What is he best known for?
The fields of study he is best known for:
His main research concerns Cell biology, Matriptase, Transmembrane protein, Proteases and ST14.
The study incorporates disciplines such as Stroma, Matrix metalloproteinase, Metalloproteinase and Plasmin in addition to Cell biology.
His Matriptase study typically links adjacent topics like Molecular biology.
He has researched Transmembrane protein in several fields, including Serine protease, Membrane protein, Stratum corneum and Serine.
Proteases is a primary field of his research addressed under Biochemistry.
His research in ST14 intersects with topics in Tight junction and Hair follicle.
His most cited work include:
- Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein (476 citations)
- Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes (322 citations)
- Type II transmembrane serine proteases. (319 citations)
What are the main themes of his work throughout his whole career to date?
Thomas H. Bugge spends much of his time researching Cell biology, Molecular biology, Matriptase, Proteases and Biochemistry.
His studies deal with areas such as Collagen receptor, Plasmin and Proteolysis as well as Cell biology.
The various areas that he examines in his Molecular biology study include Urokinase receptor, Matrix metalloproteinase and Anthrax toxin.
The Matriptase study which covers Zymogen that intersects with PRSS8.
His Proteases research is multidisciplinary, incorporating elements of Serine, Protease, Proteolytic enzymes, Gene and Hepatocyte Growth Factor Activator.
His Serine protease study deals with Transmembrane protein intersecting with Hepsin.
He most often published in these fields:
- Cell biology (36.02%)
- Molecular biology (23.66%)
- Matriptase (23.12%)
What were the highlights of his more recent work (between 2014-2021)?
- Cell biology (36.02%)
- Anthrax toxin (11.83%)
- Molecular biology (23.66%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Anthrax toxin, Molecular biology, Cancer research and Matriptase.
His studies in Cell biology integrate themes in fields like Endocytic cycle and Collagen receptor.
His Molecular biology study incorporates themes from Viability assay, Cell culture, Apoptosis, MTT assay and Plasminogen activator.
His biological study spans a wide range of topics, including Carcinogenesis, Cell, Metastasis and Immunology.
His Matriptase research is classified as research in Serine protease.
His Serine protease study combines topics in areas such as Epithelium, Serine and Blot.
Between 2014 and 2021, his most popular works were:
- Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. (78 citations)
- Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake (53 citations)
- Non-hematopoietic PAR-2 is essential for matriptase-driven pre-malignant progression and potentiation of ras-mediated squamous cell carcinogenesis. (40 citations)
In his most recent research, the most cited papers focused on:
Thomas H. Bugge focuses on Cell biology, Matriptase, Proteases, Molecular biology and Serine protease.
Thomas H. Bugge studies Signal transduction, a branch of Cell biology.
His research integrates issues of Carcinogenesis, Cell and Cancer research in his study of Matriptase.
Thomas H. Bugge has included themes like Idiopathic pulmonary fibrosis, Pulmonary fibrosis, Western blot and Blot in his Molecular biology study.
His Serine protease study integrates concerns from other disciplines, such as Lung and Serine.
His PRSS8 research incorporates elements of Internal medicine, Hair follicle and ST14.
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