His main research concerns Cell biology, Matriptase, Transmembrane protein, Proteases and ST14. The study incorporates disciplines such as Stroma, Matrix metalloproteinase, Metalloproteinase and Plasmin in addition to Cell biology. His Matriptase study typically links adjacent topics like Molecular biology.
He has researched Transmembrane protein in several fields, including Serine protease, Membrane protein, Stratum corneum and Serine. Proteases is a primary field of his research addressed under Biochemistry. His research in ST14 intersects with topics in Tight junction and Hair follicle.
Thomas H. Bugge spends much of his time researching Cell biology, Molecular biology, Matriptase, Proteases and Biochemistry. His studies deal with areas such as Collagen receptor, Plasmin and Proteolysis as well as Cell biology. The various areas that he examines in his Molecular biology study include Urokinase receptor, Matrix metalloproteinase and Anthrax toxin.
The Matriptase study which covers Zymogen that intersects with PRSS8. His Proteases research is multidisciplinary, incorporating elements of Serine, Protease, Proteolytic enzymes, Gene and Hepatocyte Growth Factor Activator. His Serine protease study deals with Transmembrane protein intersecting with Hepsin.
His primary areas of study are Cell biology, Anthrax toxin, Molecular biology, Cancer research and Matriptase. His studies in Cell biology integrate themes in fields like Endocytic cycle and Collagen receptor. His Molecular biology study incorporates themes from Viability assay, Cell culture, Apoptosis, MTT assay and Plasminogen activator.
His biological study spans a wide range of topics, including Carcinogenesis, Cell, Metastasis and Immunology. His Matriptase research is classified as research in Serine protease. His Serine protease study combines topics in areas such as Epithelium, Serine and Blot.
Thomas H. Bugge focuses on Cell biology, Matriptase, Proteases, Molecular biology and Serine protease. Thomas H. Bugge studies Signal transduction, a branch of Cell biology. His research integrates issues of Carcinogenesis, Cell and Cancer research in his study of Matriptase.
Thomas H. Bugge has included themes like Idiopathic pulmonary fibrosis, Pulmonary fibrosis, Western blot and Blot in his Molecular biology study. His Serine protease study integrates concerns from other disciplines, such as Lung and Serine. His PRSS8 research incorporates elements of Internal medicine, Hair follicle and ST14.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein
Manuel Yepes;Maria Sandkvist;Elizabeth G. Moore;Thomas H. Bugge.
Journal of Clinical Investigation (2003)
Type II transmembrane serine proteases.
Thomas H. Bugge;Toni M. Antalis;Qingyu Wu.
Journal of Biological Chemistry (2009)
Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes
Silvia Montaner;Akrit Sodhi;Akrit Sodhi;Alfredo Molinolo;Thomas H Bugge.
Cancer Cell (2003)
Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis.
Karin List;Karin List;Christian C Haudenschild;Roman Szabo;WanJun Chen.
Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer.
Sarah Netzel-Arnett;John D Hooper;Roman Szabo;Edwin L Madison.
Cancer and Metastasis Reviews (2003)
Prothrombin deficiency results in embryonic and neonatal lethality in mice
William Y. Sun;David P. Witte;Jay L. Degen;Melissa C. Colbert.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation
Karin List;Roman Szabo;Alfredo Molinolo;Virote Sriuranpong.
Genes & Development (2005)
Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1
Karin List;Karin List;Roman Szabo;Philip W. Wertz;Julie Segre.
Journal of Cell Biology (2003)
Proteolytic Activation of the 1918 Influenza Virus Hemagglutinin
Chawaree Chaipan;Darwyn Kobasa;Darwyn Kobasa;Stephanie Bertram;Ilona Glowacka.
Journal of Virology (2009)
Type II transmembrane serine proteases.
Roman Szabo;Qingyu Wu;Robert B. Dickson;Sarah Netzel-Arnett.
Thrombosis and Haemostasis (2003)
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