D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 41 Citations 9,978 107 World Ranking 15647 National Ranking 6512

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His primary areas of investigation include Metastasis, Cell biology, Cancer research, Cancer cell and Mitophagy. His Metastasis study integrates concerns from other disciplines, such as KEAP1, Lung cancer and Ubiquitin ligase. His Cancer research research integrates issues from Haematopoiesis, Ubiquitin, NFE2L2, Transcription factor and Epigenetics.

His work in Epigenetics addresses issues such as Histone, which are connected to fields such as Gene silencing. His Cancer cell research includes themes of Tumor microenvironment and Cancer stem cell. His Mitophagy research is multidisciplinary, relying on both Reverse Warburg effect, Warburg effect and Stromal cell.

His most cited work include:

  • Dynamic changes in the human methylome during differentiation (803 citations)
  • DNA methylation-based classification of central nervous system tumours (733 citations)
  • Classification and mutation prediction from non-small cell lung cancer histopathology images using deep learning. (656 citations)

What are the main themes of his work throughout his whole career to date?

Aristotelis Tsirigos mainly investigates Cancer research, Cell biology, Chromatin, Gene and Epigenetics. The Cancer research study combines topics in areas such as Cancer, Tumor microenvironment, Immune system, Metastasis and Immunotherapy. His Metastasis study combines topics in areas such as Cancer cell, Warburg effect, Stromal cell and Mitophagy.

His studies deal with areas such as Reprogramming, Transcription factor, Cohesin, Induced pluripotent stem cell and Regulation of gene expression as well as Cell biology. His study with Gene involves better knowledge in Genetics. His Epigenetics research integrates issues from Histone, Methylation, Signal transduction and DNA methylation.

He most often published in these fields:

  • Cancer research (31.82%)
  • Cell biology (25.76%)
  • Chromatin (17.17%)

What were the highlights of his more recent work (between 2019-2021)?

  • Cancer research (31.82%)
  • Epigenetics (15.15%)
  • Cell biology (25.76%)

In recent papers he was focusing on the following fields of study:

Aristotelis Tsirigos mostly deals with Cancer research, Epigenetics, Cell biology, Chromatin and Immunotherapy. Aristotelis Tsirigos combines subjects such as Cell, Cytotoxic T cell, Metastasis and Immune system with his study of Cancer research. Epigenetics is a subfield of Gene that Aristotelis Tsirigos investigates.

His research in Gene intersects with topics in Molecular biology and Tumour heterogeneity. His biological study spans a wide range of topics, including CTCF, Transcription factor, Cohesin, Induced pluripotent stem cell and Regulation of gene expression. The various areas that Aristotelis Tsirigos examines in his Chromatin study include Enhancer, Mitosis and Stem cell.

Between 2019 and 2021, his most popular works were:

  • Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis. (49 citations)
  • In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma (33 citations)
  • Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia. (27 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

The scientist’s investigation covers issues in Cell biology, Cancer research, Epigenetics, Regulation of gene expression and Immunotherapy. His Cell biology research is multidisciplinary, incorporating perspectives in Exon skipping and Chromatin, Post-translational regulation, Gene, Cohesin. In his research, Aristotelis Tsirigos undertakes multidisciplinary study on Cancer research and B-cell acute lymphoblastic leukemia.

His study focuses on the intersection of Epigenetics and fields such as CTCF with connections in the field of DNA methylation, Genomic organization, Genome, Function and DECIPHER. His Regulation of gene expression research is multidisciplinary, incorporating elements of Ubiquitin, Ubiquitin ligase, Pancreatic cancer, Cancer cell and Nucleosome. Aristotelis Tsirigos interconnects Tumor microenvironment, Lung cancer, Autoimmunity and CRISPR in the investigation of issues within Immunotherapy.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Dynamic changes in the human methylome during differentiation

Louise Laurent;Eleanor Wong;Guoliang Li;Tien Huynh.
Genome Research (2010)

1064 Citations

DNA methylation-based classification of central nervous system tumours

David Capper;David Capper;David Capper;David T. W. Jones;Martin Sill;Volker Hovestadt.
Nature (2018)

860 Citations

Classification and mutation prediction from non-small cell lung cancer histopathology images using deep learning.

Nicolas Coudray;Paolo Santiago Ocampo;Theodore Sakellaropoulos;Navneet Narula.
Nature Medicine (2018)

753 Citations

Accurate phylogenetic classification of variable-length DNA fragments

Alice Carolyn McHardy;Héctor García Martín;Aristotelis Tsirigos;Philip Hugenholtz.
Nature Methods (2007)

568 Citations

Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

Gloria Bonuccelli;Aristotelis Tsirigos;Diana Whitaker-Menezes;Stephanos Pavlides.
Cell Cycle (2010)

539 Citations

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

Panagiotis Ntziachristos;Panagiotis Ntziachristos;Aristotelis Tsirigos;Pieter Van Vlierberghe;Jelena Nedjic.
Nature Medicine (2012)

457 Citations

Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia

Thomas Trimarchi;Thomas Trimarchi;Erhan Bilal;Panagiotis Ntziachristos;Panagiotis Ntziachristos;Giulia Fabbri.
Cell (2014)

379 Citations

Multipath routing in the presence of frequent topological changes

A. Tsirigos;Z.J. Haas.
IEEE Communications Magazine (2001)

356 Citations

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Luisa Cimmino;Igor Dolgalev;Yubao Wang;Akihide Yoshimi.
Cell (2017)

344 Citations

Ketones and lactate increase cancer cell “stemness”, driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via metabolo-genomics

Ubaldo E. Martinez-Outschoorn;Marco Prisco;Adam Ertel;Aristotelis Tsirigos.
Cell Cycle (2011)

314 Citations

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