What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Cell biology, Molecular biology, Receptor, Biochemistry and Endocytosis.
His Cell biology research is multidisciplinary, incorporating perspectives in Cell, Membrane and Cell membrane.
His study in Molecular biology is interdisciplinary in nature, drawing from both P-glycoprotein, Virus, Cytotoxic T cell, Pseudomonas exotoxin and Antibody.
Mark C. Willingham interconnects Immunohistochemistry and Pathology in the investigation of issues within Antibody.
His Biochemistry research focuses on Biophysics and how it relates to Endocytic vesicle, Concanavalin A and Coated vesicle.
His research in Endocytosis intersects with topics in alpha-2-Macroglobulin, Transferrin and Vesicle.
His most cited work include:
- Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues (2446 citations)
- Expression of Multidrug Resistance Gene in Human Cancers (1142 citations)
- The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection (975 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Molecular biology, Cell biology, Cancer research, Biochemistry and Internal medicine.
Mark C. Willingham has researched Molecular biology in several fields, including Cell culture, Recombinant DNA and Immunofluorescence, Antibody, Monoclonal antibody.
His Antibody study combines topics from a wide range of disciplines, such as Immunohistochemistry, Pathology and Antigen.
Mark C. Willingham interconnects Receptor, Cell and Endocytosis in the investigation of issues within Cell biology.
His study in Cancer research is interdisciplinary in nature, drawing from both Carcinogenesis, Cancer, Thyroid hormone receptor, Apoptosis and Immunology.
He works mostly in the field of Internal medicine, limiting it down to concerns involving Endocrinology and, occasionally, Cell growth.
He most often published in these fields:
- Molecular biology (33.58%)
- Cell biology (21.41%)
- Cancer research (19.95%)
What were the highlights of his more recent work (between 2005-2020)?
- Cancer research (19.95%)
- Internal medicine (16.30%)
- Endocrinology (14.11%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cancer research, Internal medicine, Endocrinology, Thyroid hormone receptor and Thyroid cancer.
Mark C. Willingham has researched Cancer research in several fields, including Carcinogenesis, Cancer cell, Apoptosis, Receptor and PTEN.
The concepts of his Receptor study are interwoven with issues in Coactivator and Cell biology.
His work carried out in the field of Internal medicine brings together such families of science as Gastroenterology, Mesothelioma and Oncology.
His research investigates the connection between Thyroid hormone receptor and topics such as Thyroid hormone receptor beta that intersect with problems in Hormone.
His work deals with themes such as Cell, Prostate, Molecular biology, Antibody and Prostate cancer, which intersect with Immunohistochemistry.
Between 2005 and 2020, his most popular works were:
- Phase I Study of SS1P, a Recombinant Anti-Mesothelin Immunotoxin Given as a Bolus I.V. Infusion to Patients with Mesothelin-Expressing Mesothelioma, Ovarian, and Pancreatic Cancers (303 citations)
- Hepatic Niemann-Pick C1–like 1 regulates biliary cholesterol concentration and is a target of ezetimibe (284 citations)
- Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages (277 citations)
In his most recent research, the most cited papers focused on:
Mark C. Willingham mostly deals with Internal medicine, Cancer research, Endocrinology, Thyroid cancer and Thyroid hormone receptor beta.
His Internal medicine research includes themes of Gastroenterology and Genetically modified mouse.
His Cancer research study incorporates themes from Carcinogenesis, Immune system, Immunology, Cytotoxic T cell and Lung cancer.
His research integrates issues of Phospholipid and Fatty liver in his study of Endocrinology.
His Thyroid hormone receptor beta study combines topics in areas such as Thyroid hormone receptor and Thyroid.
His biological study spans a wide range of topics, including T cell, Transfection and Cell biology.
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