What is he best known for?
The fields of study he is best known for:
Richard Vandlen mainly focuses on Biochemistry, Molecular biology, Cell biology, Conjugate and In vivo.
Richard Vandlen interconnects Cell culture, Tyrosine kinase, Receptor, Transmembrane protein and IL 17 family in the investigation of issues within Molecular biology.
His Cell biology research is multidisciplinary, relying on both Neurotrophic factors, Artemin, Glial cell line-derived neurotrophic factor, Neurturin and GDNF family of ligands.
Conjugate overlaps with fields such as Antibody, Pharmacology and Protein engineering in his research.
His Antibody research incorporates elements of Amino acid, Cysteine, Sequence and Peptide.
His research in In vivo intersects with topics in Antigen and Drug.
His most cited work include:
- Characterization of a multicomponent receptor for GDNF (1000 citations)
- Identification of heregulin, a specific activator of p185erbB2. (994 citations)
- Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index (916 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Biochemistry, Antibody, Molecular biology, Receptor and Neuregulin.
In the field of Biochemistry, his study on Nucleic acid, Amino acid, Peptide and Antibiotics overlaps with subjects such as Ob Protein.
Richard Vandlen combines subjects such as Antigen and In vivo with his study of Antibody.
His Molecular biology research integrates issues from Proinflammatory cytokine, Tyrosine kinase, Epidermal growth factor and Transmembrane protein.
His Receptor study incorporates themes from Cytokine, Somatostatin and Cell biology.
His Cell biology research is multidisciplinary, incorporating perspectives in Neurotrophic factors, Artemin, Glial cell line-derived neurotrophic factor, Neurturin and GDNF family of ligands.
He most often published in these fields:
- Biochemistry (41.67%)
- Antibody (39.17%)
- Molecular biology (26.67%)
What were the highlights of his more recent work (between 2013-2021)?
- Antibody (39.17%)
- Conjugate (15.83%)
- Biochemistry (41.67%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Antibody, Conjugate, Biochemistry, Linker and Molecular biology.
His work on Monoclonal as part of general Antibody research is often related to Brentuximab vedotin, thus linking different fields of science.
The Antibiotics research he does as part of his general Biochemistry study is frequently linked to other disciplines of science, such as Selective Estrogen Receptor Down Regulator, therefore creating a link between diverse domains of science.
His Molecular biology research incorporates themes from Virology, Epitope, Antigen, Internalization and Computational biology.
His studies in Antigen integrate themes in fields like Extracellular, Epidermal growth factor, EGFL7 and Biotinylation.
The In vivo study combines topics in areas such as Antibody-drug conjugate and Metabolism.
Between 2013 and 2021, his most popular works were:
- Novel antibody–antibiotic conjugate eliminates intracellular S. aureus (362 citations)
- Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates (87 citations)
- Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering. (74 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Conjugate, Drug, In vivo, Antibody and Pathogen.
His Conjugate study spans across into fields like Small molecule, Stereochemistry, Antibody-drug conjugate, Payload and Homogeneous.
His Drug study is concerned with the field of Pharmacology as a whole.
His In vivo study combines topics in areas such as In vitro, Therapeutic index, Amide, Targeted drug delivery and Combinatorial chemistry.
His work carried out in the field of Antibody brings together such families of science as Cysteine and Protein aggregation.
His Pathogen study which covers Intracellular that intersects with Antibiotics.
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