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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
11312
World Ranking
13248
National Ranking
922

Overview

Shuki Mizutani is affiliated with Tokyo Medical and Dental University in Japan and has contributed extensively to the field of medicine through research focusing on physiology, periodontics, speech and hearing, neurology, and molecular biology. Their work frequently addresses topics related to dysphagia assessment and management, nutrition and health in aging, dental health and care utilization, frailty in older adults, S100 proteins and annexins, oral microbiology and periodontitis research, and Alzheimer's disease research and treatments.

Recent publications by Mizutani cover a range of studies related primarily to aging, oral health, and neurological conditions. Selected notable papers include:

  • GSK3β is involved in promoting Alzheimer's disease pathologies following chronic systemic exposure to Porphyromonas gingivalis lipopolysaccharide in amyloid precursor proteinNL-F/NL-F knock-in mice (2021, Brain Behavior and Immunity)
  • A Cross-Sectional Study of Age-Related Changes in Oral Function in Healthy Japanese Individuals (2020, International Journal of Environmental Research and Public Health)
  • Association between oral function and physical pre-frailty in community-dwelling older people: a cross-sectional study (2022, BMC Geriatrics)
  • Low Tongue Strength and the Number of Teeth Present Are Associated with Cognitive Decline in Older Japanese Dental Outpatients: A Cross-Sectional Study (2020, International Journal of Environmental Research and Public Health)
  • Relationship between cerebral atrophy and number of present teeth in elderly individuals with cognitive decline (2020, Experimental Gerontology)

Mizutani often collaborates with several researchers, including Haruhiko Kashiwazaki, Saori Oku, Kiyomi Iyota, Asuka Tani, and Zhou Wu. These collaborative efforts have contributed to the breadth and interdisciplinary nature of their research outputs.

Their research is published in a variety of academic journals, with a strong presence in the International Journal of Environmental Research and Public Health. Other frequent publication venues include Nutrients, Brain Behavior and Immunity, BMC Geriatrics, and the Journal of Oral Rehabilitation.

Mizutani's work has consistently engaged with aging populations and oral health, examining both physiological and neurological dimensions of these topics. The intersection of oral health and cognitive decline is a recurring theme, as reflected in studies focusing on tongue strength, number of teeth, cerebral atrophy, and physical frailty in older adults.

Best Publications

  • Human Tyrosine Kinase 2 Deficiency Reveals Its Requisite Roles in Multiple Cytokine Signals Involved in Innate and Acquired Immunity

    Yoshiyuki Minegishi;Masako Saito;Tomohiro Morio;Ken Watanabe

  • Clinical course of patients with WASP gene mutations

    Kohsuke Imai;Tomohiro Morio;Yi Zhu;Yinzhu Jin

  • Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion.

    F E Alexander;S L Patheal;A Biondi;S Brandalise

  • Chk2 Activation Dependence on Nbs1 after DNA Damage

    Giacomo Buscemi;Camilla Savio;Laura Zannini;Francesca Miccichè

  • Identification of a gene expression signature associated with pediatric AML prognosis

    Tomohito Yagi;Akira Morimoto;Mariko Eguchi;Shigeyoshi Hibi

  • A novel translocation, t(2;5)(p23;q35), in childhood phagocytic large T-cell lymphoma mimicking malignant histiocytosis.

    Y Kaneko;G Frizzera;S Edamura;N Maseki

  • Developmentally regulated rearrangement and expression of genes encoding the T cell receptor-T3 complex.

    A.J. Furley;S. Mizutani;K. Weilbaecher;H.S. Dhaliwal

  • Cytoplasmic p21Cip1/WAF1 regulates neurite remodeling by inhibiting Rho-kinase activity

    Hiroyuki Tanaka;Toshihide Yamashita;Minoru Asada;Shuki Mizutani

  • Mutations of the N-ras gene in juvenile chronic myelogenous leukemia.

    Jun Miyauchi;Minoru Asada;Michiko Sasaki;Yukiko Tsunematsu

  • Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients.

    Naomi Takahashi;Kenji Matsumoto;Hirohisa Saito;Toshihiro Nanki

  • Intrarenal and Cellular Localization of CLC-K2 Protein in the Mouse Kidney

    Katsuki Kobayashi;Shinichi Uchida;Shuki Mizutani;Sei Sasaki

  • Phosphorylation of histone H2AX at M phase in human cells without DNA damage response

    Yosuke Ichijima;Ryo Sakasai;Naoyuki Okita;Naoyuki Okita;Kinji Asahina

  • Outcome of risk-based therapy for infant acute lymphoblastic leukemia with or without an MLL gene rearrangement, with emphasis on late effects: a final report of two consecutive studies, MLL96 and MLL98, of the Japan Infant Leukemia Study Group

    D Tomizawa;K Koh;T Sato;N Kinukawa

  • Molecular and Virological Evidence of Viral Activation From Chromosomally Integrated Human Herpesvirus 6A in a Patient With X-Linked Severe Combined Immunodeficiency

    Akifumi Endo;Ken Watanabe;Tamae Ohye;Kyoko Suzuki

  • Autoimmune lymphoproliferative syndrome-like disease with somatic KRAS mutation

    Masatoshi Takagi;Kunihiro Shinoda;Jinhua Piao;Noriko Mitsuiki

  • The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils

    Fumiko Honda;Hirotsugu Kano;Hirokazu Kanegane;Shigeaki Nonoyama

  • Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria.

    Yaeko Motoyoshi;Taiji Matsusaka;Taiji Matsusaka;Akihiko Saito;Ira Pastan

  • Infant acute lymphoblastic leukemia with MLL gene rearrangements: outcome following intensive chemotherapy and hematopoietic stem cell transplantation

    Yoshiyuki Kosaka;Katsuyoshi Koh;Naoko Kinukawa;Yoshihiro Wakazono

  • Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2

    Kohsuke Imai;Yi Zhu;Patrick Revy;Tomohiro Morio

  • Mechanisms of neurodegeneration in mucopolysaccharidoses II and IIIB: analysis of human brain tissue

    Kimiko Hamano;Masaharu Hayashi;Kei Shioda;Ryo Fukatsu

Frequent Co-Authors

Tomohiro Morio
Tomohiro Morio Institute of Science Tokyo
Kohsuke Imai
Kohsuke Imai Tokyo Medical and Dental University
Yasuhide Hayashi
Yasuhide Hayashi Gunma Children's Medical Center
Souichi Adachi
Souichi Adachi Shiga Prefectural General Hospital
Shigeaki Nonoyama
Shigeaki Nonoyama National Defense Medical College
Domenico Delia
Domenico Delia University of Milan
Mel Greaves
Mel Greaves Institute of Cancer Research
Johji Inazawa
Johji Inazawa Tokyo Medical and Dental University
Issei Imoto
Issei Imoto University of Tokushima
Seishi Ogawa
Seishi Ogawa Kyoto University

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