World's Best Scientists 2026 revealed!
Yasushi Totoki

Yasushi Totoki

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
18056
World Ranking
17823
National Ranking
1287

Overview

Yasushi Totoki is affiliated with the National Cancer Centre in Japan and has contributed extensively to research in medicine, biochemistry, genetics, and molecular biology. Their scholarly work focuses on fields such as molecular biology, cancer research, surgery, oncology, and pathology and forensic medicine.

The primary topics addressed in their research include:

  • Cancer Genomics and Diagnostics
  • Genetic factors in colorectal cancer
  • Epigenetics and DNA Methylation
  • Glioma Diagnosis and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Gastric Cancer Management and Outcomes
  • RNA modifications and cancer

Yasushi Totoki has published articles in several notable scientific venues, including:

  • Neuro-Oncology
  • Nature Communications
  • Cancer Science
  • Annals of Surgery
  • Science Advances

Prominent recent papers authored or coauthored by Yasushi Totoki are:

  • "Multiancestry genomic and transcriptomic analysis of gastric cancer," 2023, Nature Genetics
  • "Defined lifestyle and germline factors predispose Asian populations to gastric cancer," 2020, Science Advances
  • "Ependymoma with C11orf95-MAML2 fusion: presenting with granular cell and ganglion cell features," 2020, Brain Tumor Pathology
  • "Transcriptome and methylome analysis of CNS germ cell tumor finds its cell-of-origin in embryogenesis and reveals shared similarities with testicular counterparts," 2022, Neuro-Oncology
  • "Whole-exome Sequencing Reveals New Potential Susceptibility Genes for Japanese Familial Pancreatic Cancer," 2020, Annals of Surgery

Their frequent collaborators include:

  • Tatsuhiro Shibata
  • Hiromi Nakamura
  • Shinichi Yachida
  • Natsuko Hama
  • Yasuhito Arai

The body of work by Yasushi Totoki spans multiple disciplines relevant to cancer biology and genetics, contributing frequent studies on the molecular underpinnings and diagnostic aspects of cancer. Their work integrates genomic, transcriptomic, and epigenetic data to advance understanding in areas such as gastric cancer, pancreatic cancer, and central nervous system tumors.

Best Publications

  • Initial sequencing and analysis of the human genome.

    Eric S. Lander;Lauren M. Linton;Bruce Birren;Chad Nusbaum

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

    Adrian Ally;Miruna Balasundaram;Rebecca Carlsen;Eric Chuah

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • The DNA sequence of human chromosome 21

    M. Hattori;A. Fujiyama;T. D. Taylor;H. Watanabe

  • Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

    Toshiaki Watanabe;Toshiaki Watanabe;Yasushi Totoki;Atsushi Toyoda;Masahiro Kaneda;Masahiro Kaneda

  • Genomic spectra of biliary tract cancer

    Hiromi Nakamura;Yasuhito Arai;Yasushi Totoki;Tomoki Shirota

  • Mutational signatures associated with tobacco smoking in human cancer

    Ludmil B Alexandrov;Ludmil B Alexandrov;Young Seok Ju;Kerstin Haase;Peter Van Loo;Peter Van Loo

  • DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

    Satomi Kuramochi-Miyagawa;Toshiaki Watanabe;Kengo Gotoh;Yasushi Totoki

  • KIF5B-RET fusions in lung adenocarcinoma.

    Takashi Kohno;Hitoshi Ichikawa;Yasushi Totoki;Kazuki Yasuda

  • Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

    Akihiro Fujimoto;Yasushi Totoki;Tetsuo Abe;Keith A. Boroevich

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Integrated molecular analysis of adult T cell leukemia/lymphoma

    Keisuke Kataoka;Yasunobu Nagata;Akira Kitanaka;Yuichi Shiraishi

  • Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma

    Apinya Jusakul;Apinya Jusakul;Ioana Cutcutache;Chern Han Yong;Jing Quan Lim

  • Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

    Yasushi Totoki;Kenji Tatsuno;Kyle R. Covington;Hiroki Ueda

  • Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

    Akihiro Fujimoto;Mayuko Furuta;Yasushi Totoki;Tatsuhiko Tsunoda

  • Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

    Keisuke Kataoka;Yuichi Shiraishi;Yohei Takeda;Seiji Sakata

  • Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma

    Yasuhito Arai;Yasushi Totoki;Fumie Hosoda;Tomoki Shirota

  • Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus.

    Toshiaki Watanabe;Toshiaki Watanabe;Shin Ichi Tomizawa;Shin Ichi Tomizawa;Kohzoh Mitsuya;Yasushi Totoki

Frequent Co-Authors

Tatsuhiro Shibata
Tatsuhiro Shibata University of Tokyo
Atsushi Toyoda
Atsushi Toyoda National Institute of Genetics
Fumie Hosoda
Fumie Hosoda National Cancer Centre
Yasuhito Arai
Yasuhito Arai National Cancer Centre
Satoru Miyano
Satoru Miyano Tokyo Medical and Dental University
Yoshiyuki Sakaki
Yoshiyuki Sakaki Toyohashi University of Technology
Hiroyuki Sasaki
Hiroyuki Sasaki Kyushu University
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Takuji Okusaka
Takuji Okusaka National Cancer Centre
Seishi Ogawa
Seishi Ogawa Kyoto University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in Biology and Biochemistry, a range of online degrees offer flexible pathways into dynamic healthcare and research careers. Many learners begin with foundational studies and look to specialize further with industry-focused credentials.

For those passionate about nutrition science, an online master's degree in nutrition can open doors to advanced roles in community health, clinical research, or public policy. If your career interests lie in diagnostic imaging, ultrasound tech school online programs provide hands-on learning and certification options.

Students seeking a fast track into healthcare technology may consider online associate radiology tech programs. These offer practical training and prepare graduates for licensure exams. For those aiming to become registered dietitians, the best dietetics programs deliver evidence-based curricula that meet rigorous certification requirements.

Whether you choose to focus on biochemistry research or allied health professions, exploring related online degrees can boost your expertise and career options in the evolving life sciences sector.

Best Scientists Citing Yasushi Totoki

Trending Scientists

Recently Published Articles