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Biology and Biochemistry

D-Index
60
Citations
15621
World Ranking
11809
National Ranking
5080

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1993 - Fellow of Alfred P. Sloan Foundation

Overview

Monica Driscoll is affiliated with Rutgers, The State University of New Jersey in the United States. The primary fields of study for Driscoll's research include Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields such as Aging, Molecular Biology, Physiology, Endocrine and Autonomic Systems, and Cell Biology.

Driscoll's research focuses on topics related to Genetics, Aging, and Longevity in Model Organisms. Other significant areas of study include the effects of spaceflight on biology, circadian rhythm and melatonin, mitochondrial function and pathology, endoplasmic reticulum stress and disease, adipose tissue and metabolism, and autophagy in disease and therapy.

Frequent publication venues for Driscoll include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • PubMed
  • Innovation in Aging
  • Journal of Visualized Experiments

Driscoll has collaborated extensively with several coauthors, including:

  • Christine A. Sedore
  • Gordon J. Lithgow
  • Patrick C. Phillips
  • Anna L Coleman-Hulbert
  • Brian Onken

Selected recent papers by Monica Driscoll include:

  • "NemaLife chip: a micropillar-based microfluidic culture device optimized for aging studies in crawling C. elegans," 2020, Scientific Reports
  • "Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling," 2021, Proceedings of the National Academy of Sciences
  • "Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes," 2021, Aging Cell
  • "Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons," 2024, Nature Aging
  • "Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell," 2023, eLife

Monica Driscoll is a recipient of notable awards including Fellow of the American Association for the Advancement of Science (AAAS) awarded in 2012 and Fellow of the Alfred P. Sloan Foundation in 1993.

Best Publications

  • Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans.

    Laura A. Herndon;Peter J. Schmeissner;Justyna M. Dudaronek;Paula A. Brown

  • A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

    Malene Bredahl Hansen;Abha Chandra;Laura L. Mitic;Brian Onken

  • The mec -4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration

    Monica Driscoll;Martin Chalfie

  • Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

    Brian Onken;Monica Driscoll

  • Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes.

    Nektarios Tavernarakis;Shi Liang Wang;Maxim Dorovkov;Alexey Ryazanov

  • Mechanosensory signalling in C. elegans mediated by the GLR-1 glutamate receptor

    Andres V. Maricq;Erin Peckol;Monica Driscoll;Cornelia I. Bargmann

  • Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans

    Popi Syntichaki;Keli Xu;Monica Driscoll;Nektarios Tavernarakis

  • C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress

    Ilija Melentijevic;Marton L. Toth;Meghan L. Arnold;Ryan J. Guasp

  • In Vivo Imaging of C. elegans Mechanosensory Neurons Demonstrates a Specific Role for the MEC-4 Channel in the Process of Gentle Touch Sensation

    Hiroshi Suzuki;Rex Kerr;Laura Bianchi;Christian Frøkjær-Jensen;Christian Frøkjær-Jensen

  • In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans

    Beate Gerstbrein;Georgios Stamatas;Nikiforos Kollias;Monica Driscoll

  • Necrotic Cell Death in C. elegans Requires the Function of Calreticulin and Regulators of Ca2+ Release from the Endoplasmic Reticulum

    Keli Xu;Nektarios Tavernarakis;Monica Driscoll

  • Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors.

    Marios Chatzigeorgiou;Sungjae Yoo;Joseph D. Watson;Wei Hsiang Lee

  • MOLECULAR MODELING OF MECHANOTRANSDUCTION IN THE NEMATODE CAENORHABDITIS ELEGANS

    Nektarios Tavernarakis;Monica Driscoll

  • Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity.

    Monica Driscoll;E. Dean;E. Reilly;E. Bergholz

  • The SPFH domain: implicated in regulating targeted protein turnover in stomatins and other membrane-associated proteins

    Nektarios Tavernarakis;Monica Driscoll;Nikos C. Kyrpides

  • A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans

    Kyonsoo Hong;Monica Driscoll

  • unc-8, a DEG/ENaC Family Member, Encodes a Subunit of a Candidate Mechanically Gated Channel That Modulates C. elegans Locomotion

    Nektarios Tavernarakis;Wayne Shreffler;Shiliang Wang;Monica Driscoll

  • A novel mitotimer reporter gene for mitochondrial content, structure, stress, and damage in vivo

    Rhianna C. Laker;Peng Xu;Karen A. Ryall;Alyson Sujkowski

  • Modulated microRNA expression during adult lifespan in Caenorhabditis elegans.

    Carolina Ibáñez-Ventoso;Maocheng Yang;Suzhen Guo;Harlan Robins

  • Neurite Sprouting and Synapse Deterioration in the Aging Caenorhabditis elegans Nervous System

    Marton Lorant Toth;Ilija Melentijevic;Leena Shah;Aatish Bhatia

Frequent Co-Authors

Nektarios Tavernarakis
Nektarios Tavernarakis Foundation for Research and Technology Hellas
Gordon J. Lithgow
Gordon J. Lithgow Buck Institute for Research on Aging
Patrick C. Phillips
Patrick C. Phillips University of Oregon
William R Schafer
William R Schafer MRC Laboratory of Molecular Biology
Martin Chalfie
Martin Chalfie Columbia University
David H. Hall
David H. Hall Albert Einstein College of Medicine
Adam Antebi
Adam Antebi Max Planck Society
Joel N. Meyer
Joel N. Meyer Duke University
Ding Xue
Ding Xue University of Colorado Boulder
Oliver Hobert
Oliver Hobert Columbia University

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