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Tatsuhiro Shibata

Tatsuhiro Shibata

D-Index & Metrics

Medicine

D-Index
101
Citations
60639
World Ranking
7801
National Ranking
192

Overview

Tatsuhiro Shibata is affiliated with the University of Tokyo in Japan. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Cancer Research, and Oncology. Additional subfields of study include Pulmonary and Respiratory Medicine as well as Pathology and Forensic Medicine.

The main topics of Shibata's work encompass Cancer Genomics and Diagnostics, Genetic factors in colorectal cancer, Cancer Immunotherapy and Biomarkers, Epigenetics and DNA Methylation, Glioma Diagnosis and Treatment, Cholangiocarcinoma and Gallbladder Cancer Studies, and Colorectal Cancer Treatments and Studies.

Shibata has published extensively, with frequent publications appearing in venues such as Nature Communications, Cancer Research, Brain Tumor Pathology, Neuro-Oncology, and bioRxiv (Cold Spring Harbor Laboratory).

Selected recent papers include:

  • "Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence" (2021, Nature Genetics)
  • "Sex differences in oncogenic mutational processes" (2020, Nature Communications)
  • "Spatial and single-cell transcriptomics decipher the cellular environment containing HLA-G+ cancer cells and SPP1+ macrophages in colorectal cancer" (2023, Cell Reports)
  • "Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway" (2021, Nature Communications)
  • "Whole-genome landscape of adult T-cell leukemia/lymphoma" (2021, Blood)

Frequent co-authors in Shibata's research include Yasuhito Arai, Natsuko Hama, Hiromi Nakamura, Mamoru Kato, and Yasushi Totoki.

Best Publications

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

    Adrian Ally;Miruna Balasundaram;Rebecca Carlsen;Eric Chuah

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer

    Shinichi Yachida;Sayaka Mizutani;Hirotsugu Shiroma;Satoshi Shiba

  • Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

    Yoichiro Mitsuishi;Keiko Taguchi;Yukie Kawatani;Tatsuhiro Shibata

  • Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

    Jakob Wirbel;Paul Theodor Pyl;Paul Theodor Pyl;Ece Kartal;Konrad Zych

  • Genomic spectra of biliary tract cancer

    Hiromi Nakamura;Yasuhito Arai;Yasushi Totoki;Tomoki Shirota

  • Mutational signatures associated with tobacco smoking in human cancer

    Ludmil B Alexandrov;Ludmil B Alexandrov;Young Seok Ju;Kerstin Haase;Peter Van Loo;Peter Van Loo

  • Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

    Tatsuhiro Shibata;Tsutomu Ohta;Kit I. Tong;Akiko Kokubu

  • Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

    Andrew Maltez Thomas;Andrew Maltez Thomas;Paolo Manghi;Francesco Asnicar;Edoardo Pasolli

  • KIF5B-RET fusions in lung adenocarcinoma.

    Takashi Kohno;Hitoshi Ichikawa;Yasushi Totoki;Kazuki Yasuda

  • Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

    Akihiro Fujimoto;Yasushi Totoki;Tetsuo Abe;Keith A. Boroevich

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Integrated molecular analysis of adult T cell leukemia/lymphoma

    Keisuke Kataoka;Yasunobu Nagata;Akira Kitanaka;Yuichi Shiraishi

  • Epidermal Growth Factor Receptor Gene Mutations and Increased Copy Numbers Predict Gefitinib Sensitivity in Patients With Recurrent Non–Small-Cell Lung Cancer

    Toshimi Takano;Yuichiro Ohe;Hiromi Sakamoto;Koji Tsuta

  • Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas.

    Hirokazu Okayama;Takashi Kohno;Yuko Ishii;Yoko Shimada

  • Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma

    Apinya Jusakul;Apinya Jusakul;Ioana Cutcutache;Chern Han Yong;Jing Quan Lim

  • Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

    Yasushi Totoki;Kenji Tatsuno;Kyle R. Covington;Hiroki Ueda

  • Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

    Tsutomu Ohta;Kumiko Iijima;Mamiko Miyamoto;Izumi Nakahara

Frequent Co-Authors

Yasushi Totoki
Yasushi Totoki National Cancer Centre
Setsuo Hirohashi
Setsuo Hirohashi National Cancer Research Institute, UK
Fumie Hosoda
Fumie Hosoda National Cancer Centre
Yasuhito Arai
Yasuhito Arai National Cancer Centre
Yae Kanai
Yae Kanai Keio University
Satoru Miyano
Satoru Miyano Tokyo Medical and Dental University
Hitoshi Tsuda
Hitoshi Tsuda National Defense Medical College
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Koji Tsuta
Koji Tsuta Kansai Medical University
Johji Inazawa
Johji Inazawa Tokyo Medical and Dental University

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