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Nicolas Winssinger

Nicolas Winssinger

D-Index & Metrics

Chemistry

D-Index
69
Citations
14719
World Ranking
6306
National Ranking
128

Overview

Nicolas Winssinger is affiliated with the University of Geneva in Switzerland. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Organic Chemistry, Cell Biology, Infectious Diseases, and Biomedical Engineering as notable subfields.

Their work covers a range of topics including advanced biosensing and bioanalysis techniques, chemical synthesis and analysis, DNA and nucleic acid chemistry, microtubule and mitosis dynamics, click chemistry and applications, SARS-CoV-2 and COVID-19 research, and monoclonal and polyclonal antibodies research.

Frequent coauthors in Nicolas Winssinger's publications include Sofía Barluenga, Lluc Farrera-Soler, Jean-Pierre Daguer, Simona Angerani, and Eric Lindberg. These collaborations have contributed to the body of work published mainly in venues such as Zenodo (CERN European Organization for Nuclear Research), OPAL (Open@LaTrobe, La Trobe University), Journal of the American Chemical Society, Angewandte Chemie International Edition, and bioRxiv (Cold Spring Harbor Laboratory).

Recent selected papers authored or coauthored by Nicolas Winssinger are:

  • Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma, 2020, PLoS ONE
  • Oligonucleotide Phosphorothioates Enter Cells by Thiol-Mediated Uptake, 2021, Angewandte Chemie International Edition
  • DNA-Encoded Libraries: Towards Harnessing their Full Power with Darwinian Evolution, 2022, Angewandte Chemie International Edition
  • Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks, 2020, Journal of the American Chemical Society
  • A mating mechanism to generate diversity for the Darwinian selection of DNA-encoded synthetic molecules, 2021, Nature Chemistry

Best Publications

  • Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics.

    K. C. Nicolaou;Christopher N. C. Boddy;Stefan Bräse;Nicolas Charles Winssinger

  • The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

    K. C. Nicolaou;Dionisios Vourloumis;Nicolas Charles Winssinger;Phil S. Baran

  • Synthesis of epothilones A and B in solid and solution phase

    K. C. Nicolaou;Nicolas Charles Winssinger;Nicolas Charles Winssinger;J. Pastor;J. Pastor;S. Ninkovic;S. Ninkovic

  • Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells†

    K. C. Nicolaou;K. C. Nicolaou;Dionisios Vourloumis;Dionisios Vourloumis;Tianhu Li;Tianhu Li;Joaquin Pastor;Joaquin Pastor

  • A General and Highly Efficient Solid Phase Synthesis of Oligosaccharides. Total Synthesis of a Heptasaccharide Phytoalexin Elicitor (HPE)

    K. C. Nicolaou;Nicolas Charles Winssinger;Joaquín Pastor;Frederik DeRoose

  • Chemistry and biology of resorcylic acid lactones

    Nicolas Charles Winssinger;Sofia Barluenga

  • Profiling protein function with small molecule microarrays

    Nicolas Charles Winssinger;Scott Ficarro;Peter G. Schultz;Jennifer L. Harris

  • Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors.

    Emeline Leproult;Sofia Barluenga;Dino Moras;Jean-Marie Wurtz

  • Total Synthesis of Vancomycin

    K. C. Nicolaou;Helen J. Mitchell;Nareshkumar F. Jain;Nicolas Charles Winssinger

  • SOLID AND SOLUTION PHASE SYNTHESIS AND BIOLOGICAL EVALUATION OF COMBINATORIAL SARCODICTYIN LIBRARIES

    K. C. Nicolaou;Nicolas Charles Winssinger;D. Vourloumis;T. Ohshima

  • Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics.

    Jacques Saarbach;Pramod Madhavrao Sabale;Nicolas Winssinger

  • Der Stand der Totalsynthese zu Beginn des 21. Jahrhunderts

    K. C. Nicolaou;Dionisios Vourloumis;Nicolas Winssinger;Phil S. Baran

  • Reactions Templated by Nucleic Acids: More Ways to Translate Oligonucleotide‐Based Instructions into Emerging Function

    Katarzyna Gorska;Nicolas Winssinger;Nicolas Winssinger

  • Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria

    K. C. Nicolaou;Robert Hughes;Suk Young Cho;Nicolas Charles Winssinger

  • Chemie, Biologie und medizinische Anwendungen der Glycopeptid-Antibiotika

    K. C. Nicolaou;Christopher N. C. Boddy;Stefan Bräse;Nicolas Winssinger

  • The Molecular Chaperone Hsp90α Is Required for Meiotic Progression of Spermatocytes beyond Pachytene in the Mouse

    Iwona Grad;Christopher Cederroth;Joël Jonathan Walicki;Corinne Grey

  • Development of a functionalized xenon biosensor.

    Megan M. Spence;E. Janette Ruiz;Seth M. Rubin;Thomas J. Lowery

  • Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes.

    Zbigniew Pianowski;Katarzyna Gorska;Laurence Oswald;Christoph A. Merten

  • Polymer-supported selenium reagents for organic synthesis

    K. C. Nicolaou;Joaquín Pastor;Sofia Barluenga;Nicolas Charles Winssinger

  • DNA‐Templated Homo‐ and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV

    Katarzyna Gorska;Kuo-Ting Huang;Olivier Chaloin;Nicolas Charles Winssinger

  • Synthesis and biological evaluation of vancomycin dimers with potent activity against vancomycin-resistant bacteria: target-accelerated combinatorial synthesis.

    K. C. Nicolaou;Robert Hughes;Suk Young Cho;Nicolas Charles Winssinger

Frequent Co-Authors

Sofia Barluenga
Sofia Barluenga University of Geneva
K. C. Nicolaou
K. C. Nicolaou Rice University
Dionisios Vourloumis
Dionisios Vourloumis Demokritos National Centre for Scientific Research
Takashi Ohshima
Takashi Ohshima Kyushu University
Yun He
Yun He Chongqing University
Sanghee Kim
Sanghee Kim Seoul National University
Martin Karplus
Martin Karplus Harvard University
Peter G. Schultz
Peter G. Schultz Scripps Research Institute
Jeffrey A. Pfefferkorn
Jeffrey A. Pfefferkorn Pfizer (United States)
Howard Riezman
Howard Riezman University of Geneva

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