World's Best Scientists 2026 revealed!
Daniel Kirchhofer

Daniel Kirchhofer

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
11712
World Ranking
10960
National Ranking
4743

Daniel Kirchhofer publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Daniel Kirchhofer sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 174 publications — 38th percentile

38% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Daniel Kirchhofer D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Daniel Kirchhofer sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 62 D-Index — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Daniel Kirchhofer is affiliated with Genentech in the United States and has contributed to research across various fields related to medicine, biochemistry, genetics, and molecular biology. Their work spans numerous subfields including molecular biology, immunology, neurology, radiology, nuclear medicine and imaging, and epidemiology.

Their research topics frequently address issues in cerebrovascular and genetic disorders, inflammasome and immune disorders, monoclonal and polyclonal antibodies research, neutrophil, myeloperoxidase and oxidative mechanisms, lipoproteins and cardiovascular health, glaucoma and retinal disorders, and phagocytosis and immune regulation.

Kirchhofer's recent scholarly papers include:

  • Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis, 2021, Cardiovascular Research
  • Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy, 2020, Proceedings of the National Academy of Sciences
  • Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge, 2020, Nature Communications
  • Domain-Specific Antibodies Reveal Differences in the Membrane Topologies of Apolipoprotein L1 in Serum and Podocytes, 2020, Journal of the American Society of Nephrology
  • Design of Organo-Peptides As Bipartite PCSK9 Antagonists, 2020, ACS Chemical Biology

Frequent co-authors in Kirchhofer's work are:

  • Mark Ultsch
  • Charles Eigenbrot
  • Stefan Gerhardy
  • Yan Zhang
  • Congqing Wu

Kirchhofer's publications are commonly featured in several venues including:

  • UNC Libraries
  • Nature Communications
  • Communications Biology
  • Cardiovascular Research
  • Proceedings of the National Academy of Sciences

The body of work by Daniel Kirchhofer integrates interdisciplinary approaches spanning molecular biology and medicine, emphasizing antibody research and mechanisms of immune regulation. Their contributions encompass both basic science and therapeutic development, illustrating a broad engagement with biomedical research focused on molecular and cellular processes underlying human diseases.

Best Publications

  • Albumin Binding as a General Strategy for Improving the Pharmacokinetics of Proteins

    Mark S. Dennis;Min Zhang;Y. Gloria Meng;Miryam Kadkhodayan

  • The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.

    David W. Banner;Allan D'Arcy;Christiana Chène;Fritz K. Winkler

  • Alpha 2 beta 1 integrins from different cell types show different binding specificities.

    D Kirchhofer;L R Languino;E Ruoslahti;M D Pierschbacher

  • Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury.

    Patricia Redecha;Rachel Tilley;Michael Tencati;Jane E. Salmon

  • Inflammasome activation triggers blood clotting and host death through pyroptosis

    Congqing Wu;Wei Lu;Yan Zhang;Guoying Zhang

  • Crystal structure of the HGF β‐chain in complex with the Sema domain of the Met receptor

    Jennifer Stamos;Robert A Lazarus;Xiaoyi Yao;Daniel Kirchhofer

  • Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.

    Daniel Kirchhofer;Mark Peek;Michael T. Lipari;Karen Billeci

  • Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer.

    Jian Guo Wang;Julia E. Geddings;Maria M. Aleman;Jessica C. Cardenas

  • Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor

    Yingnan Zhang;Charles Eigenbrot;Lijuan Zhou;Steven Shia

  • anticorpo anti-pcsk9 ou um fragmento de anticorpo que se liga a pcsk9, ácido nucleico isolado, vetor, célula hospedeira, método para fabricar um anticorpo anti-pcsk9, composição farmacêutica, método de redução do nível de colesterol ldl em um sujeito e método de tratamento de hipercolesterolemia em um sujeito

    Peterson Andrew;Chiu Cecilia;Kirchhofer Daniel;Kolumam Ganesh

  • Monocyte tissue factor–dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin

    A. Phillip Owens;Freda H. Passam;Silvio Antoniak;Stephanie M. Marshall

  • Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets

    Jessica R. Hitchcock;Charlotte N. Cook;Saeeda Bobat;Ewan A. Ross

  • Local protease signaling contributes to neural tube closure in the mouse embryo.

    Eric Camerer;Eric Camerer;Adrian Barker;Daniel N. Duong;Rajkumar Ganesan

  • Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1.

    Daniel Kirchhofer;Mark Peek;Wei Li;Jennifer Stamos

  • Specific Accumulation of Circulating Monocytes and Polymorphonuclear Leukocytes on Platelet Thrombi in a Vascular Injury Model

    Daniel Kirchhofer;Markus A. Riederer;Hans R. Baumgartner

  • Levels of microparticle tissue factor activity correlate with coagulation activation in endotoxemic mice

    J. G. Wang;D. Manly;D. Kirchhofer;R. Pawlinski

  • PAR-1 contributes to the innate immune response during viral infection

    Silvio Antoniak;A. Phillip Owens;Martin Baunacke;Julie C. Williams

  • Cation-dependent changes in the binding specificity of the platelet receptor GPIIb/IIIa.

    D Kirchhofer;J Gailit;E Ruoslahti;J Grzesiak

  • Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.

    Michael T. Lipari;Wei Li;Paul Moran;Monica Kong-Beltran

  • Structural and Functional Basis of the Serine Protease-like Hepatocyte Growth Factor β-Chain in Met Binding and Signaling

    Daniel Kirchhofer;Xiaoyi Yao;Mark Peek;Charles Eigenbrot

Frequent Co-Authors

Nigel Mackman
Nigel Mackman University of North Carolina at Chapel Hill
Christian Wiesmann
Christian Wiesmann Novartis (Switzerland)
Menno van Lookeren Campagne
Menno van Lookeren Campagne Amgen (United States)
Dan L. Eaton
Dan L. Eaton Genentech
Mark Ultsch
Mark Ultsch Genentech

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