What is he best known for?
The fields of study he is best known for:
His main research concerns Mitochondrion, Caenorhabditis elegans, Mutant, Mutation and Genetics.
Siegfried Hekimi combines subjects such as Oxidative stress, Superoxide dismutase and Reactive oxygen species with his study of Mitochondrion.
His studies link Longevity with Caenorhabditis elegans.
His work in Mutant tackles topics such as Allele which are related to areas like Wild type, Period, Gene mutation, Daf-16 and Disorders of sex development.
His work is dedicated to discovering how Mutation, Phenotype are connected with CLOCK, Gene interaction and Genetics of aging and other disciplines.
In general Genetics, his work in Gene, Genetic recombination, Mitotic crossover and Ectopic recombination is often linked to Gene density linking many areas of study.
His most cited work include:
- The genetics of caloric restriction in Caenorhabditis elegans (768 citations)
- Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. (495 citations)
- Determination of life-span in Caenorhabditis elegans by four clock genes. (469 citations)
What are the main themes of his work throughout his whole career to date?
Siegfried Hekimi spends much of his time researching Caenorhabditis elegans, Genetics, Mutant, Cell biology and Mitochondrion.
Within one scientific family, he focuses on topics pertaining to Mutation under Caenorhabditis elegans, and may sometimes address concerns connected to Cell cycle and Genetics of aging.
His work carried out in the field of Mutant brings together such families of science as Caenorhabditis and RNA interference.
His Cell biology research incorporates themes from Electron transport chain and Gene expression, Transcriptional regulation.
His study in Mitochondrion is interdisciplinary in nature, drawing from both Oxidative stress, Superoxide dismutase and Reactive oxygen species.
His Oxidative stress study integrates concerns from other disciplines, such as Genetic model and Immunology.
He most often published in these fields:
- Caenorhabditis elegans (50.40%)
- Genetics (41.60%)
- Mutant (37.60%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (30.40%)
- Mitochondrion (29.60%)
- Caenorhabditis elegans (50.40%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, Mitochondrion, Caenorhabditis elegans, Reactive oxygen species and Mitochondrial ROS.
His Cell biology research is multidisciplinary, relying on both Cell and Gene expression.
His Mitochondrion study incorporates themes from Endocrinology, Mutant, Internal medicine and Longevity.
As part of one scientific family, Siegfried Hekimi deals mainly with the area of Mutant, narrowing it down to issues related to the Oxidative stress, and often Mitochondrial respiratory chain.
His research on Caenorhabditis elegans concerns the broader Genetics.
Siegfried Hekimi works mostly in the field of Reactive oxygen species, limiting it down to topics relating to Superoxide and, in certain cases, Superoxide dismutase.
Between 2013 and 2021, his most popular works were:
- Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling. (290 citations)
- The Intrinsic Apoptosis Pathway Mediates the Pro-Longevity Response to Mitochondrial ROS in C. elegans (235 citations)
- Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging (158 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Mitochondrion, Cell biology, Reactive oxygen species, Signal transduction and Biochemistry.
He has included themes like Coenzyme Q10, Premature ovarian failure and Internal medicine in his Mitochondrion study.
His Cell biology course of study focuses on Superoxide and Electron transport chain and Antioxidant.
His work carried out in the field of Signal transduction brings together such families of science as Superoxide dismutase and Mutant.
Siegfried Hekimi has included themes like Oxidative stress, Apoptosis and Gene expression in his Mutant study.
His Paraquat research integrates issues from Cell signaling, Caenorhabditis elegans, Dose–response relationship, Vitamin C and Metabolism.
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