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Thorsten Friedrich

Thorsten Friedrich

D-Index & Metrics

Chemistry

D-Index
55
Citations
10308
World Ranking
12185
National Ranking
898

Biology and Biochemistry

D-Index
56
Citations
10396
World Ranking
14509
National Ranking
1031

Overview

Thorsten Friedrich is affiliated with the University of Freiburg in Germany and has a research focus within the field of Biochemistry, Genetics and Molecular Biology. Their work spans a range of subfields including Molecular Biology, Renewable Energy, Sustainability and the Environment, Cellular and Molecular Neuroscience, Electrochemistry, and Genetics.

The scientist's research covers several key topics, notably:

  • Photosynthetic Processes and Mechanisms
  • Mitochondrial Function and Pathology
  • Metalloenzymes and iron-sulfur proteins
  • Photoreceptor and optogenetics research
  • ATP Synthase and ATPases Research
  • Electrochemical Analysis and Applications
  • Lipid Membrane Structure and Behavior

Their recent publication record includes articles in various notable journals. Some of the more recent papers authored or co-authored by Thorsten Friedrich are:

  • "Quantifying the heterogeneity of macromolecular machines by mass photometry" (2020), published in Nature Communications
  • "Mass Photometry of Membrane Proteins" (2020), published in Chem
  • "Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D" (2021), published in Nature Communications
  • "Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis" (2022), published in Nature Communications
  • "Water-Gated Proton Transfer Dynamics in Respiratory Complex I" (2020), published in Journal of the American Chemical Society

Frequent publication venues for Thorsten Friedrich's work include:

  • Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • FEBS Letters
  • Nature Communications
  • Structure
  • Scientific Reports

Thorsten Friedrich has collaborated frequently with other researchers. Regular co-authors include:

  • Daniel Wohlwend
  • Petra Hellwig
  • Frédéric Melin
  • Johannes Schimpf
  • Iryna Makarchuk

Best Publications

  • The respiratory-chain NADH dehydrogenase (complex I) of mitochondria

    Hanns Weiss;Thorsten Friedrich;Götz Hofhaus;Dagmar Preis

  • The respiratory complex I of bacteria, archaea and eukarya and its module common with membrane-bound multisubunit hydrogenases.

    Thorsten Friedrich;Dierk Scheide

  • The Gene Locus of the Proton-translocating NADH : Ubiquinone Oxidoreductase in Escherichia coli: Organization of the 14 Genes and Relationship Between the Derived Proteins and Subunits of Mitochondrial Complex I

    Uwe Weidner;Stephan Geier;Arne Ptock;Thorsten Friedrich

  • Isolation and Characterization of the Proton-translocating NADH:ubiquinone Oxidoreductase from Escherichia coli

    Hans Leif;Vladimir D. Sled;Vladimir D. Sled;Tomoko Ohnishi;Hanns Weiss

  • The proton-pumping respiratory complex I of bacteria and mitochondria and its homologue in chloroplasts

    Thorsten Friedrich;Klaus Steinmüller;Hanns Weiss

  • Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase.

    Thorsten Friedrich;Petra Van Heek;Hans Leif;Tomoko Ohnishi

  • Consistent structure between bacterial and mitochondrial NADH:Ubiquinone oxidoreductase (Complex I)

    Vincent Guénebaut;Angela Schlitt;Hanns Weiss;Kevin Leonard

  • Modular evolution of the respiratory NADH:ubiquinone oxidoreductase and the origin of its modules.

    Thorsten Friedrich;Hanns Weiss

  • An anaerobic mitochondrion that produces hydrogen

    Brigitte Boxma;Rob M. de Graaf;Georg W.M. van der Staay;Theo A. van Alen

  • THE NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) FROM ESCHERICHIA COLI

    Thorsten Friedrich

  • Complex I: A Chimaera of a Redox and Conformation-Driven Proton Pump?

    Thorsten Friedrich

  • Quantifying the heterogeneity of macromolecular machines by mass photometry.

    Adar Sonn-Segev;Katarina Belacic;Tatyana Bodrug;Gavin Young

  • A small isoform of NADH:ubiquinone oxidoreductase (complex I) without mitochondrially encoded subunits is made in chloramphenicol-treated Neurospora crassa.

    Thorsten Friedrich;Gotz Hofhaus;Wolfgang Ise;Uwe Nehls

  • The gross structure of the respiratory complex I: a Lego System.

    Thorsten Friedrich;Bettina Böttcher

  • Menaquinone as pool quinone in a purple bacterium

    Barbara Schoepp-Cothenet;Clément Lieutaud;Frauke Baymann;André Verméglio

  • The Escherichia coli NADH:ubiquinone oxidoreductase (complex I) is a primary proton pump but may be capable of secondary sodium antiport.

    Stefan Stolpe;Thorsten Friedrich

  • Identification and characterization of the tungsten-containing class of benzoyl-coenzyme A reductases

    Johannes W. Kung;Claudia Löffler;Katerina Dörner;Dimitri Heintz

  • Mutational analysis of residues forming hydrogen bonds in the Rieske [2Fe‐2S] cluster of the cytochrome bc1 complex in Paracoccus denitrificans

    Thomas Schröter;Oliver M. Hatzfeld;Sabine Gemeinhardt;Marcus Korn

  • A novel, enzymatically active conformation of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I).

    Bettina Böttcher;Dierk Scheide;Micaela Hesterberg;Luitgard Nagel-Steger

  • Characterization of assembly intermediates of NADH:ubiquinone oxidoreductase (complex I) accumulated in Neurospora mitochondria by gene disruption.

    Uwe Nehls;Thorsten Friedrich;Andreas Schmiede;Tomoko Ohnishi

Frequent Co-Authors

Hanns Weiss
Hanns Weiss Heinrich Heine University Düsseldorf
Oliver Einsle
Oliver Einsle University of Freiburg
Tomoko Ohnishi
Tomoko Ohnishi University of Pennsylvania
Simon de Vries
Simon de Vries Delft University of Technology
Benedikt Brors
Benedikt Brors German Cancer Research Center
Matthias Boll
Matthias Boll University of Freiburg
Robert B. Gennis
Robert B. Gennis University of Illinois at Urbana-Champaign
Conrad W. Mullineaux
Conrad W. Mullineaux Queen Mary University of London
Christian Hertweck
Christian Hertweck Friedrich Schiller University Jena
Volker Müller
Volker Müller Goethe University Frankfurt

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