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Jeffrey A. Pfefferkorn

Jeffrey A. Pfefferkorn

Pfizer (United States)
United States

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Chemistry 41 17774 16074 4339 3574 101 6065

Jeffrey A. Pfefferkorn publications per year

The chart shows the history of publications by Jeffrey A. Pfefferkorn between 1983 and 2022, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Jeffrey A. Pfefferkorn published across 40 years, from 1983 to 2022, averaging 2.9 papers a year. Output peaked at 14 publications in 2000. 4 of the 116 publications appeared in the last two years.

No. of publications
5 10
Bar chart. Horizontal axis: year, 1983 to 2022. Vertical axis: number of publications, 0 to 14. Peak 14 publications in 2000. 1983: 1 publication 1984: 0 publications 1985: 0 publications 1986: 0 publications 1987: 0 publications 1988: 0 publications 1989: 0 publications 1990: 0 publications 1991: 0 publications 1992: 0 publications 1993: 0 publications 1994: 0 publications 1995: 0 publications 1996: 0 publications 1997: 3 publications 1998: 9 publications 1999: 7 publications 2000: 14 publications 2001: 5 publications 2002: 4 publications 2003: 1 publication 2004: 0 publications 2005: 4 publications 2006: 1 publication 2007: 7 publications 2008: 6 publications 2009: 5 publications 2010: 1 publication 2011: 4 publications 2012: 11 publications 2013: 6 publications 2014: 6 publications 2015: 3 publications 2016: 2 publications 2017: 2 publications 2018: 1 publication 2019: 4 publications 2020: 5 publications 2021: 3 publications 2022: 1 publication
1983 2022

116 publications in total across all disciplines

View publications per year as a table
Jeffrey A. Pfefferkorn: publications per year, 1983 to 2022
Year Publications
1983 1
1984 0
1985 0
1986 0
1987 0
1988 0
1989 0
1990 0
1991 0
1992 0
1993 0
1994 0
1995 0
1996 0
1997 3
1998 9
1999 7
2000 14
2001 5
2002 4
2003 1
2004 0
2005 4
2006 1
2007 7
2008 6
2009 5
2010 1
2011 4
2012 11
2013 6
2014 6
2015 3
2016 2
2017 2
2018 1
2019 4
2020 5
2021 3
2022 1
Total 116
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Jeffrey A. Pfefferkorn publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Jeffrey A. Pfefferkorn sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 101–120 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 101 publications — 2nd percentile

2% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623 101
121–140 918
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979
281–300 939
301–320 764
321–340 643
341–360 628
361–380 522
381–400 459
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
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Jeffrey A. Pfefferkorn D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jeffrey A. Pfefferkorn sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 40–41 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 41 D-Index — 2nd percentile

2% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289 41
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051
58–59 930
60–61 882
62–63 834
64–65 731
66–67 775
68–69 683
70–71 646
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235
90–91 185
92–93 192
94–95 155
96–97 163
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
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Overview

Jeffrey A. Pfefferkorn is affiliated with Pfizer in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research focuses on multiple aspects of liver disease, metabolism, and molecular mechanisms relevant to therapy and diagnosis.

The main topics of their work include:

  • Liver Disease Diagnosis and Treatment
  • Peroxisome Proliferator-Activated Receptors
  • Drug Transport and Resistance Mechanisms
  • Diet, Metabolism, and Disease
  • Diet and metabolism studies
  • Pancreatic function and diabetes
  • Hepatitis C virus research

Pfefferkorn has published research in several key scientific journals. Frequent publication venues for their work include:

  • Journal of Medicinal Chemistry
  • Nature Medicine
  • Cellular and Molecular Gastroenterology and Hepatology
  • Molecular Metabolism
  • Nature Metabolism

Recent papers authored or co-authored by Pfefferkorn encompass significant topics related to metabolic disorders and liver disease. These include:

  • ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a trials, 2021, Nature Medicine
  • Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems, 2020, Cellular and Molecular Gastroenterology and Hepatology
  • Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction, 2021, Molecular Metabolism
  • Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose, 2020, Journal of Medicinal Chemistry
  • De novo lipogenesis is essential for platelet production in humans, 2020, Nature Metabolism

The scientist frequently collaborates with other researchers in the field. Notable frequent co-authors include:

  • Trenton T. Ross
  • Collin Crowley
  • William P. Esler
  • Gregory J. Tesz
  • Matthew Dowling

Pfefferkorn's research covers a range of subfields such as Epidemiology, Molecular Biology, Oncology, Endocrinology, Diabetes and Metabolism, and Physiology. This diverse involvement reflects the interdisciplinary nature of their work spanning disease mechanisms, metabolic regulation, and therapeutic development.

