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D-Index & Metrics

Chemistry

D-Index
51
Citations
8858
World Ranking
14000
National Ranking
2169

Overview

Yun He is affiliated with Chongqing University in China and has contributed extensively to scientific research in fields including Biochemistry, Genetics and Molecular Biology, Chemistry, and Medicine. Their work spans various subfields such as Molecular Biology, Organic Chemistry, Cancer Research, Infectious Diseases, and Microbiology.

Their research covers diverse topics with significant publications related to Catalytic C-H Functionalization Methods, Catalytic Cross-Coupling Reactions, Cancer, Hypoxia, and Metabolism, Antimicrobial Peptides and Activities, Sulfur-Based Synthesis Techniques, Antibiotic Resistance in Bacteria, and Cancer therapeutics and mechanisms.

Yun He has frequently co-authored with several colleagues, including:

  • Feng Zhang
  • Zhengli Liu
  • Jian Guo
  • Shaolin Zhang
  • Haibo Peng

Their recent publications include:

  • Strategies and progresses for enhancing targeted antibiotic delivery, 2022, Advanced Drug Delivery Reviews
  • Eradicating intracellular MRSA via targeted delivery of lysostaphin and vancomycin with mannose-modified exosomes, 2020, Journal of Controlled Release
  • Exosomal hsa-miR-21-5p is a biomarker for breast cancer diagnosis, 2021, PeerJ
  • A Reactive Oxygen Species (ROS) Activated Hydrogen Sulfide (H2S) Donor with Self-Reporting Fluorescence, 2020, ACS Sensors
  • Experimental and Computational Studies of the Iron-Catalyzed Selective and Controllable Defluorosilylation of Unactivated Aliphatic gem-Difluoroalkenes, 2021, Angewandte Chemie International Edition

The venues where Yun He frequently publishes include:

  • European Journal of Medicinal Chemistry
  • Organic Letters
  • Journal of Controlled Release
  • Journal of Medicinal Chemistry
  • Chemical Communications

Best Publications

  • Synthesis of epothilones A and B in solid and solution phase

    K. C. Nicolaou;Nicolas Charles Winssinger;Nicolas Charles Winssinger;J. Pastor;J. Pastor;S. Ninkovic;S. Ninkovic

  • Total Syntheses of Epothilones A and B via a Macrolactonization-Based Strategy

    K. C. Nicolaou;S. Ninkovic;F. Sarabia;D. Vourloumis

  • Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells†

    K. C. Nicolaou;K. C. Nicolaou;Dionisios Vourloumis;Dionisios Vourloumis;Tianhu Li;Tianhu Li;Joaquin Pastor;Joaquin Pastor

  • Total Synthesis of Epothilone A: The Olefin Metathesis Approach

    Zhen Yang;Yun He;Dionisios Vourloumis;Hans Vallberg

  • The Olefin Metathesis Approach to Epothilone A and Its Analogues

    K. C. Nicolaou;Y. He;D. Vourloumis;H. Vallberg

  • Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2.

    Tao Jiang;Kelli L. Kuhen;Karen Wolff;Hong Yin

  • An Approach to Epothilones Based on Olefin Metathesis

    K. C. Nicolaou;Yun He;Dionisios Vourloumis;Hans Vallberg

  • Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors.

    Mark W. Holladay;James T. Wasicak;Nan-Horng Lin;Yun He

  • Total synthesis of epothilone E and related side-chain modified analogues via a Stille coupling based strategy.

    K.C. Nicolaou;N.P. King;N.P. King;M.R.V. Finlay;M.R.V. Finlay;Y. He;Y. He

  • Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 1.

    Ha-Soon Choi;Zhicheng Wang;Wendy Richmond;Xiaohui He

  • 2-piperidin-4-yl-benzimidazoles with broad spectrum antibacterial activities.

    Yun He;Baogen Wu;Jun Yang;Dale Robinson

  • Compounds and compositions as inhibitors of cannabinoid receptor 1 activity

    Hong Liu;Xiaohui He;Ha-Soon Choi;Kunyong Yang

  • Synthesis and biological evaluations of novel benzimidazoles as potential antibacterial agents.

    Yun He;Jun Yang;Baogen Wu;Lisa Risen

  • Total Synthesis of the CP Molecules CP-263,114 and CP-225,917- Part 1: Synthesis of Key Intermediates and Intelligence Gathering.

    K. C. Nicolaou;Phil S. Baran;Yong-Li Zhong;Ha-Soon Choi

  • Total Synthesis of Epothilone E and Analogues with Modified Side Chains through the Stille Coupling Reaction

    K. C. Nicolaou;Yun He;Frank Roschangar;N. Paul King

  • Design, synthesis, and biological evaluations of novel quinolones as HIV-1 non-nucleoside reverse transcriptase inhibitors

    David Ellis;Kelli L. Kuhen;Beth Anaclerio;Baogen Wu

  • Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: Effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice

    Mark W. Holladay;Hao Bai;Yihong Li;Nan-Horng Lin

  • Total Synthesis of the CP Molecules CP-225,917 and CP-263,114- Part 2: Evolution of the Final Strategy.

    K. C. Nicolaou;Phil S. Baran;Yong-Li Zhong;Kin Chiu Fong

  • Epothilone derivatives and their synthesis and use

    Kyriacos Costa Nicolaou;Nigel Paul King;Maurice Raymond Verschoyle Finlay;Yun He

  • Synthesis and biological properties of C12,13-cyclopropylepothilone A and related epothilones

    K.C. Nicolaou;K.C. Nicolaou;M.Ray V. Finlay;M.Ray V. Finlay;Sacha Ninkovic;Sacha Ninkovic;N.Paul King;N.Paul King

  • Exosome-encapsulated antibiotic against intracellular infections of methicillin-resistant Staphylococcus aureus.

    Xiaohong Yang;Gongming Shi;Jian Guo;Chenhui Wang

Frequent Co-Authors

K. C. Nicolaou
K. C. Nicolaou Rice University
Dionisios Vourloumis
Dionisios Vourloumis Demokritos National Centre for Scientific Research
Phil S. Baran
Phil S. Baran Scripps (United States)
Zhen Yang
Zhen Yang Peking University
Nathanael S. Gray
Nathanael S. Gray Stanford University
Nicolas Winssinger
Nicolas Winssinger University of Geneva
Eric E. Swayze
Eric E. Swayze Ionis Pharmaceuticals (United States)
Ernest Hamel
Ernest Hamel National Institutes of Health
Scott A. Lesley
Scott A. Lesley Genomics Institute of the Novartis Research Foundation
Nicola Tirelli
Nicola Tirelli Italian Institute of Technology

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