What is he best known for?
The fields of study he is best known for:
- Enzyme
- Antibody
- Amino acid
His primary scientific interests are in Biochemistry, Antibody, Immunology, In vivo and Molecular biology.
In general Biochemistry study, his work on Peptide, Phage display and Serum albumin often relates to the realm of Conjugate, thereby connecting several areas of interest.
His Antibody research includes elements of Peptide library, Pharmacology and Antigen.
His study in Immunology is interdisciplinary in nature, drawing from both Transferrin receptor, Receptor and Blood–brain barrier.
His study looks at the relationship between In vivo and topics such as Antibody-drug conjugate, which overlap with Lymphoma and Chronic lymphocytic leukemia.
His biological study deals with issues like Semaphorin, which deal with fields such as Blocking antibody.
His most cited work include:
- Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index (916 citations)
- Albumin Binding as a General Strategy for Improving the Pharmacokinetics of Proteins (654 citations)
- Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target (488 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Antibody, Biochemistry, Immunology, Molecular biology and Cancer research.
As part of one scientific family, he deals mainly with the area of Antibody, narrowing it down to issues related to the Apoptosis, and often Nucleic acid.
His study in Biochemistry focuses on Kallikrein, Peptide, Serine protease, Amino acid and Plasmin.
His research on Immunology focuses in particular on Immune system.
His research in Molecular biology intersects with topics in Transferrin receptor and Receptor.
In his study, Antibody-drug conjugate is strongly linked to In vivo, which falls under the umbrella field of Cancer research.
He most often published in these fields:
- Antibody (48.44%)
- Biochemistry (28.65%)
- Immunology (18.75%)
What were the highlights of his more recent work (between 2017-2020)?
- Antibody (48.44%)
- Biochemistry (28.65%)
- Transferrin receptor (7.81%)
In recent papers he was focusing on the following fields of study:
Mark S. Dennis mainly investigates Antibody, Biochemistry, Transferrin receptor, Cell biology and Blood–brain barrier.
His work in the fields of Antibody, such as Immunoconjugate, intersects with other areas such as Linker.
His Biochemistry study integrates concerns from other disciplines, such as Avidity and CD79B.
His studies deal with areas such as Penetrant, Knockout mouse and In vivo as well as Cell biology.
His In vivo study incorporates themes from Cytokine, Toxicity and Therapeutic index.
Mark S. Dennis works mostly in the field of Central nervous system, limiting it down to topics relating to Enzyme and, in certain cases, Pharmacology.
Between 2017 and 2020, his most popular works were:
- Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation (55 citations)
- Relative Target Affinities of T Cell-Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model (42 citations)
- Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys. (32 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Antibody
- Amino acid
Mark S. Dennis spends much of his time researching Antibody, T cell, Transferrin receptor, Blood–brain barrier and In vivo.
He is studying Monoclonal, which is a component of Antibody.
The T cell study combines topics in areas such as Cytokine, Toxicity, Therapeutic index and Immunotherapy.
His work deals with themes such as Neuroinflammation, Central nervous system, Microglia and Cell biology, which intersect with Transferrin receptor.
The various areas that Mark S. Dennis examines in his Blood–brain barrier study include Cell, Transferrin, Binding site and Immunoglobulin G.
His In vivo study frequently draws connections to adjacent fields such as Pharmacology.
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