Peuchmaur

  • Regulation of Peroxisome Proliferator-Activated Receptor γ Expression by Adipocyte Differentiation and Determination Factor 1/Sterol Regulatory Element Binding Protein 1: Implications for Adipocyte Differentiation and Metabolism

    Lluis Fajas;Kristina Schoonjans;Laurent Gelman;Jae B. Kim

  • TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading.

    Thijs Pols;Mitsunori Nomura;Taoufiq Harach;Giuseppe Lo Sasso

  • LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis.

    Elisabeth Fayard;Johan Auwerx;Kristina Schoonjans

Frequent Co-Authors

Johan Auwerx
Johan Auwerx École Polytechnique Fédérale de Lausanne
Bart Staels
Bart Staels University of Lille
Roberto Pellicciari
Roberto Pellicciari University of Perugia
Thomas Brunner
Thomas Brunner University of Konstanz
Sander M. Houten
Sander M. Houten Icahn School of Medicine at Mount Sinai
Fredrik Bäckhed
Fredrik Bäckhed University of Gothenburg
Carles Cantó
Carles Cantó Nestlé (Switzerland)
Jean-Charles Fruchart
Jean-Charles Fruchart Institut Pasteur
Matthias Schmuth
Matthias Schmuth Innsbruck Medical University
Walter Wahli
Walter Wahli University of Lausanne

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