Sander M. Houten spends much of his time researching Internal medicine, Endocrinology, Biochemistry, Insulin resistance and Mitochondrion. His research links Farnesoid X receptor with Internal medicine. His studies in Farnesoid X receptor integrate themes in fields like Receptor and Small heterodimer partner.
His Endocrinology research is multidisciplinary, incorporating elements of Nuclear receptor and Cytokine. The concepts of his Insulin resistance study are interwoven with issues in FOXO1, Metabolic syndrome and NAD+ kinase. His research integrates issues of Acetyl-CoA, Carnitine and Homeostasis in his study of Mitochondrion.
Internal medicine, Endocrinology, Biochemistry, Beta oxidation and Insulin resistance are his primary areas of study. Adipose tissue, Lipotoxicity, Knockout mouse, Myopathy and Carbohydrate metabolism are among the areas of Internal medicine where he concentrates his study. His work on Fatty acid expands to the thematically related Endocrinology.
His Biochemistry and Enzyme, Peroxisome, Mitochondrion, Metabolism and Dehydrogenase investigations all form part of his Biochemistry research activities. His Beta oxidation study frequently links to other fields, such as Acyl CoA dehydrogenase. Sander M. Houten studies Glucose homeostasis which is a part of Insulin resistance.
Biochemistry, Internal medicine, Endocrinology, DHTKD1 and Mitochondrion are his primary areas of study. His work in the fields of Biochemistry, such as Enzyme, Dehydrogenase, Lysine and Metabolism, intersects with other areas such as Saccharopine. The study incorporates disciplines such as Haploinsufficiency and Glucose lowering in addition to Internal medicine.
His Endocrinology research incorporates themes from Glutamine and Long-chain acyl-CoA dehydrogenase. His studies deal with areas such as Genetics, High-throughput screening, BCKDHB, Messenger RNA and Exon as well as DHTKD1. Sander M. Houten studied Mitochondrion and Peroxisome that intersect with Carnitine, Orchiectomy, Acute kidney injury and Transcriptome.
Sander M. Houten mostly deals with Mitochondrion, Biochemistry, Peroxisome, Carnitine and Internal medicine. His work on Dehydrogenase, Dihydrolipoamide dehydrogenase, Oxidoreductase and OGDH is typically connected to Glutaric Acidemia Type 1 as part of general Biochemistry study, connecting several disciplines of science. His Peroxisome study incorporates themes from Metabolite, Beta oxidation, Metabolism and Inner mitochondrial membrane.
Sander M. Houten interconnects Gene, Long-chain acyl-CoA dehydrogenase and Carnitine biosynthesis in the investigation of issues within Carnitine. His Internal medicine research includes elements of Endocrinology and Allele. His Endocrinology research is multidisciplinary, relying on both Haploinsufficiency and Toxicity.
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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
Mitsuhiro Watanabe;Sander M. Houten;Chikage Mataki;Marcelo A. Christoffolete.
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c.
Mitsuhiro Watanabe;Sander M. Houten;Li Wang;Antonio Moschetta.
Journal of Clinical Investigation (2004)
A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation
Sander Michel Houten;Ronald J. A. Wanders.
Journal of Inherited Metabolic Disease (2010)
Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation
Jérôme N. Feige;Marie Lagouge;Carles Canto;Axelle Strehle.
Cell Metabolism (2008)
Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism
Mary Elizabeth Patti;Mary Elizabeth Patti;Sander M. Houten;Antonio C. Bianco;Raquel Bernier.
Endocrine functions of bile acids
Sander M Houten;Mitsuhiro Watanabe;Johan Auwerx.
The EMBO Journal (2006)
Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome
S. M. Houten;W. Kuis;M. Duran;T. J. De Koning.
Nature Genetics (1999)
Acylcarnitines: reflecting or inflicting insulin resistance?
Marieke G. Schooneman;Frédéric M. Vaz;Sander M. Houten;Maarten R. Soeters.
The metabolic footprint of aging in mice
Riekelt H. Houtkooper;Carmen Argmann;Sander M. Houten;Carles Cantó.
Scientific Reports (2011)
The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders
Sander M. Houten;Sara Violante;Fatima V. Ventura;Ronald J.A. Wanders.
Annual Review of Physiology (2016)
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