World's Best Scientists 2026 revealed!
Award Badge
Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Genetics

D-Index
102
Citations
37539
World Ranking
705
National Ranking
22

Molecular Biology

D-Index
102
Citations
37539
World Ranking
498
National Ranking
35

Medicine

D-Index
102
Citations
37910
World Ranking
7668
National Ranking
187

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Johji Inazawa is affiliated with Tokyo Medical and Dental University in Japan. Their research spans multiple disciplines within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, cancer research, genetics, pulmonary and respiratory medicine, and surgery.

The main topics covered in their work include cancer genomics and diagnostics, epigenetics and DNA methylation, protein degradation and inhibitors, genomics and chromatin dynamics, neuroscience and neuropharmacology research, cholangiocarcinoma and gallbladder cancer studies, and cancer-related gene regulation.

Inazawa has contributed research articles to several publication venues, frequently publishing in the Journal of Human Genetics, eLife, Molecular Therapy - Oncolytics, Cancer Science, and Nature Genetics.

Recent publications by Inazawa consist of:

  • Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases, 2020, Nature Genetics
  • Cancer-associated miRNAs and their therapeutic potential, 2021, Journal of Human Genetics
  • Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation, 2021, Science Advances
  • miR-1293, a Candidate for miRNA-Based Cancer Therapeutics, Simultaneously Targets BRD4 and the DNA Repair Pathway, 2020, Molecular Therapy
  • Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment, 2020, Molecular Therapy - Oncolytics

Frequent coauthors collaborating with Inazawa include:

  • Tomoki Muramatsu
  • Jun Inoue
  • Kousuke Tanimoto
  • Yukihide Momozawa
  • Toshihiro Tanaka

Johji Inazawa's research reflects a multidisciplinary approach integrating molecular biology techniques with clinical and therapeutic aspects of cancer and genetic diseases. Their body of work encompasses experimental studies in miRNA-based cancer therapeutics, genome-wide association studies contributing to the understanding of disease susceptibility, and investigations into protein degradation pathways relevant to embryonic development and disease processes.

Best Publications

  • Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.

    Nobuya Inagaki;Tohru Gonoi;John P. Clement;Noriyuki Namba

  • Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer

    Qing Lin Li;Kosei Ito;Chohei Sakakura;Hiroshi Fukamachi

  • Structure and Chromosomal Localization of the Human Stromal Cell-Derived Factor 1 (SDF1) Gene

    Michio Shirozu;Toru Nakano;Johji Inazawa;Kei Tashiro

  • Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer.

    Ken Ichi Kozaki;Issei Imoto;Seiki Mogi;Ken Omura

  • miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma

    Mayuko Furuta;Ken Ich Kozaki;Shinji Tanaka;Shigeki Arii

  • Human Fas ligand: gene structure, chromosomal location and species specificity

    Tomohiro Takahashi;Masato Tanaka;Johji Inazawa;Tatsuo Abe

  • Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

    Kazuyoshi Ishigaki;Kazuyoshi Ishigaki;Masato Akiyama;Masahiro Kanai;Masahiro Kanai;Atsushi Takahashi

  • Damaged epithelia regenerated by bone marrow–derived cells in the human gastrointestinal tract

    Ryuichi Okamoto;Tomoharu Yajima;Motomi Yamazaki;Takanori Kanai

  • HSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activator.

    A Nakai;M Tanabe;Y Kawazoe;J Inazawa

  • Mutations in EFHC1 cause juvenile myoclonic epilepsy

    Toshimitsu Suzuki;Toshimitsu Suzuki;Antonio V Delgado-Escueta;Kripamoy Aguan;Maria E Alonso

  • Genetic Variants in C5 and Poor Response to Eculizumab

    Jun-ichi Nishimura;Masaki Yamamoto;Shin Hayashi;Kazuma Ohyashiki

  • Mammalian occludin in epithelial cells: its expression and subcellular distribution.

    M Saitou;Y Ando-Akatsuka;M Itoh;M Furuse

  • Structural organization and chromosomal assignment of the human obese gene.

    Naohi Isse;Yoshihiro Ogawa;Naohisa Tamura;Hiroaki Masuzaki

  • Clinical heterogeneity of α‐synuclein gene duplication in Parkinson's disease

    Kenya Nishioka;Shin Hayashi;Matthew J. Farrer;Andrew B. Singleton

  • Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population

    Ryo Takata;Shusuke Akamatsu;Michiaki Kubo;Atsushi Takahashi

  • Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.

    Jun Ishikawa;Tsuneyasu Kaisho;Hitoshi Tomizawa;Byung Ok Lee

  • PH Domain-Only Protein PHLDA3 Is a p53-Regulated Repressor of Akt

    Tatsuya Kawase;Tatsuya Kawase;Rieko Ohki;Tatsuhiro Shibata;Shuichi Tsutsumi

  • Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation.

    C Sakakura;A Hagiwara;R Yasuoka;Y Fujita

  • Reprimo, a new candidate mediator of the p53-mediated cell cycle arrest at the G2 phase.

    Rieko Ohki;Jiro Nemoto;Hideki Murasawa;Eri Oda

  • Structural organization of the human oxytocin receptor gene.

    T Inoue;T Kimura;C Azuma;J Inazawa

Frequent Co-Authors

Issei Imoto
Issei Imoto University of Tokushima
Tatsuo Abe
Tatsuo Abe Kyoto Prefectural University of Medicine
Yusuke Nakamura
Yusuke Nakamura National Institutes of Biomedical Innovation, Health and Nutrition
Hitoshi Tsuda
Hitoshi Tsuda National Defense Medical College
Setsuo Hirohashi
Setsuo Hirohashi National Cancer Research Institute, UK
Masafumi Taniwaki
Masafumi Taniwaki Kyoto Prefectural University of Medicine
Tatsuhiro Shibata
Tatsuhiro Shibata University of Tokyo
Yutaka Shimada
Yutaka Shimada Kyoto University
Fumie Hosoda
Fumie Hosoda National Cancer Centre
Yae Kanai
Yae Kanai Keio University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology opens the door to many related online degrees and flexible career paths. With advancements in distance learning, students can now pursue accredited programs from the comfort of their homes. Choosing to study at one of the non profit universities ensures you receive a recognized education, often at a lower cost and with a commitment to student success.

For those with a military background or active service members, military friendly online colleges offer specialized support services and flexible schedules designed to accommodate your unique needs.

If you are interested in merging biology with human services, you may consider online graduate programs in adjacent disciplines. For example, an social work online master's programs can help you apply scientific thinking to community wellness. Similarly, those leaning toward health and behavior sciences can pursue an online masters in psychology, some of which offer accelerated pathways for quick entry into the workforce.

With these options, you can tailor your educational journey in science, social impact, or mental health, all with the flexibility and support of reputable online programs.

Best Scientists Citing Johji Inazawa

Trending Scientists