World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
60
Citations
13100
World Ranking
3122
National Ranking
1236

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Antibiotics
  • Tuberculosis

His scientific interests lie mostly in Tuberculosis, Mycobacterium tuberculosis, Isoniazid, Pharmacology and Pyrazinamide. His Tuberculosis study integrates concerns from other disciplines, such as Regimen, Internal medicine, Single-strand conformation polymorphism and Immunology. Jacques H. Grosset interconnects In vitro, Antibiotics, Microbiology, Virology and Virulence in the investigation of issues within Mycobacterium tuberculosis.

His Isoniazid study combines topics from a wide range of disciplines, such as Gastroenterology and Multiple drug resistance. His Pharmacology research integrates issues from Rifapentine, Pharmacotherapy and Rifamycin. The study incorporates disciplines such as Moxifloxacin, Chemotherapy and SQ109 in addition to Pyrazinamide.

His most cited work include:

  • Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis (485 citations)
  • Fluoroquinolones, tuberculosis, and resistance (321 citations)
  • A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: Application to Mycobacterium tuberculosis (314 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Tuberculosis, Pharmacology, Mycobacterium tuberculosis, Microbiology and Antibacterial agent. His studies deal with areas such as Regimen, Internal medicine, Immunology and Clofazimine as well as Tuberculosis. His research in Pharmacology intersects with topics in Moxifloxacin and Rifapentine.

His Mycobacterium tuberculosis research incorporates themes from In vitro, Mutant, Gene, Lung and Granuloma. The Microbiology study combines topics in areas such as Guinea pig, Virology, In vivo and Ratón. His Antibacterial agent research includes themes of Clarithromycin and Rifampicin.

He most often published in these fields:

  • Tuberculosis (50.33%)
  • Pharmacology (36.42%)
  • Mycobacterium tuberculosis (30.46%)

What were the highlights of his more recent work (between 2011-2019)?

  • Tuberculosis (50.33%)
  • Pharmacology (36.42%)
  • Clofazimine (15.23%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Tuberculosis, Pharmacology, Clofazimine, Rifapentine and Regimen. Jacques H. Grosset is interested in Mycobacterium tuberculosis, which is a field of Tuberculosis. His Pharmacology research is multidisciplinary, incorporating perspectives in Pyrazinamide, Ethambutol, Isoniazid and Bedaquiline.

His Ethambutol research includes elements of Culture conversion, Moxifloxacin and Clarithromycin. As a part of the same scientific family, Jacques H. Grosset mostly works in the field of Clofazimine, focusing on Dosing and, on occasion, Combination therapy and Guinea pig. His Rifapentine study incorporates themes from Rifamycin and TB chemotherapy.

Between 2011 and 2019, his most popular works were:

  • Targeting DnaN for tuberculosis therapy using novel griselimycins (168 citations)
  • Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis (104 citations)
  • New drugs for the treatment of tuberculosis: hope and reality. (96 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Bacteria
  • Antibiotics

His primary areas of investigation include Tuberculosis, Pharmacology, Clofazimine, Ethambutol and Mycobacterium tuberculosis. His research integrates issues of Gastroenterology and Regimen in his study of Tuberculosis. Regimen is closely attributed to Pyrazinamide in his study.

His Mycobacterium tuberculosis study combines topics in areas such as Complementation, Mutant, Efflux and Mutation. His work focuses on many connections between Culture conversion and other disciplines, such as Moxifloxacin, that overlap with his field of interest in Surgery. The various areas that Jacques H. Grosset examines in his Rifapentine study include Rifamycin and SQ109.

Best Publications

  • Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis

    Vadim Makarov;Giulia Manina;Katarina Mikusova;Ute Möllmann

  • Fluoroquinolones, tuberculosis, and resistance

    Amy Sarah Ginsburg;Jacques H Grosset;William R Bishai

  • Nosocomial bronchopneumonia in the critically ill. Histologic and bacteriologic aspects.

