Daniel Kirchhofer

Overview

Best Publications

• Albumin Binding as a General Strategy for Improving the Pharmacokinetics of Proteins

  Mark S. Dennis;Min Zhang;Y. Gloria Meng;Miryam Kadkhodayan

  1148
  Citations

• The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.

  David W. Banner;Allan D'Arcy;Christiana Chène;Fritz K. Winkler

  1058
  Citations

• Alpha 2 beta 1 integrins from different cell types show different binding specificities.

  D Kirchhofer;L R Languino;E Ruoslahti;M D Pierschbacher

  375
  Citations

• Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury.

  Patricia Redecha;Rachel Tilley;Michael Tencati;Jane E. Salmon

  350
  Citations

• Inflammasome activation triggers blood clotting and host death through pyroptosis

  Congqing Wu;Wei Lu;Yan Zhang;Guoying Zhang

  314
  Citations

• Crystal structure of the HGF β‐chain in complex with the Sema domain of the Met receptor

  Jennifer Stamos;Robert A Lazarus;Xiaoyi Yao;Daniel Kirchhofer

  303
  Citations

• Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.

  Daniel Kirchhofer;Mark Peek;Michael T. Lipari;Karen Billeci

  250
  Citations

• Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer.

  Jian Guo Wang;Julia E. Geddings;Maria M. Aleman;Jessica C. Cardenas

  218
  Citations

• Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor

  Yingnan Zhang;Charles Eigenbrot;Lijuan Zhou;Steven Shia

  205
  Citations

• anticorpo anti-pcsk9 ou um fragmento de anticorpo que se liga a pcsk9, ácido nucleico isolado, vetor, célula hospedeira, método para fabricar um anticorpo anti-pcsk9, composição farmacêutica, método de redução do nível de colesterol ldl em um sujeito e método de tratamento de hipercolesterolemia em um sujeito

  Peterson Andrew;Chiu Cecilia;Kirchhofer Daniel;Kolumam Ganesh

  197
  Citations

• Monocyte tissue factor–dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin

  A. Phillip Owens;Freda H. Passam;Silvio Antoniak;Stephanie M. Marshall

  196
  Citations

• Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets

  Jessica R. Hitchcock;Charlotte N. Cook;Saeeda Bobat;Ewan A. Ross

  180
  Citations

• Local protease signaling contributes to neural tube closure in the mouse embryo.

  Eric Camerer;Eric Camerer;Adrian Barker;Daniel N. Duong;Rajkumar Ganesan

  180
  Citations

• Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1.

  Daniel Kirchhofer;Mark Peek;Wei Li;Jennifer Stamos

  168
  Citations

• Specific Accumulation of Circulating Monocytes and Polymorphonuclear Leukocytes on Platelet Thrombi in a Vascular Injury Model

  Daniel Kirchhofer;Markus A. Riederer;Hans R. Baumgartner

  163
  Citations

• Levels of microparticle tissue factor activity correlate with coagulation activation in endotoxemic mice

  J. G. Wang;D. Manly;D. Kirchhofer;R. Pawlinski

  157
  Citations

• PAR-1 contributes to the innate immune response during viral infection

  Silvio Antoniak;A. Phillip Owens;Martin Baunacke;Julie C. Williams

  156
  Citations

• Cation-dependent changes in the binding specificity of the platelet receptor GPIIb/IIIa.

  D Kirchhofer;J Gailit;E Ruoslahti;J Grzesiak

  153
  Citations

• Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.

  Michael T. Lipari;Wei Li;Paul Moran;Monica Kong-Beltran

  152
  Citations

• Structural and Functional Basis of the Serine Protease-like Hepatocyte Growth Factor β-Chain in Met Binding and Signaling

  Daniel Kirchhofer;Xiaoyi Yao;Mark Peek;Charles Eigenbrot

  139
  Citations