World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
17870
World Ranking
14176
National Ranking
5978

Overview

Gordon J. Lithgow is affiliated with the Buck Institute for Research on Aging in the United States. The research focus centers largely on the biology of aging and longevity, with an emphasis on molecular and biochemical pathways that influence lifespan and healthspan.

Their research publications span multiple disciplines, primarily within biochemistry, genetics, molecular biology, and medicine. Subfields frequently addressed include aging, molecular biology, physiology, endocrine and autonomic systems, and cell biology.

Key topics in Gordon J. Lithgow's work are genetics, aging, and longevity in model organisms, mitochondrial function and pathology, circadian rhythm and melatonin, adipose tissue and metabolism, the effects of spaceflight on biology, frailty in older adults, and aging and gerontology research.

Frequently published venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PubMed
  • GeroScience
  • eLife
  • Innovation in Aging

Their recent notable papers include:

  • Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice (2020, Cell Metabolism)
  • Taurine deficiency as a driver of aging (2023, Science)
  • Moving geroscience from the bench to clinical care and health policy (2021, Journal of the American Geriatrics Society)
  • The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging (2021, eLife)
  • Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction (2020, Nature Communications)

Frequent co-authors in their publications include:

  • Manish Chamoli
  • Anna Foulger
  • Julie K. Andersen
  • Patrick C. Phillips
  • Monica Driscoll

Best Publications

  • Geroscience: Linking Aging to Chronic Disease

    Brian K. Kennedy;Shelley L. Berger;Anne Brunet;Judith Campisi;Judith Campisi

  • Extension of life-span with superoxide dismutase/catalase mimetics

    Simon Melov;Joanne Ravenscroft;Sarwatt Malik;Matt S. Gill

  • Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress.

    Gordon J. Lithgow;Tiffany M. White;Simon Melov;Thomas E. Johnson

  • From discoveries in ageing research to therapeutics for healthy ageing

    Judith Campisi;Pankaj Kapahi;Gordon J. Lithgow;Simon Melov

  • Long live FOXO: unraveling the role of FOXO proteins in aging and longevity

    Rute Martins;Gordon J. Lithgow;Wolfgang Link

  • Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans.

    Kally Z. Pan;Julia E. Palter;Aric N. Rogers;Anders Olsen

  • MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8.

    Dipa Bhaumik;Gary K. Scott;Shiruyeh Schokrpur;Christopher K. Patil

  • Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan

    Silvestre Alavez;Maithili C. Vantipalli;David J. S. Zucker;David J. S. Zucker;Ida M. Klang;Ida M. Klang

  • Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin‐like signals

    Glenda A. Walker;Gordon J. Lithgow;Gordon J. Lithgow

  • Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans

    Dalia Barsyte;David A. Lovejoy;Gordon J. Lithgow

  • Identification of a novel cis-regulatory element involved in the heat shock response in Caenorhabditis elegans using microarray gene expression and computational methods.

    Debraj GuhaThakurta;Lisanne Palomar;Gary D. Stormo;Pat Tedesco

  • Thermotolerance of a long-lived mutant of Caenorhabditis elegans.

    Gordon J. Lithgow;Tiffany M. White;Douglas A. Hinerfeld;Thomas E. Johnson

  • Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice.

    Azar Asadi Shahmirzadi;Azar Asadi Shahmirzadi;Daniel Edgar;Chen-Yu Liao;Yueh-Mei Hsu

  • Evolution of lifespan in C. elegans

    David W. Walker;Gawain McColl;Nicole L. Jenkins;Jennifer Harris

  • Mortality rates in a genetically heterogeneous population of Caenorhabditis elegans

    Anne Brooks;Gordon J. Lithgow;Thomas E. Johnson

  • Pharmacogenetic Analysis of Lithium-induced Delayed Aging in Caenorhabditis elegans*

    Gawain McColl;David W. Killilea;Alan E. Hubbard;Maithili C. Vantipalli

  • Stress Biology and Aging Mechanisms: Toward Understanding the Deep Connection Between Adaptation to Stress and Longevity

    Elissa S. Epel;Gordon J. Lithgow

  • Fitness cost of extended lifespan in Caenorhabditis elegans

    Nicole L. Jenkins;Gawain McColl;Gordon J. Lithgow

  • Hypothesis: Interventions That Increase the Response to Stress Offer the Potential for Effective Life Prolongation and Increased Health

    Thomas E. Johnson;Gordon J. Lithgow;Shin Murakami

  • Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice

    Azar Asadi Shahmirzadi;Azar Asadi Shahmirzadi;Daniel Edgar;Chen-Yu Liao;Yueh-Mei Hsu

Frequent Co-Authors

Julie K. Andersen
Julie K. Andersen Buck Institute for Research on Aging
Patrick C. Phillips
Patrick C. Phillips University of Oregon
Monica Driscoll
Monica Driscoll Rutgers, The State University of New Jersey
Pankaj Kapahi
Pankaj Kapahi Buck Institute for Research on Aging
Simon Melov
Simon Melov Buck Institute for Research on Aging
Thomas E. Johnson
Thomas E. Johnson University of Colorado Boulder
Bradford W. Gibson
Bradford W. Gibson Buck Institute for Research on Aging
Brian K. Kennedy
Brian K. Kennedy National University of Singapore
Birgit Schilling
Birgit Schilling Buck Institute for Research on Aging
Judith Campisi
Judith Campisi Buck Institute for Research on Aging

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

A background in biology and biochemistry opens a range of academic and professional options across the health sciences. Many students start by pursuing an asn online degree, which provides foundational skills for nursing and healthcare support roles.

Nutrition and wellness careers are also popular choices. The best online registered dietitian programs are designed for those interested in food science, clinical nutrition, or helping others maintain healthy lifestyles.

For those seeking leadership in healthcare management, reviewing the number of cahme accredited mha programs is essential. Accreditation ensures that graduates qualify for advanced administrative and executive positions in hospitals and health organizations.

Students aiming for the highest level of clinical practice can consider online dnp programs without clinicals. These targeted doctorates are ideal for those who wish to advance their careers while balancing work or family commitments.

Best Scientists Citing Gordon J. Lithgow

Trending Scientists

Recently Published Articles