    J J Rouby;E Martin De Lassale;P Poete;M H Nicolas

  • A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: Application to Mycobacterium tuberculosis

    Gyanu Lamichhane;Matteo Zignol;Natalie J. Blades;Deborah E. Geiman

  • Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: A molecular study

    B. Heym;N. Honoré;C. Schurra;S.T. Cole

  • Targeting DnaN for tuberculosis therapy using novel griselimycins

    Angela Kling;Peer Lukat;Deepak V. Almeida;Armin Bauer

  • Efficacy of the combination rifampin-streptomycin in preventing growth of Mycobacterium ulcerans in early lesions of Buruli ulcer in humans

    S. Etuaful;B. Carbonnelle;J. Grosset;S. Lucas

  • Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates from KwaZulu-Natal

    Keira A. Cohen;Thomas Abeel;Abigail Manson McGuire;Christopher A. Desjardins

  • Dormancy Phenotype Displayed by Extracellular Mycobacterium tuberculosis within Artificial Granulomas in Mice

    Petros C. Karakousis;Tetsuyuki Yoshimatsu;Gyanu Lamichhane;Samuel C. Woolwine

  • Mycobacterium tuberculosis in the Extracellular Compartment: an Underestimated Adversary

    Jacques Grosset

  • Bactericidal Activity of the Nitroimidazopyran PA-824 in a Murine Model of Tuberculosis

    Sandeep Tyagi;E. Nuermberger;T. Yoshimatsu;K. Williams

  • Promising Clinical Efficacy of Streptomycin-Rifampin Combination for Treatment of Buruli Ulcer (Mycobacterium ulcerans Disease)

    Annick Chauty;Marie Françoise Ardant;Ambroise Adeye;Hélène Euverte

  • Moxifloxacin-containing Regimens of Reduced Duration Produce a Stable Cure in Murine Tuberculosis

    Eric L. Nuermberger;Tetsuyuki Yoshimatsu;Sandeep Tyagi;Kathy Williams

  • In Vitro and In Vivo Activities of Moxifloxacin and Clinafloxacin against Mycobacterium tuberculosis

    Baohong Ji;Nacer Lounis;Caroline Maslo;Chantal Truffot-Pernot

  • Promising Antituberculosis Activity of the Oxazolidinone PNU-100480 Relative to That of Linezolid in a Murine Model

    K. N. Williams;C. K. Stover;T. Zhu;R. Tasneen

  • Powerful Bactericidal and Sterilizing Activity of a Regimen Containing PA-824, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis

    Eric Nuermberger;Sandeep Tyagi;Rokeya Tasneen;Kathy N. Williams

  • Mutations in pepQ Confer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis

    Deepak Almeida;Thomas Ioerger;Sandeep Tyagi;Si Yang Li

  • Antagonism between isoniazid and the combination pyrazinamide-rifampin against tuberculosis infection in mice.

    J Grosset;C Truffot-Pernot;C Lacroix;B Ji

  • Role of the dosR-dosS Two-Component Regulatory System in Mycobacterium tuberculosis Virulence in Three Animal Models†

    Paul J. Converse;Petros C. Karakousis;Lee G. Klinkenberg;Anup K. Kesavan

  • Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance

    Christopher A. Desjardins;Keira A. Cohen;Keira A. Cohen;Vanisha. Munsamy;Thomas. Abeel;Thomas. Abeel

  • Iron and Mycobacterium tuberculosis infection

    Nacer Lounis;Chantal Truffot-Pernot;Jacques Grosset;Victor R. Gordeuk

  • Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis

    Ian M. Rosenthal;Rokeya Tasneen;Charles A. Peloquin;Ming Zhang

Frequent Co-Authors

Eric L. Nuermberger
Eric L. Nuermberger Johns Hopkins University
Petros C. Karakousis
Petros C. Karakousis Johns Hopkins University
William R. Bishai
William R. Bishai Johns Hopkins University
Vincent Jarlier
Vincent Jarlier Sorbonne University
Stewart T. Cole
Stewart T. Cole Institut Pasteur
Richard E. Chaisson
Richard E. Chaisson Johns Hopkins University
Mario Raviglione
Mario Raviglione University of Milan
David N. McMurray
David N. McMurray Texas A&M University
Emmanuelle Cambau
Emmanuelle Cambau Université Paris Cité
John W. Adamson
John W. Adamson University of California, San Diego

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