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Chemistry

D-Index
45
Citations
8313
World Ranking
16354
National Ranking
74

Overview

Dionisios Vourloumis is affiliated with the Demokritos National Centre for Scientific Research in Greece. Their research spans fields including Medicine, Chemistry, and Biochemistry, Genetics and Molecular Biology, with particular focus on Molecular Biology, Organic Chemistry, Materials Chemistry, Oncology, and Infectious Diseases.

Their recent scholarly contributions include publications in several peer-reviewed journals:

  • Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues (2020), published in Journal of the American Chemical Society
  • Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of Bestatin (2022), published in Journal of Medicinal Chemistry
  • Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis (2021), published in The Journal of Organic Chemistry
  • CCDC 2011802: Experimental Crystal Structure Determination (2020), published in The Cambridge Structural Database

Frequent co-authors collaborating with Dionisios Vourloumis include:

  • K. C. Nicolaou
  • Stefan Munneke
  • Christine Gu
  • Hetal Sarvaiaya
  • Joseph Sandoval

The scientist's research addresses topics such as:

  • Synthetic Organic Chemistry Methods
  • Chemical Synthesis and Analysis
  • Cancer therapeutics and mechanisms
  • Peptidase Inhibition and Analysis
  • Antifungal resistance and susceptibility
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Synthesis and biological activity

Publications by Dionisios Vourloumis have appeared in prominent venues, including:

  • Journal of the American Chemical Society
  • Journal of Medicinal Chemistry
  • The Journal of Organic Chemistry
  • The Cambridge Structural Database

Best Publications

  • The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

    K. C. Nicolaou;Dionisios Vourloumis;Nicolas Charles Winssinger;Phil S. Baran

  • Synthesis of epothilones A and B in solid and solution phase

    K. C. Nicolaou;Nicolas Charles Winssinger;Nicolas Charles Winssinger;J. Pastor;J. Pastor;S. Ninkovic;S. Ninkovic

  • Chemical Biology of Epothilones

    K. C. Nicolaou;Frank Roschangar;Dionisios Vourloumis

  • Total Syntheses of Epothilones A and B via a Macrolactonization-Based Strategy

    K. C. Nicolaou;S. Ninkovic;F. Sarabia;D. Vourloumis

  • Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells†

    K. C. Nicolaou;K. C. Nicolaou;Dionisios Vourloumis;Dionisios Vourloumis;Tianhu Li;Tianhu Li;Joaquin Pastor;Joaquin Pastor

  • Total Synthesis of Epothilone A: The Olefin Metathesis Approach

    Zhen Yang;Yun He;Dionisios Vourloumis;Hans Vallberg

  • The Olefin Metathesis Approach to Epothilone A and Its Analogues

    K. C. Nicolaou;Y. He;D. Vourloumis;H. Vallberg

  • Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes.

    Vasilis P. Androutsopoulos;Athanasios Papakyriakou;Dionisios Vourloumis;Aristidis M. Tsatsakis

  • The coral-derived natural products eleutherobin and sarcodictyins A and B: effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site.

    Ernest Hamel;Dan L. Sackett;Dionisios Vourloumis;K. C. Nicolaou

  • SOLID AND SOLUTION PHASE SYNTHESIS AND BIOLOGICAL EVALUATION OF COMBINATORIAL SARCODICTYIN LIBRARIES

    K. C. Nicolaou;Nicolas Charles Winssinger;D. Vourloumis;T. Ohshima

  • Der Stand der Totalsynthese zu Beginn des 21. Jahrhunderts

    K. C. Nicolaou;Dionisios Vourloumis;Nicolas Winssinger;Phil S. Baran

  • An Approach to Epothilones Based on Olefin Metathesis

    K. C. Nicolaou;Yun He;Dionisios Vourloumis;Hans Vallberg

  • Novel copper(II) complex of N-propyl-norfloxacin and 1,10-phenanthroline with enhanced antileukemic and DNA nuclease activities.

    Maria E. Katsarou;Eleni K. Efthimiadou;George Psomas;Alexandra Karaliota

  • Total synthesis of epothilone E and related side-chain modified analogues via a Stille coupling based strategy.

    K.C. Nicolaou;N.P. King;N.P. King;M.R.V. Finlay;M.R.V. Finlay;Y. He;Y. He

  • Monitoring Molecular Recognition of the Ribosomal Decoding Site

    Sarah Shandrick;Qiang Zhao;Qing Han;Benjamin K. Ayida

  • Total Synthesis of Eleutherobin

    K. C. Nicolaou;K. C. Nicolaou;Floris van Delft;Floris van Delft;Takashi Ohshima;Takashi Ohshima;Dionisios Vourloumis;Dionisios Vourloumis

  • Total Synthesis of Eleutherobin and Eleuthosides A and B

    K. C. Nicolaou;T. Ohshima;S. Hosokawa;F. L. Van Delft

  • Chemie und Biologie der Epothilone

    Kyriacos C. Nicolaou;Frank Roschangar;Dionisios Vourloumis

  • Synthesis and Biopharmaceutical Evaluation of Imatinib Analogues Featuring Unusual Structural Motifs

    Kyriacos C. Nicolaou;Dionisios Vourloumis;Sotirios Totokotsopoulos;Athanasios Papakyriakou

  • Total Synthesis of Epothilone E and Analogues with Modified Side Chains through the Stille Coupling Reaction

    K. C. Nicolaou;Yun He;Frank Roschangar;N. Paul King

  • Total Synthesis of Apoptolidin: Completion of the Synthesis and Analogue Synthesis and Evaluation

    K. C. Nicolaou;Yiwei Li;Kazuyuki Sugita;Holger Monenschein

Frequent Co-Authors

K. C. Nicolaou
K. C. Nicolaou Rice University
Yun He
Yun He Chongqing University
Nicolas Winssinger
Nicolas Winssinger University of Geneva
Takashi Ohshima
Takashi Ohshima Kyushu University
Sanghee Kim
Sanghee Kim Seoul National University
Zhen Yang
Zhen Yang Peking University
Thomas Hermann
Thomas Hermann University of California, San Diego
Jeffrey A. Pfefferkorn
Jeffrey A. Pfefferkorn Pfizer (United States)
Sofia Barluenga
Sofia Barluenga University of Geneva
Ernest Hamel
Ernest Hamel National Institutes of Health

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