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Hideto Miyoshi

Hideto Miyoshi

D-Index & Metrics

Chemistry

D-Index
46
Citations
8427
World Ranking
15968
National Ranking
1257

Overview

Hideto Miyoshi is affiliated with Kyoto University in Japan and has an extensive research portfolio primarily in the field of Biochemistry, Genetics, and Molecular Biology. Their work centers heavily on molecular biology with significant contributions also in pharmacology, materials chemistry, biochemistry, and biotechnology.

Their research spans multiple key topics, including:

  • ATP Synthase and ATPases Research
  • Photosynthetic Processes and Mechanisms
  • Mitochondrial Function and Pathology
  • Coenzyme Q10 studies and effects
  • Enzyme Structure and Function
  • Microbial Natural Products and Biosynthesis
  • Traditional and Medicinal Uses of Annonaceae

Notable recent publications by Miyoshi and collaborators include:

  • "Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones," 2020, Nature Communications
  • "IACS-010759, a potent inhibitor of glycolysis-deficient hypoxic tumor cells, inhibits mitochondrial respiratory complex I through a unique mechanism," 2020, Journal of Biological Chemistry
  • "Comprehensive understanding of multiple actions of anticancer drug tamoxifen in isolated mitochondria," 2021, Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • "Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae," 2022, Nature Communications
  • "Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I," 2022, Journal of Biological Chemistry

Frequent co-authors in Miyoshi's body of work include:

  • Masatoshi Murai
  • Takahiro Masuya
  • Moe Ishikawa
  • Blanca Barquera
  • Nicole Butler

Publications by Miyoshi appear repeatedly in several scientific journals, with the most frequent venues being:

  • Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Biochemistry

Best Publications

  • Architecture of succinate dehydrogenase and reactive oxygen species generation.

    Victoria Yankovskaya;Rob Horsefield;Susanna Törnroth;César Luna-Chavez;César Luna-Chavez

  • Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase)

    Hiroko Miyadera;Kazuro Shiomi;Hideaki Ui;Yuichi Yamaguchi

  • Altered Quinone Biosynthesis in the Long-lived clk-1Mutants of Caenorhabditis elegans

    Hiroko Miyadera;Hisako Amino;Akira Hiraishi;Hikari Taka

  • Identification of receptors of main sex-pheromone components of three Lepidopteran species.

    Hidefumi Mitsuno;Takeshi Sakurai;Masatoshi Murai;Tetsuya Yasuda

  • An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria

    Satoshi Ōmura;Hiroko Miyadera;Hideaki Ui;Kazuro Shiomi

  • Accumulation of hydroxycinnamic acid amides induced by pathogen infection and identification of agmatine coumaroyltransferase in Arabidopsis thaliana

    Atsushi Muroi;Atsushi Ishihara;Chihiro Tanaka;Akihiro Ishizuka

  • Structure-activity relationships of some complex I inhibitors.

    Hideto Miyoshi

  • Essential structural factors of annonaceous acetogenins as potent inhibitors of mitochondrial complex I.

    Hideto Miyoshi;Michiyo Ohshima;Hiroko Shimada;Toshio Akagi

  • Uncoupling activity of a newly developed fungicide, fluazinam [3-chloro-N-(3-chloro-2,6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-2-pyridinamine]

    Ze-jian Guo;Hideto Miyoshi;Terumasa Komyoji;Takahiro Haga

  • The ND5 subunit was labeled by a photoaffinity analogue of Fenpyroximate in bovine mitochondrial complex I

    Eiko Nakamaru-Ogiso;Kimitoshi Sakamoto;Akemi Matsuno-Yagi;Hideto Miyoshi

  • Active site rearrangement and structural divergence in prokaryotic respiratory oxidases.

    Schara Safarian;Alexander Hahn;Deryck Mills;Melanie Radloff

  • The biochemical mode of action of the novel selective fungicide cyazofamid: specific inhibition of mitochondrial complex III in Phythium spinosum

    Shigeru Mitani;Satoshi Araki;Yasuko Takii;Takeshi Ohshima

  • Comparison of the inhibitory action of synthetic capsaicin analogues with various NADH-ubiquinone oxidoreductases.

    Takashi Satoh;Hideto Miyoshi;Kimitoshi Sakamoto;Hajime Iwamura

  • Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones

    Kento Tsukada;Shono Shinki;Akiho Kaneko;Kazuma Murakami

  • Anaerobic NADH-Fumarate Reductase System Is Predominant in the Respiratory Chain of Echinococcus multilocularis, Providing a Novel Target for the Chemotherapy of Alveolar Echinococcosis

    Jun Matsumoto;Kimitoshi Sakamoto;Noriko Shinjyo;Yasutoshi Kido

  • Identification of a novel quinone-binding site in the cytochrome bo complex from Escherichia coli.

    M Sato-Watanabe;T Mogi;T Ogura;T Kitagawa

  • Characterization of the membrane domain subunit NuoJ (ND6) of the NADH-quinone oxidoreductase from Escherichia coli by chromosomal DNA manipulation.

    Kao Mc;Di Bernardo S;Nakamaru-Ogiso E;Miyoshi H

  • Molecular mechanisms for the induction of peroxidase activity of the cytochrome c-cardiolipin complex.

    Masato Abe;Ryota Niibayashi;Shinya Koubori;Ikuko Moriyama

  • Quantitative relationship between protonophoric and uncoupling activities of substituted phenols.

    Hideto Miyoshi;Takaaki Nishioka;Toshio Fujita

  • IACS-010759, a potent inhibitor of glycolysis-deficient hypoxic tumor cells, inhibits mitochondrial respiratory complex I through a unique mechanism

    Atsuhito Tsuji;Takumi Akao;Takahiro Masuya;Masatoshi Murai

  • Stabilization of a semiquinone radical at the high-affinity quinone-binding site (QH) of the Escherichia coli bo-type ubiquinol oxidase

    Mariko Sato-Watanabe;Sigeru Itoh;Tatsushi Mogi;Katsumi Matsuura

  • Comparison of the inhibitory action of natural rotenone and its stereoisomers with various NADH-ubiquinone reductases.

    Hideki Ueno;Hideto Miyoshi;Kenkichi Ebisui;Hajime Iwamura

Frequent Co-Authors

Takaaki Nishioka
Takaaki Nishioka Kyoto University
Kiyoshi Kita
Kiyoshi Kita Nagasaki University
Toshio Fujita
Toshio Fujita Kyoto University
Kazuro Shiomi
Kazuro Shiomi Kitasato University
Takao Yagi
Takao Yagi Scripps Research Institute
Yasuo Shinohara
Yasuo Shinohara University of Tokushima
Satoshi Omura
Satoshi Omura Kitasato University
Kazunobu Matsushita
Kazunobu Matsushita Yamaguchi University
Osao Adachi
Osao Adachi Yamaguchi University
Gary Cecchini
Gary Cecchini University of California, San Francisco

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