Best Publications

  • Natural Product-like Combinatorial Libraries Based on Privileged Structures. 1. General Principles and Solid-Phase Synthesis of Benzopyrans

    K. C. Nicolaou;J. A. Pfefferkorn;A. J. Roecker;G.-Q. Cao

  • Natural Product-like Combinatorial Libraries Based on Privileged Structures. 2. Construction of a 10 000-Membered Benzopyran Library by Directed Split-and-Pool Chemistry Using NanoKans and Optical Encoding

    K. C. Nicolaou;J. A. Pfefferkorn;H. J. Mitchell;A. J. Roecker

  • Natural Product-like Combinatorial Libraries Based on Privileged Structures. 3. The “Libraries from Libraries” Principle for Diversity Enhancement of Benzopyran Libraries

    K. C. Nicolaou;J. A. Pfefferkorn;S. Barluenga;H. J. Mitchell

  • SOLID AND SOLUTION PHASE SYNTHESIS AND BIOLOGICAL EVALUATION OF COMBINATORIAL SARCODICTYIN LIBRARIES

    K. C. Nicolaou;Nicolas Charles Winssinger;D. Vourloumis;T. Ohshima

  • Selenium‐Based Solid‐Phase Synthesis of Benzopyrans I: Applications to Combinatorial Synthesis of Natural Products

    K. C. Nicolaou;Jeffrey A. Pfefferkorn;Guo-Qiang Cao

  • Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus.

    Jeffrey A. Pfefferkorn;Angel Guzman-Perez;John Litchfield;Robert Aiello

  • Total Synthesis of Eleutherobin

    K. C. Nicolaou;K. C. Nicolaou;Floris van Delft;Floris van Delft;Takashi Ohshima;Takashi Ohshima;Dionisios Vourloumis;Dionisios Vourloumis

  • A Novel Strategy for the Solid-Phase Synthesis of Substituted Indolines

    K. C. Nicolaou;A. J. Roecker;and Jeffrey A. Pfefferkorn;Gou-Qiang Cao

  • Total Synthesis of Eleutherobin and Eleuthosides A and B

    K. C. Nicolaou;T. Ohshima;S. Hosokawa;F. L. Van Delft

  • Selenium-Based Solid-Phase Synthesis of Benzopyrans II: Applications to Combinatorial Synthesis of Medicinally Relevant Small Organic Molecules.

    K. C. Nicolaou;Guo-Qiang Cao;Jeffrey A. Pfefferkorn

  • Glycomimetic ligands for the human asialoglycoprotein receptor.

    Sreeman K Mamidyala;Sanjay Dutta;Boris A Chrunyk;Cathy Préville

  • SYNTHESIS OF THE TRICYCLIC CORE OF ELEUTHEROBIN AND SARCODICTYINS AND TOTAL SYNTHESIS OF SARCODICTYIN A

    K. C. Nicolau;J. Y. Xu;S. Kim;T. Ohshima

  • Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.

    Jessica E. C. Jones;William P. Esler;Rushi Patel;Adhiraj Lanba

  • Combinatorial synthesis through disulfide exchange: discovery of potent psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA).

    K. C. Nicolaou;Robert Hughes;Jeffrey A. Pfefferkorn;Sofia Barluenga

  • Total Synthesis of Sarcodictyins A and B

    K. C. Nicolaou;J. Y. Xu;S. Kim;J. Pfefferkorn

  • Solution and Solid‐Phase Synthesis of Functionalized 3‐Arylbenzofurans by a Novel Cyclofragmentation – Release Pathway

    K. C. Nicolaou;Scott A. Snyder;Antony Bigot;Jeffrey A. Pfefferkorn

  • Combinatorial synthesis of novel and potent inhibitors of NADH:ubiquinone oxidoreductase

    KC Nicolaou;KC Nicolaou;JA Pfefferkorn;F Schuler;AJ Roecker

  • Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)

    Kentaro Futatsugi;Daniel W. Kung;Suvi T. M. Orr;Shawn Cabral

  • Synthesis of the Fully Functionalized Bicyclic Core of Garsubellin A

    K. C. Nicolaou;J. A. Pfefferkorn;and S. Kim;H. X. Wei

  • Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid

    Jeffrey A. Pfefferkorn;Richard Nugent;Rebecca J. Gross;Meredith Greene

  • A facile method for the solution and solid-phase synthesis of substituted [3.3.1] bicycles.

    K. C. Nicolaou;Jeffrey A. Pfefferkorn;Guo-Qiang Cao;Sanghee Kim

  • Total synthesis of sarcodictyins A and B: Solid- and solution-phase synthesis and biological evaluation of combinatorial sarcodictyin libraries

    K. C. Nicolaou;N. Winssinger;D. Vourloumis;T. Ohshima

Frequent Co-Authors

K. C. Nicolaou
K. C. Nicolaou Rice University
Scott D. Larsen
Scott D. Larsen University of Michigan–Ann Arbor
Takashi Ohshima
Takashi Ohshima Kyushu University
Sanghee Kim
Sanghee Kim Seoul National University
Dionisios Vourloumis
Dionisios Vourloumis Demokritos National Centre for Scientific Research
Amit S. Kalgutkar
Amit S. Kalgutkar Pfizer (United States)
Nicolas Winssinger
Nicolas Winssinger University of Geneva
Spiros Liras
Spiros Liras University of California, San Francisco
Li Di
Li Di Pfizer (United States)
David Price
David Price University of Aberdeen

External Links

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Publications: 55

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Publications: 13

Li Di

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Publications: 10

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Publications: 10

Erwin G. Van Meir

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Ming-Wei Wang

Ming-Wei Wang

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Publications: 10

Cesare Gennari

Cesare Gennari

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Publications: 10

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Publications: 9

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Publications: 9

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