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Biology and Biochemistry

D-Index
74
Citations
21895
World Ranking
5545
National Ranking
2634

Overview

Sander M. Houten is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research focuses primarily on the intersection of biochemistry, genetics, and molecular biology, with notable contributions across the fields of medicine and clinical biochemistry. The main subfields of their study include molecular biology, clinical biochemistry, physiology, biochemistry, and neurology.

Their work covers several research topics, including:

  • Metabolism and Genetic Disorders
  • Biochemical and Molecular Research
  • Peroxisome Proliferator-Activated Receptors
  • Mitochondrial Function and Pathology
  • RNA modifications and cancer
  • Adipose Tissue and Metabolism
  • Biochemical Acid Research Studies

Houten has published extensively in several academic venues, among which bioRxiv (Cold Spring Harbor Laboratory) stands out with 17 publications. Other frequent venues include the Journal of Inherited Metabolic Disease, Molecular Genetics and Metabolism, ACS Chemical Biology, and Gastroenterology.

Their recent papers include:

  • Metabolic interactions between peroxisomes and mitochondria with a special focus on acylcarnitine metabolism, 2020, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  • Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2-related Disease, 2020, Gastroenterology
  • A mechanistic framework for cardiometabolic and coronary artery diseases, 2022, Nature Cardiovascular Research
  • The lysine degradation pathway: Subcellular compartmentalization and enzyme deficiencies, 2020, Molecular Genetics and Metabolism
  • PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes, 2022, Cell stem cell

Collaboration is an important aspect of Houten's work, with frequent co-authors including Tetyana Dodatko, Carmen Argmann, João Leandro, Chunli Yu, and Pablo Ranea-Robles.

Best Publications

  • Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

    Mitsuhiro Watanabe;Sander M. Houten;Chikage Mataki;Marcelo A. Christoffolete

  • Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c.

    Mitsuhiro Watanabe;Sander M. Houten;Li Wang;Antonio Moschetta

  • A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation

    Sander Michel Houten;Ronald J. A. Wanders

  • Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

    Jérôme N. Feige;Marie Lagouge;Carles Canto;Axelle Strehle

  • Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism

    Mary Elizabeth Patti;Mary Elizabeth Patti;Sander M. Houten;Antonio C. Bianco;Raquel Bernier

  • Endocrine functions of bile acids

    Sander M Houten;Mitsuhiro Watanabe;Johan Auwerx

  • The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders

    Sander M. Houten;Sara Violante;Fatima V. Ventura;Ronald J.A. Wanders

  • Acylcarnitines: reflecting or inflicting insulin resistance?

    Marieke G. Schooneman;Frédéric M. Vaz;Sander M. Houten;Maarten R. Soeters

  • Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome

    S. M. Houten;W. Kuis;M. Duran;T. J. De Koning

  • The metabolic footprint of aging in mice

    Riekelt H. Houtkooper;Carmen Argmann;Sander M. Houten;Carles Cantó

  • Systems proteomics of liver mitochondria function

    Evan G. Williams;Yibo Wu;Pooja Jha;Sébastien Dubuis

  • PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure

    Péter Bai;Péter Bai;Carles Canto;Attila Brunyánszki;Aline Huber

  • Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

    Mitsuhiro Watanabe;Yasushi Horai;Sander M. Houten;Kohkichi Morimoto

  • Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Reference Population

    Yibo Wu;Evan G. Williams;Sébastien Dubuis;Adrienne Mottis

  • Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ hypomorphic mice

    Hana Koutnikova;Terrie-Anne Cock;Mitsuhiro Watanabe;Sander M. Houten

  • The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results

    Ronald J. A. Wanders;Jos P. N. Ruiter;Lodewijk IJlst;Hans R. Waterham

  • Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome.

    Joost Frenkel;Ger T. Rijkers;Saskia H. L. Mandey;Sandra W. M. Buurman

  • Acyl-CoA Dehydrogenase 9 Is Required for the Biogenesis of Oxidative Phosphorylation Complex I

    Jessica Nouws;Leo Nijtmans;Sander M. Houten;Mariël van den Brand

  • Mitochondrial protein acetylation is driven by acetyl-CoA from fatty acid oxidation

    Olga Pougovkina;Heleen te Brinke;Rob Ofman;Arno G. van Cruchten

  • Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.

    Chikage Mataki;Benjamin C. Magnier;Sander M. Houten;Jean-Sébastien Annicotte

Frequent Co-Authors

Ronald J.A. Wanders
Ronald J.A. Wanders University of Amsterdam
Johan Auwerx
Johan Auwerx École Polytechnique Fédérale de Lausanne
Hans R. Waterham
Hans R. Waterham University of Amsterdam
Marinus Duran
Marinus Duran University of Amsterdam
Jos P.N. Ruiter
Jos P.N. Ruiter University of Amsterdam
Kristina Schoonjans
Kristina Schoonjans École Polytechnique Fédérale de Lausanne
Eric E. Schadt
Eric E. Schadt Icahn School of Medicine at Mount Sinai
Jun Zhu
Jun Zhu Icahn School of Medicine at Mount Sinai
Lodewijk IJlst
Lodewijk IJlst University of Amsterdam
Frédéric M. Vaz
Frédéric M. Vaz University of Amsterdam

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