His primary areas of investigation include Metastasis, Cell biology, Cancer research, Cancer cell and Mitophagy. His Metastasis study integrates concerns from other disciplines, such as KEAP1, Lung cancer and Ubiquitin ligase. His Cancer research research integrates issues from Haematopoiesis, Ubiquitin, NFE2L2, Transcription factor and Epigenetics.
His work in Epigenetics addresses issues such as Histone, which are connected to fields such as Gene silencing. His Cancer cell research includes themes of Tumor microenvironment and Cancer stem cell. His Mitophagy research is multidisciplinary, relying on both Reverse Warburg effect, Warburg effect and Stromal cell.
Aristotelis Tsirigos mainly investigates Cancer research, Cell biology, Chromatin, Gene and Epigenetics. The Cancer research study combines topics in areas such as Cancer, Tumor microenvironment, Immune system, Metastasis and Immunotherapy. His Metastasis study combines topics in areas such as Cancer cell, Warburg effect, Stromal cell and Mitophagy.
His studies deal with areas such as Reprogramming, Transcription factor, Cohesin, Induced pluripotent stem cell and Regulation of gene expression as well as Cell biology. His study with Gene involves better knowledge in Genetics. His Epigenetics research integrates issues from Histone, Methylation, Signal transduction and DNA methylation.
Aristotelis Tsirigos mostly deals with Cancer research, Epigenetics, Cell biology, Chromatin and Immunotherapy. Aristotelis Tsirigos combines subjects such as Cell, Cytotoxic T cell, Metastasis and Immune system with his study of Cancer research. Epigenetics is a subfield of Gene that Aristotelis Tsirigos investigates.
His research in Gene intersects with topics in Molecular biology and Tumour heterogeneity. His biological study spans a wide range of topics, including CTCF, Transcription factor, Cohesin, Induced pluripotent stem cell and Regulation of gene expression. The various areas that Aristotelis Tsirigos examines in his Chromatin study include Enhancer, Mitosis and Stem cell.
The scientist’s investigation covers issues in Cell biology, Cancer research, Epigenetics, Regulation of gene expression and Immunotherapy. His Cell biology research is multidisciplinary, incorporating perspectives in Exon skipping and Chromatin, Post-translational regulation, Gene, Cohesin. In his research, Aristotelis Tsirigos undertakes multidisciplinary study on Cancer research and B-cell acute lymphoblastic leukemia.
His study focuses on the intersection of Epigenetics and fields such as CTCF with connections in the field of DNA methylation, Genomic organization, Genome, Function and DECIPHER. His Regulation of gene expression research is multidisciplinary, incorporating elements of Ubiquitin, Ubiquitin ligase, Pancreatic cancer, Cancer cell and Nucleosome. Aristotelis Tsirigos interconnects Tumor microenvironment, Lung cancer, Autoimmunity and CRISPR in the investigation of issues within Immunotherapy.
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Dynamic changes in the human methylome during differentiation
Louise Laurent;Eleanor Wong;Guoliang Li;Tien Huynh.
Genome Research (2010)
DNA methylation-based classification of central nervous system tumours
David Capper;David Capper;David Capper;David T. W. Jones;Martin Sill;Volker Hovestadt.
Classification and mutation prediction from non-small cell lung cancer histopathology images using deep learning.
Nicolas Coudray;Paolo Santiago Ocampo;Theodore Sakellaropoulos;Navneet Narula.
Nature Medicine (2018)
Accurate phylogenetic classification of variable-length DNA fragments
Alice Carolyn McHardy;Héctor García Martín;Aristotelis Tsirigos;Philip Hugenholtz.
Nature Methods (2007)
Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
Gloria Bonuccelli;Aristotelis Tsirigos;Diana Whitaker-Menezes;Stephanos Pavlides.
Cell Cycle (2010)
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
Panagiotis Ntziachristos;Panagiotis Ntziachristos;Aristotelis Tsirigos;Pieter Van Vlierberghe;Jelena Nedjic.
Nature Medicine (2012)
Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia
Thomas Trimarchi;Thomas Trimarchi;Erhan Bilal;Panagiotis Ntziachristos;Panagiotis Ntziachristos;Giulia Fabbri.
Multipath routing in the presence of frequent topological changes
A. Tsirigos;Z.J. Haas.
IEEE Communications Magazine (2001)
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression
Luisa Cimmino;Igor Dolgalev;Yubao Wang;Akihide Yoshimi.
Ketones and lactate increase cancer cell “stemness”, driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via metabolo-genomics
Ubaldo E. Martinez-Outschoorn;Marco Prisco;Adam Ertel;Aristotelis Tsirigos.
Cell Cycle (2011)
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