Richard Vandlen

Overview

Best Publications

• Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

  Jagath R Junutula;Helga Raab;Suzanna Clark;Sunil Bhakta

  1433
  Citations

• Characterization of a multicomponent receptor for GDNF

  James J. S. Treanor;Laurie Goodman;Frederic de Sauvage;Donna M. Stone

  1344
  Citations

• Identification of heregulin, a specific activator of p185erbB2.

  William E. Holmes;Mark X. Sliwkowski;Robert W. Akita;William J. Henzel

  1340
  Citations

• Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

  Ben-Quan Shen;Keyang Xu;Luna Liu;Helga Raab

  1025
  Citations

• The Carboxyl-terminal Domain(111–165) of Vascular Endothelial Growth Factor Is Critical for Its Mitogenic Potency

  Bruce A. Keyt;Lea T. Berleau;Hung V. Nguyen;Helen Chen

  961
  Citations

• Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin.

  M.X. Sliwkowski;G. Schaefer;R.W. Akita;J.A. Lofgren

  894
  Citations

• Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

  Sophie M. Lehar;Thomas Pillow;Min Xu;Leanna Staben

  772
  Citations

• Cysteine engineered antibodies and conjugates

  Charles W. Eigenbrot;Jagath Reddy Junutula;Henry Lowman;Helga E. Raab

  728
  Citations

• Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.

  Ling Fu;Linu M. John;Sean H. Adams;Xing Xian Yu

  666
  Citations

• Persephin, a Novel Neurotrophic Factor Related to GDNF and Neurturin

  Jeffrey Milbrandt;Frederic J de Sauvage;Timothy J Fahrner;Robert H Baloh

  642
  Citations

• Spatial control of EGF receptor activation by reversible dimerization on living cells

  Inhee Chung;Robert Akita;Richard Vandlen;Derek Toomre

  594
  Citations

• IL-17E, a Novel Proinflammatory Ligand for the IL-17 Receptor Homolog IL-17Rh1

  James Lee;Wei-Hsien Ho;Miko Maruoka;Racquel T. Corpuz

  591
  Citations

• Decreased food intake does not completely account for adiposity reduction after ob protein infusion.

  N Levin;C Nelson;A Gurney;R Vandlen

  560
  Citations

• A GPI-linked Protein That Interacts With Ret to Form a Candidate Neurturin Receptor

  Robert D. Klein;Robert D. Klein;Daniel Sherman;Wei-Hsien Ho;Donna Stone

  501
  Citations

• The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

  Hilary F. Clark;Austin L. Gurney;Evangeline Abaya;Kevin Baker

  478
  Citations

• Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer.

  Jagath R. Junutula;Kelly M. Flagella;Richard A. Graham;Kathryn L. Parsons

  318
  Citations

• Antibody-Drug Conjugates for the Treatment of Non–Hodgkin's Lymphoma: Target and Linker-Drug Selection

  Andrew G. Polson;Jill Calemine-Fenaux;Pamela Chan;Wesley Chang

  295
  Citations

• High-Level Expression and Characterization of a Purified 142-Residue Polypeptide of the Prion Protein†

  I Mehlhorn;D Groth;J Stöckel;B Moffat

  292
  Citations

• Antibodies against the gH/gL/UL128/UL130/UL131 Complex Comprise the Majority of the Anti-Cytomegalovirus (Anti-CMV) Neutralizing Antibody Response in CMV Hyperimmune Globulin

  Ashley E. Fouts;Pamela Chan;Jean-Philippe Stephan;Richard Vandlen

  280
  Citations

• IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp.

  Guohua Pan;Phillip Risser;Weiguang Mao;Daryl T. Baldwin

  279
  Citations