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Genetics

D-Index
72
Citations
31060
World Ranking
2090
National Ranking
951

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2003 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Isidore Rigoutsos is affiliated with Thomas Jefferson University in the United States and has a research focus primarily situated in the field of Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Molecular Biology, Cancer Research, Hepatology, Immunology, and Emergency Medicine.

The researcher's main areas of study include cancer-related molecular mechanisms, RNA modifications and cancer, microRNA in disease regulation, RNA and protein synthesis mechanisms, RNA research and splicing, circular RNAs in diseases, and gene expression and cancer classification.

Recent publications highlight Rigoutsos's involvement in advancing knowledge about RNA biology and molecular processes related to cancer and cell regulation. Notable papers are:

  • On the expanding roles of tRNA fragments in modulating cell behavior, 2020, published in Nucleic Acids Research
  • Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer, 2020, published in Gut
  • Ribosomal RNA fragmentation into short RNAs (rRFs) is modulated in a sex- and population of origin-specific manner, 2020, published in BMC Biology
  • Unraveling the role of microRNA/isomiR network in multiple primary melanoma pathogenesis, 2021, published in Cell Death and Disease
  • IsoMiRmap: fast, deterministic and exhaustive mining of isomiRs from short RNA-seq datasets, 2021, published in Bioinformatics

Frequent co-authors collaborating with Rigoutsos include Phillipe Loher, Tess Cherlin, Venetia Pliatsika, Stepan Nersisyan, and Eric Londin. This network implies a strong cooperative environment focused on RNA research and cancer studies.

The main venues chosen for publication by Rigoutsos reflect a preference for journals and repositories specializing in molecular and biomedical sciences, such as bioRxiv (Cold Spring Harbor Laboratory), Cancer Epidemiology Biomarkers & Prevention, Nucleic Acids Research, BMC Biology, and UNC Libraries.

Isidore Rigoutsos has been recognized within the scientific community, having received the Fellow of the American Association for the Advancement of Science (AAAS) in 2020 and a fellowship from the Indian National Academy of Engineering (INAE) in 2003.

Best Publications

  • A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes

    Kevin C. Miranda;Tien Huynh;Yvonne Tay;Yen-Sin Ang

  • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

    Benjamin J. Raphael;Ralph H. Hruban;Andrew J. Aguirre;Richard A. Moffitt

  • The draft genome of Ciona intestinalis : insights into chordate and vertebrate origins

    Paramvir Dehal;Yutaka Satou;Robert K. Campbell;Jarrod Chapman

  • MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

    Yvonne Tay;Jinqiu Zhang;Andrew M. Thomson;Bing Lim;Bing Lim

  • Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite.

    Falk Warnecke;Peter Luginbühl;Natalia Ivanova;Majid Ghassemian

  • Dynamic changes in the human methylome during differentiation

    Louise Laurent;Eleanor Wong;Guoliang Li;Tien Huynh

  • Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

    Yvonne Tay;Lev Kats;Leonardo Salmena;Dror Weiss

  • The Expression of MicroRNA miR-107 Decreases Early in Alzheimer's Disease and May Accelerate Disease Progression through Regulation of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1

    Wang-Xia Wang;Bernard W. Rajeev;Arnold J. Stromberg;Na Ren

  • The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

    Elena Mogilyansky;Isidore Rigoutsos

  • Metagenomic analysis of two enhanced biological phosphorus removal (EBPR) sludge communities

    Héctor García Martín;Natalia Ivanova;Victor Kunin;Falk Warnecke

  • Combinatorial pattern discovery in biological sequences: The TEIRESIAS algorithm.

    Isidore Rigoutsos;Aris Floratos

  • The complex transcriptional landscape of the anucleate human platelet

    Paul F. Bray;Steven E. McKenzie;Leonard C. Edelstein;Srikanth Nagalla

  • Accurate phylogenetic classification of variable-length DNA fragments

    Alice Carolyn McHardy;Héctor García Martín;Aristotelis Tsirigos;Philip Hugenholtz

  • The amphioxus genome illuminates vertebrate origins and cephalochordate biology

    Linda Z. Holland;Ricard Albalat;Kaoru Azumi;Èlia Benito-Gutiérrez

  • Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs

    Eric Londina;Phillipe Lohera;Aristeidis G. Telonis;Kevin Quann

  • An algorithm for point clustering and grid generation

    M. Berger;I. Rigoutsos

  • Use of simulated data sets to evaluate the fidelity of metagenomic processing methods

    Konstantinos Mavromatis;Natalia Ivanova;Kerrie Barry;Harris Shapiro

  • FLASH: A Fast Look-Up Algorithm for String Homology

    Andrea Califano;Isidore Rigoutsos

  • High-resolution metagenomics targets specific functional types in complex microbial communities.

    Marina G Kalyuzhnaya;Alla Lapidus;Natalia Ivanova;Alex C Copeland

  • Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers

    Shozo Honda;Phillipe Loher;Megumi Shigematsu;Juan P. Palazzo

Frequent Co-Authors

Alice C. McHardy
Alice C. McHardy Helmholtz Centre for Infection Research
Aristotelis Tsirigos
Aristotelis Tsirigos New York University
Jonathan R. Brody
Jonathan R. Brody Thomas Jefferson University
Charles J. Yeo
Charles J. Yeo Thomas Jefferson University
Paolo Fortina
Paolo Fortina Thomas Jefferson University
Andrea Califano
Andrea Califano Columbia University
Asaf Salamov
Asaf Salamov Lawrence Berkeley National Laboratory
Daniel S. Rokhsar
Daniel S. Rokhsar University of California, Berkeley
Kerrie Barry
Kerrie Barry United States Department of Energy

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