World's Best Scientists 2026 revealed!
Darell D. Bigner

Darell D. Bigner

D-Index & Metrics

Medicine

D-Index
159
Citations
142407
World Ranking
798
National Ranking
451

Darell D. Bigner publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Darell D. Bigner sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 958 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Darell D. Bigner D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Darell D. Bigner sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 159 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Darell D. Bigner is affiliated with Duke University in the United States. Their research activity spans multiple fields, including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these broader areas, Darell's work features subfields such as Immunology, Oncology, Molecular Biology, Genetics, and Cancer Research.

The main topics covered in Darell's research portfolio include:

  • CAR-T cell therapy research
  • Glioma Diagnosis and Treatment
  • Immunotherapy and Immune Responses
  • Cancer Research and Treatments
  • Virus-based gene therapy research
  • Interferon and immune responses
  • Immune cells in cancer

Darell has published extensively in scientific journals, with a number of recent papers demonstrating their research focus and collaborative work. Notable papers include:

  • Pan-cancer analysis of whole genomes, 2020, published in Nature
  • Divergent mutational processes distinguish hypoxic and normoxic tumours, 2020, Nature Communications
  • Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy, 2021, Nature Communications
  • Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma, 2021, Journal for ImmunoTherapy of Cancer
  • Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition, 2022, Cancer Cell

The scientist frequently publishes in several venues, highlighting their active engagement in specific research communities. These venues include:

  • Neuro-Oncology
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal for ImmunoTherapy of Cancer
  • UNC Libraries

Darell collaborates regularly with a number of coauthors, reflecting a network of academic partnerships. Frequent coauthors include:

  • David M. Ashley
  • Matthias Gromeier
  • Annick Desjardins
  • Michael C. Brown
  • James E. Herndon

The breadth of Darell D. Bigner's research contributions combines clinical and molecular insights, particularly in cancer, immunology, and gene therapy areas. Their work involves both experimental and translational approaches aimed at understanding tumors, immune response mechanisms, and therapeutic strategies.

Best Publications

  • Mutations of the BRAF gene in human cancer

    Helen Davies;Graham R. Bignell;Charles Cox;Philip Stephens

  • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

    Shideng Bao;Qiulian Wu;Roger E McLendon;Yueling Hao

  • An Integrated Genomic Analysis of Human Glioblastoma Multiforme

    D. Williams Parsons;Siân Jones;Xiaosong Zhang;Jimmy Cheng-Ho Lin

  • IDH1 and IDH2 Mutations in Gliomas

    Hai Yan;D. Williams Parsons;Genglin Jin;Roger McLendon

  • The Somatic Genomic Landscape of Glioblastoma

    Cameron W. Brennan;Roel G W Verhaak;Aaron McKenna;Benito Campos

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Bevacizumab Plus Irinotecan in Recurrent Glioblastoma Multiforme

    James J. Vredenburgh;Annick Desjardins;James E. Herndon;Jennifer Marcello

  • Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

    Shideng Bao;Qiulian Wu;Sith Sathornsumetee;Yueling Hao

  • TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

    Patrick J. Killela;Zachary J. Reitman;Yuchen Jiao;Chetan Bettegowda

  • Phase II Trial of Bevacizumab and Irinotecan in Recurrent Malignant Glioma

    James J. Vredenburgh;Annick Desjardins;James E. Herndon;Jeannette M. Dowell

  • Altered Telomeres in Tumors with ATRX and DAXX Mutations

    Christopher M. Heaphy;Roeland F. de Wilde;Yuchen Jiao;Alison P. Klein

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.

    Albert J. Wong;Sandra H. Bigner;Darell D. Bigner;Kenneth W. Kinzler

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL

    Hai Yan;P.J. Killela;Z.J. Reitman;Y. Jiao

  • The somatic genomic landscape of glioblastoma

    Cameron W. Brennan;Roel G. W. Verhaak;Aaron Mckenna;Benito Campos

Frequent Co-Authors

Henry S. Friedman
Henry S. Friedman Duke University
Roger E. McLendon
Roger E. McLendon Duke University
John H. Sampson
John H. Sampson Duke University
Allan H. Friedman
Allan H. Friedman Duke University
James E. Herndon
James E. Herndon Duke University
Michael R. Zalutsky
Michael R. Zalutsky Duke University
Gary E. Archer
Gary E. Archer Duke University
David A. Reardon
David A. Reardon Harvard University
Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh
Bert Vogelstein
Bert Vogelstein Johns Hopkins University

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