World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
97
Citations
31080
World Ranking
1477
National Ranking
568

Biology and Biochemistry

D-Index
97
Citations
31222
World Ranking
1766
National Ranking
976

Research.com Recognitions

  • 2000 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1988 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1978 - Fellow of Alfred P. Sloan Foundation

Overview

Robert B. Gennis is affiliated with the University of Illinois at Urbana-Champaign in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a specialization in molecular biology as reflected in the majority of their publications. Additional subfields of study include ecology, cell biology, inorganic chemistry, and cellular and molecular neuroscience.

The main topics of Robert B. Gennis's work cover photosynthetic processes and mechanisms, ATP synthase and ATPases research, mitochondrial function and pathology, microbial community ecology and physiology, hemoglobin structure and function, metal-catalyzed oxygenation mechanisms, and biochemical and molecular research.

The scientist has published frequently in several venues, including:

  • Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • ACS Infectious Diseases
  • The FASEB Journal

Some recent significant papers include:

  • "Evolution of the cytochrome bd oxygen reductase superfamily and the function of CydAA' in Archaea" (2021, The ISME Journal)
  • "Role of respiratory NADH oxidation in the regulation of Staphylococcus aureus virulence" (2020, EMBO Reports)
  • "Structures of the intermediates in the catalytic cycle of mitochondrial cytochrome c oxidase" (2022, Biochimica et Biophysica Acta (BBA) - Bioenergetics)
  • "Cryo-EM structures of Escherichia coli cytochrome bo 3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site" (2021, Proceedings of the National Academy of Sciences)
  • "Evolution of quinol oxidation within the heme-copper oxidoreductase superfamily" (2022, Biochimica et Biophysica Acta (BBA) - Bioenergetics)

The frequent co-authors collaborating with Robert B. Gennis include Sangjin Hong, Ranjani Murali, James Hemp, Ziqiao Ding, and Sylvia K. Choi.

Robert B. Gennis has received several fellowships during their career, including recognition as a Fellow of the American Association for the Advancement of Science (AAAS) in 2000, a Fellow of the John Simon Guggenheim Memorial Foundation in 1988, and a Fellow of the Alfred P. Sloan Foundation in 1978.

Best Publications

  • Biomembranes: Molecular Structure and Function

    Robert B. Gennis

  • Energy Transduction by Cytochrome Complexes in Mitochondrial and Bacterial Respiration: The Enzymology of Coupling Electron Transfer Reactions to Transmembrane Proton Translocation

    Bernard L. Trumpower;Robert B. Gennis

  • The superfamily of heme-copper respiratory oxidases.

    J. A. Garcia-Horsman;B. Barquera;J. Rumbley;Jixiang Ma

  • The cytochrome bd respiratory oxygen reductases

    Vitaliy B. Borisov;Robert B. Gennis;James Hemp;Michael I. Verkhovsky

  • Properties of the two terminal oxidases of Escherichia coli.

    Anne Puustinen;Moshe Finel;Tuomas Haltia;Robert B. Gennis

  • The aerobic respiratory chain of Escherichia coli

    Yasuhiro Anraku;Robert B. Gennis

  • The roles of the two proton input channels in cytochrome c oxidase from Rhodobacter sphaeroides probed by the effects of site-directed mutations on time-resolved electrogenic intraprotein proton transfer

    Alexander A. Konstantinov;Sergey Siletsky;David Mitchell;Andrey Kaulen

  • Cytochrome o (cyoABCDE) and d (cydAB) oxidase gene expression in Escherichia coli is regulated by oxygen, pH, and the fnr gene product.

    P A Cotter;V Chepuri;R B Gennis;Robert P Gunsalus

  • The sequence of the cyo operon indicates substantial structural similarities between the cytochrome o ubiquinol oxidase of Escherichia coli and the aa3-type family of cytochrome c oxidases.

    V. Chepuri;L. Lemieux;D. C.-T. Au;R. B. Gennis

  • Cytochrome c oxidase: exciting progress and remaining mysteries.

    Peter Brzezinski;Robert B. Gennis

  • Possible proton relay pathways in cytochrome c oxidase.

    John R. Fetter;Jie Qian;James Shapleigh;Jeffrey W. Thomas

  • Insight into the active-site structure and function of cytochrome oxidase by analysis of site-directed mutants of bacterial cytochrome aa3 and cytochrome bo

    Jonathan P. Hosler;Shelagh Ferguson-Miller;Melissa W. Calhoun;Jeffrey W. Thomas

  • The purification and characterization of the cytochrome d terminal oxidase complex of the Escherichia coli aerobic respiratory chain.

    M. J. Miller;Robert B Gennis

  • The cytochrome oxidase superfamily of redox-driven proton pumps

    Melissa W. Calhoun;Jeffrey W. Thomas;Robert B. Gennis

  • Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

    Kai Li;Lici A. Schurig-Briccio;Xinxin Feng;Ashutosh Upadhyay

  • Structure of the Alternative Complex III in a Supercomplex with Cytochrome Oxidase

    Chang Sun;Samir Benlekbir;Padmaja Venkatakrishnan;Yuhang Wang

  • Multiple proton-conducting pathways in cytochrome oxidase and a proposed role for the active-site tyrosine

    Robert B. Gennis

  • Substitution of asparagine for aspartate-135 in subunit I of the cytochrome bo ubiquinol oxidase of Escherichia coli eliminates proton-pumping activity.

    Jeffrey W. Thomas;Anne Puustinen;James O. Alben;Robert B. Gennis

  • Rapid purification of wildtype and mutant cytochrome c oxidase from Rhodobacter sphaeroides by Ni2+-NTA affinity chromatography

    David M. Mitchell;Robert B. Gennis

  • Energetic efficiency of Escherichia coli: effects of mutations in components of the aerobic respiratory chain.

    M. W. Calhoun;K. L. Oden;R. B. Gennis;M. J.T. De Mattos

Frequent Co-Authors

Peter Brzezinski
Peter Brzezinski Stockholm University
Antony R. Crofts
Antony R. Crofts University of Illinois at Urbana-Champaign
Shelagh Ferguson-Miller
Shelagh Ferguson-Miller Michigan State University
Denis L. Rousseau
Denis L. Rousseau Albert Einstein College of Medicine
Chad M. Rienstra
Chad M. Rienstra University of Illinois at Urbana-Champaign
Gerald T. Babcock
Gerald T. Babcock Michigan State University
Wolfgang Knoll
Wolfgang Knoll Austrian Institute of Technology
Emad Tajkhorshid
Emad Tajkhorshid University of Illinois at Urbana-Champaign
Mårten Wikström
Mårten Wikström University of Helsinki
Hartmut Michel
Hartmut Michel Max Planck Society

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