His primary areas of study are Immunology, Cell biology, Chemokine, Inflammation and Chemokine receptor. His work in the fields of Immunology, such as Acquired immune system, intersects with other areas such as Decoy receptors. He has researched Cell biology in several fields, including Cellular differentiation, Gene expression profiling, Transcriptome, CCL7 and Interleukin 10.
His Cellular differentiation study integrates concerns from other disciplines, such as Tumor-associated macrophage, Mononuclear phagocyte system and Macrophage polarization. His Chemokine study deals with the bigger picture of Receptor. His Inflammation study combines topics in areas such as Colitis, Angiogenesis, Macrophage and Inflammatory bowel disease.
The scientist’s investigation covers issues in Cell biology, Immunology, Chemokine, Chemokine receptor and Inflammation. His Cell biology study deals with Macrophage intersecting with Interleukin 4. His work on CCL7, Innate immune system and Proinflammatory cytokine as part of general Immunology study is frequently linked to Scavenger receptor, therefore connecting diverse disciplines of science.
In his study, CCR2 is strongly linked to Cancer research, which falls under the umbrella field of Chemokine. His research integrates issues of Transcription factor, Immune system, Fibrosis, Pathology and Metastasis in his study of Inflammation. His research investigates the connection with Receptor and areas like Pharmacology which intersect with concerns in Allosteric regulation.
His primary areas of investigation include Chemokine receptor, Cell biology, Chemokine, Inflammation and Cancer research. Receptor and Immunology are inextricably linked to his Chemokine receptor research. The Immunology study combines topics in areas such as Bronchoalveolar lavage and Lung injury.
His Cell biology research is multidisciplinary, incorporating perspectives in CC chemokine receptors, Macrophage and CXC chemokine receptors. His biological study focuses on CCR2. Massimo Locati has researched Inflammation in several fields, including Therapeutic targeting, Downregulation and upregulation, Transcription factor, Immune system and Fibrosis.
Massimo Locati mainly focuses on Cell biology, Chemokine, Inflammation, Chemokine receptor and Cancer research. The Cell biology study combines topics in areas such as Tumor progression and Macrophage. His research in Chemokine intersects with topics in Cell migration, Angiogenesis, Disease and Tumor growth.
His Inflammation study is associated with Immunology. His Chemokine receptor research is multidisciplinary, incorporating perspectives in Lesion, Anesthesia and Mortality rate. The study incorporates disciplines such as Cancer, Cancer immunotherapy, Immunotherapy and Tumor stroma in addition to Cancer research.
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The chemokine system in diverse forms of macrophage activation and polarization.
Alberto Mantovani;Alberto Mantovani;Antonio Sica;Silvano Sozzani;Silvano Sozzani;Paola Allavena.
Trends in Immunology (2004)
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
Alberto Mantovani;Alberto Mantovani;Silvano Sozzani;Silvano Sozzani;Massimo Locati;Paola Allavena.
Trends in Immunology (2002)
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
Peter J Murray;Judith E Allen;Subhra K Biswas;Edward A Fisher.
Macrophage activation and polarization.
Fernando Oneissi Martinez;Antonio Sica;Alberto Mantovani;Massimo Locati.
Frontiers in Bioscience (2008)
Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression
Fernando O. Martinez;Siamon Gordon;Massimo Locati;Alberto Mantovani.
Journal of Immunology (2006)
Macrophage plasticity and polarization in tissue repair and remodelling.
Alberto Mantovani;Subhra K Biswas;Maria Rosaria Galdiero;Antonio Sica.
The Journal of Pathology (2013)
Macrophage Polarization Comes of Age
Alberto Mantovani;Antonio Sica;Massimo Locati.
International Union of Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors
Francoise Bachelerie;Adit Ben-Baruch;Amanda M. Burkhardt;Christophe Combadiere.
Pharmacological Reviews (2014)
Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals.
Flavia Bazzoni;Marzia Rossato;Marco Fabbri;Daniele Gaudiosi.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Tuning inflammation and immunity by chemokine sequestration: decoys and more
Alberto Mantovani;Raffaella Bonecchi;Massimo Locati.
Nature Reviews Immunology (2006)
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