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Biology and Biochemistry

D-Index
67
Citations
14668
World Ranking
8284
National Ranking
3745

Overview

Arthur E. Frankel is affiliated with Wake Forest University in the United States. Their research focuses primarily within the field of Medicine, with significant contributions in subfields such as Oncology, Epidemiology, Infectious Diseases, Genetics, and Molecular Biology.

Frankel's recent publications cover a range of topics in clinical and biomedical research including COVID-19, cancer therapies, and immunology. Notable papers include:

  • Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib, 2021, Clinical Case Reports
  • North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: position on standards of care and areas of need, 2022, Blood
  • A Phase I/Ib Trial of PD 0332991 (Palbociclib) and T-DM1 in HER2-Positive Advanced Breast Cancer After Trastuzumab and Taxane Therapy, 2021, Clinical Breast Cancer
  • Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis, 2022, Angiogenesis
  • Unbiased Microbiome and Metabolomic Profiling of Fecal Samples from Patients with Melanoma, 2021, Methods in molecular biology

The frequent publication venues for their work include:

  • Clinical Case Reports
  • Blood
  • Clinical Breast Cancer
  • Angiogenesis
  • Methods in molecular biology

Frankel has collaborated multiple times with colleagues such as Chul Ahn, Eknath Naik, Hans Carl Hasselbalch, Tazio Capozzola, and Raiees Andrabi.

Their research interests are concentrated in several core topics, including:

  • SARS-CoV-2 and COVID-19 Research
  • Cutaneous lymphoproliferative disorders research
  • Fungal Infections and Studies
  • CAR-T cell therapy research
  • Advanced Breast Cancer Therapies
  • HER2/EGFR in Cancer Research
  • Chronic Lymphocytic Leukemia Research

The research profile of Arthur E. Frankel illustrates an interdisciplinary approach to medicine, addressing infectious diseases like COVID-19, cancer biology, and immunotherapy. Their work spans a range of clinical and molecular topics, contributing to ongoing developments in patient care standards and therapeutic strategies.

Best Publications

  • A STING-activating nanovaccine for cancer immunotherapy

    Min Luo;Hua Wang;Zhaohui Wang;Haocheng Cai

  • Pivotal Phase III Trial of Two Dose Levels of Denileukin Diftitox for the Treatment of Cutaneous T-Cell Lymphoma

    Elise Olsen;Madeleine Duvic;Arthur Frankel;Youn Kim

  • Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients

    Arthur E. Frankel;Laura A. Coughlin;Jiwoong Kim;Thomas W. Froehlich

  • Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients.

    Y Xu;D C Gaudette;J D Boynton;A Frankel

  • CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies

    Ugo Testa;Elvira Pelosi;Arthur Frankel

  • Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

    Jacqueline Thorburn;Henrick Horita;Jasmina Redzic;Kirk Hansen

  • Characterization of diphtheria fusion proteins targeted to the human interleukin-3 receptor.

    Arthur E. Frankel;Jason Ramage;Melanie Kiser;Richard Alexander

  • Evaluation of monoclonal antibodies for the development of breast cancer immunotoxins

    Michael J. Bjorn;David Ring;Arthur Frankel

  • Phase I Trial of a Novel Diphtheria Toxin/Granulocyte Macrophage Colony-stimulating Factor Fusion Protein (DT388GMCSF) for Refractory or Relapsed Acute Myeloid Leukemia

    Arthur E. Frankel;Bayard L. Powell;Philip D. Hall;L. Douglas Case

  • Phase I evaluation of an anti-breast carcinoma monoclonal antibody 260F9-recombinant ricin A chain immunoconjugate.

    L. M. Weiner;J. O'Dwyer;J. Kitson;R. L. Comis

  • A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.

    Michaela Feuring-Buske;Arthur E. Frankel;Richard L. Alexander;Brigitte Gerhard

  • Nature and distribution of feline sarcoma virus nucleotide sequences.

    Arthur E Frankel;J. H. Gilbert;K. J. Porzig;E. M. Scolnick

  • Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias.

    Arthur E Frankel;J. A. McCubrey;M. S. Miller;S. Delatte

  • Immunotoxins: a clinical review of their use in the treatment of malignancies.

    Andrew A. Hertler;Arthur E. Frankel

  • Clinical evaluation of intraperitoneal Pseudomonas exotoxin immunoconjugate OVB3-PE in patients with ovarian cancer.

    L H Pai;M A Bookman;R F Ozols;R C Young

  • Phase I Study of an Anti-Breast Cancer Immunotoxin by Continuous Infusion: Report of a Targeted Toxic Effect Not Predicted by Animal Studies

    Bruce J. Gould;Michael J. Borowitz;Eric S. Groves;Peter W. Carter

  • Phase I trial of H65-RTA immunoconjugate in patients with cutaneous T- cell lymphoma

    C. F. LeMaistre;S. Rosen;Arthur E Frankel;S. Kornfeld

  • Role of arginine 180 and glutamic acid 177 of ricin toxin A chain in enzymatic inactivation of ribosomes.

    Arthur Frankel;Phil Welsh;Jane Richardson;Jon D. Robertus

  • Tissue distribution of breast cancer-associated antigens defined by monoclonal antibodies.

    Arthur E Frankel;D. B. Ring;F. Tringale;S. T. Hsieh-Ma

  • Immunotoxin therapy of cancer.

    A. E. Frankel

Frequent Co-Authors

Mark C. Willingham
Mark C. Willingham Wake Forest University
Stephen H. Leppla
Stephen H. Leppla National Institutes of Health
Andrew Thorburn
Andrew Thorburn University of Colorado Denver
Bayard L. Powell
Bayard L. Powell Wake Forest University
Thomas H. Bugge
Thomas H. Bugge National Institutes of Health
Daniel A. Vallera
Daniel A. Vallera University of Minnesota
Robert J. Kreitman
Robert J. Kreitman National Cancer Institute
Michael R. Zalutsky
Michael R. Zalutsky Duke University
Robert C. Bast
Robert C. Bast The University of Texas MD Anderson Cancer Center
Michael J. Borowitz
Michael J. Borowitz Johns Hopkins University

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