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D-Index
75
Citations
19315
World Ranking
4456
National Ranking
328

Overview

Gerhard Höfle is affiliated with the Helmholtz Centre for Infection Research in Germany. Their work is situated within an institution known for its focus on understanding infectious diseases and advancing research in infection biology and related fields.

Although specific publication details such as recent papers, co-authors, or venues are not listed, Höfle's association with the Helmholtz Centre suggests involvement in research pertinent to infection research and microbiology.

No records of book publications, awards, or detailed topics and subfields of study are currently available. However, being associated with a major research center indicates active engagement in scientific investigations typically coordinated within such institutions.

There is no indication of deceased status, and thus the profile reflects an ongoing research career.

Best Publications

  • 4-Dialkylaminopyridines as Highly Active Acylation Catalysts. [New synthetic method (25)]

    Gerhard Höfle;Wolfgang Steglich;Helmut Vorbrüggen

  • Epothilons A and B: antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physico-chemical and biological properties.

    Klaus Gerth;Norbert Bedorf;Gerhard Höfle;Herbert Irschik

  • Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution†

    Gerhard Höfle;Norbert Bedorf;Heinrich Steinmetz;Dietmar Schomburg

  • 4‐Dialkylaminopyridine als hochwirksame Acylierungskatalysatoren

    Gerhard Höfle;Wolfgang Steglich;Helmut Vorbrüggen

  • N,N‐Dimethyl‐4‐pyridinamine, a Very Effective Acylation Catalyst

    Unknown

  • Nucleoside Syntheses, XXIII1) On the Mechanism of Nucleoside Synthesis

    Helmut Vorbrüggen;Gerhard Höfle

  • Tubulysins, new cytostatic peptides from myxobacteria acting on microtubuli. Production, isolation, physico-chemical and biological properties.

    Florenz Sasse;Heinrich Steinmetz;Jurgen Heil;Gerhard Hofle

  • Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase.

    Thorsten Friedrich;Petra Van Heek;Hans Leif;Tomoko Ohnishi

  • New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1.

    Barbara Silakowski;Hans Ulrich Schairer;Heidi Ehret;Brigitte Kunze

  • 4‐Dimethylamino‐pyridin, ein hochwirksamer Acylierungskatalysator

    W. Steglich;G. Höfle

  • The Biosynthesis of the Aromatic Myxobacterial Electron Transport Inhibitor Stigmatellin Is Directed by a Novel Type of Modular Polyketide Synthase

    Nikolaos Gaitatzis;Barbara Silakowski;Brigitte Kunze;Gabriele Nordsiek

  • New natural epothilones from Sorangium cellulosum, strains So ce90/B2 and So ce90/D13: isolation, structure elucidation, and SAR studies.

    Ingo H. Hardt;Heinrich Steinmetz;Klaus Gerth;F. Sasse

  • Isolation, crystal and solution structure determination, and biosynthesis of tubulysins--powerful inhibitors of tubulin polymerization from myxobacteria.

    Heinrich Steinmetz;Nicole Glaser;Eberhardt Herdtweck;Florenz Sasse

  • Apicularens A and B, new cytostatic macrolides from Chondromyces species (myxobacteria): production, physico-chemical and biological properties.

    Brigitte Kunze;Rolf Jansen;Florenz Sasse;Gerhard Höfle

  • The soraphens: a family of novel antifungal compounds from Sorangium cellulosum (Myxobacteria). I. Soraphen A1 alpha: fermentation, isolation, biological properties.

    Klaus Gerth;Norbert Bedorf;Herbert Irschik;Gerhard Höfle

  • 4-Dialkylaminopyridines as Acylation Catalysts; III1. Acylation of Sterically Hindered Alcohols

    Gerhard Höfle;Wolfgang Steglich

  • The aurachins, new quinoline antibiotics from myxobacteria: production, physico-chemical and biological properties.

    Brigitte Kunze;Gerhard Höfle;Hans Reichenbach

  • The sorangicins, novel and powerful inhibitors of eubacterial RNA polymerase isolated from myxobacteria.

    Herbert Irschik;Rolf Jansen;Klaus Gerth;Gerhardt Höfle

  • Chondramides A~D, New Antifungal and Cytostatic Depsipeptides from Chondromyces crocatus(Myxobacteria)Production, Physico-chemical and Biological Properties

    Brigitte Kunze;Rolf Jansen;Florenz Sasse;Gerhard Höfle

  • Structure and biosynthesis of myxochromides S1-3 in Stigmatella aurantiaca: evidence for an iterative bacterial type I polyketide synthase and for module skipping in nonribosomal peptide biosynthesis.

    Silke C. Wenzel;Brigitte Kunze;Gerhard Höfle;Barbara Silakowski

  • The myxopyronins, new inhibitors of bacterial RNA synthesis from Myxococcus fulvus (myxobacterales)

    H. Irschik;K. Gerth;G. Höfle;W. Kohl

Frequent Co-Authors

Hans Reichenbach
Hans Reichenbach University of California, Los Angeles
Rolf Jansen
Rolf Jansen Helmholtz Centre for Infection Research
Klaus Gerth
Klaus Gerth Helmholtz Centre for Infection Research
Wolfgang Steglich
Wolfgang Steglich Ludwig-Maximilians-Universität München
Florenz Sasse
Florenz Sasse Technische Universität Braunschweig
Victor Wray
Victor Wray Heinrich Heine University Düsseldorf
Rolf Müller
Rolf Müller Saarland University
Gerhard Hunsmann
Gerhard Hunsmann University of Göttingen
Dietmar Schomburg
Dietmar Schomburg Technische Universität Braunschweig
Helge B. Bode
Helge B. Bode Goethe University Frankfurt

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