What is he best known for?
The fields of study he is best known for:
Issei Imoto spends much of his time researching Cancer research, Carcinogenesis, Molecular biology, Cancer and Comparative genomic hybridization.
His Cancer research research is multidisciplinary, relying on both Cell culture, Epidermoid carcinoma, Cell growth, DNA methylation and Gene silencing.
His work deals with themes such as Methylation and microRNA, which intersect with DNA methylation.
His study in Molecular biology is interdisciplinary in nature, drawing from both Gene expression, Gene and HNF1B.
His work focuses on many connections between Cancer and other disciplines, such as Pathology, that overlap with his field of interest in Internal medicine, Gene knockdown, Digital polymerase chain reaction and Reference gene.
His Comparative genomic hybridization research is included under the broader classification of Genetics.
His most cited work include:
- Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. (521 citations)
- miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma (488 citations)
- Clinical heterogeneity of α‐synuclein gene duplication in Parkinson's disease (256 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Genetics, Cancer research, Molecular biology, Gene and Cancer.
While the research belongs to areas of Cancer research, Issei Imoto spends his time largely on the problem of Carcinogenesis, intersecting his research to questions surrounding DNA methylation.
His study on DNA methylation also encompasses disciplines like
- Gene silencing that intertwine with fields like Methylation,
- Epigenetics which connect with CpG site.
Issei Imoto has researched Molecular biology in several fields, including Fluorescence in situ hybridization, Gene expression and Chromosomal translocation.
Many of his studies on Cancer apply to Pathology as well.
His Comparative genomic hybridization study combines topics in areas such as Gene dosage and Candidate gene.
He most often published in these fields:
- Genetics (34.18%)
- Cancer research (29.43%)
- Molecular biology (24.37%)
What were the highlights of his more recent work (between 2016-2021)?
- Genetics (34.18%)
- Gene (23.73%)
- Genome-wide association study (6.01%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Genetics, Gene, Genome-wide association study, Cancer research and Internal medicine.
Issei Imoto combines subjects such as Schizophrenia, Computational biology, Genetic testing and Precision oncology with his study of Gene.
His Cancer research research integrates issues from Cell culture, Carcinogenesis, Cancer, Fallopian tube and Gene silencing.
His Cancer study incorporates themes from Epstein–Barr virus, Intensive care medicine and Pathology.
His work carried out in the field of Gene silencing brings together such families of science as Epigenetics, Cell growth and Candidate gene.
The concepts of his Internal medicine study are interwoven with issues in Endocrinology and Oncology.
Between 2016 and 2021, his most popular works were:
- Monitoring the HER2 copy number status in circulating tumor DNA by droplet digital PCR in patients with gastric cancer (71 citations)
- Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases (30 citations)
- Protease-Activated Receptor-2 Plays a Critical Role in Vascular Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice. (28 citations)
In his most recent research, the most cited papers focused on:
Issei Imoto mainly investigates Genetics, Gene, Genome-wide association study, Internal medicine and DNA methylation.
His Genetics study frequently links to other fields, such as Developmental disorder.
His Gene research is multidisciplinary, incorporating elements of Genetic counseling, Schizophrenia, Ovarian cancer and Family history.
His research integrates issues of Reference gene and Digital polymerase chain reaction in his study of Internal medicine.
He is studying CpG site, which is a component of DNA methylation.
The Methylation study combines topics in areas such as Gene silencing and Epigenetics.
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