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Medicine

D-Index
126
Citations
66824
World Ranking
2928
National Ranking
1624

Overview

David A. Reardon is affiliated with Harvard University in the United States. The primary fields of study in their research include Medicine and Biochemistry, Genetics and Molecular Biology. Their work extensively covers subfields such as Genetics, Oncology, Pulmonary and Respiratory Medicine, Immunology, and Molecular Biology.

The main research topics addressed by David A. Reardon are:

  • Glioma Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Radiomics and Machine Learning in Medical Imaging
  • Brain Metastases and Treatment
  • Immunotherapy and Immune Responses
  • Cancer Research and Treatments

Key recent papers authored or co-authored by David A. Reardon include:

  • Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma, 2020, JAMA Oncology
  • Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions, 2020, Neuro-Oncology
  • Mechanisms and therapeutic implications of hypermutation in gliomas, 2020, Nature
  • Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter, 2022, Neuro-Oncology
  • Radiotherapy combined with nivolumab or temozolomide for newly diagnosed glioblastoma with unmethylated MGMT promoter: An international randomized phase III trial, 2022, Neuro-Oncology

The scientist frequently collaborates with the following colleagues:

  • Patrick Y. Wen
  • Eudocia Q. Lee
  • Keith L. Ligon
  • Wenya Linda Bi
  • Ugonma Chukwueke

David A. Reardon's research has been published mainly in the following venues:

  • Neuro-Oncology
  • Journal of Clinical Oncology
  • Neuro-Oncology Advances
  • Clinical Cancer Research
  • ONCOLOGY

Their work is noted for its involvement in oncology with a strong focus on glioma and glioblastoma treatments, integrating immunotherapy approaches and exploring biomarkers. The research contributions also extend to the development of therapeutic strategies involving CAR-T cell therapy and radiomics applied in medical imaging.

Best Publications

  • IDH1 and IDH2 Mutations in Gliomas

    Hai Yan;D. Williams Parsons;Genglin Jin;Roger McLendon

  • Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group

    Patrick Y. Wen;David R. Macdonald;David A. Reardon;Timothy F. Cloughesy

  • Bevacizumab Plus Irinotecan in Recurrent Glioblastoma Multiforme

    James J. Vredenburgh;Annick Desjardins;James E. Herndon;Jennifer Marcello

  • Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

    Derin B. Keskin;Annabelle J. Anandappa;Jing Sun;Itay Tirosh

  • Phase II Trial of Bevacizumab and Irinotecan in Recurrent Malignant Glioma

    James J. Vredenburgh;Annick Desjardins;James E. Herndon;Jeannette M. Dowell

  • Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain.

    Hussein A. Tawbi;Peter A. Forsyth;Alain Algazi;Omid Hamid

  • Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma.

    Timothy F. Cloughesy;Aaron Y. Mochizuki;Joey R. Orpilla;Willy Hugo

  • Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

    Roger Stupp;Roger Stupp;Monika E Hegi;Thierry Gorlia;Sara C Erridge

  • Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: The CheckMate 143 Phase 3 Randomized Clinical Trial

    David A. Reardon;Alba A. Brandes;Antonio Omuro;Paul Mulholland

  • Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma

    John H. Sampson;Amy B Heimberger;Gary E. Archer;Kenneth D. Aldape

  • Phase II Trial of Gefitinib in Recurrent Glioblastoma

    Jeremy N. Rich;David A. Reardon;Terry Peery;Jeannette M. Dowell

  • Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions

    Patrick Y. Wen;Michael Weller;Eudocia Quant Lee;Brian M. Alexander

  • Immunotherapy response assessment in neuro-oncology: a report of the RANO working group.

    Hideho Okada;Michael Weller;Raymond Huang;Gaetano Finocchiaro

  • Mechanisms and therapeutic implications of hypermutation in gliomas.

    Mehdi Touat;Mehdi Touat;Mehdi Touat;Yvonne Y. Li;Yvonne Y. Li;Adam N. Boynton;Adam N. Boynton;Liam F. Spurr;Liam F. Spurr

  • Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas

    M. J. van den Bent;J. S. Wefel;D. Schiff;M. J. B. Taphoorn

  • Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients

    Duane A. Mitchell;Kristen A. Batich;Michael D. Gunn;Min-Nung Huang

  • Randomized Phase II Study of Cilengitide, an Integrin-Targeting Arginine-Glycine-Aspartic Acid Peptide, in Recurrent Glioblastoma Multiforme

    David A. Reardon;Karen L. Fink;Tom Mikkelsen;Timothy F. Cloughesy

  • Molecular targeted therapy of glioblastoma

    Emilie Le Rhun;Matthias Preusser;Patrick Roth;David A. Reardon

  • Nivolumab with or without ipilimumab in patients with recurrent glioblastoma: results from exploratory phase I cohorts of CheckMate 143

    Antonio Omuro;Gordana Vlahovic;Michael Lim;Solmaz Sahebjam

  • Clinical Experience with α-Particle–Emitting 211At: Treatment of Recurrent Brain Tumor Patients with 211At-Labeled Chimeric Antitenascin Monoclonal Antibody 81C6

    Michael R. Zalutsky;David A. Reardon;Gamal Akabani;R. Edward Coleman

Frequent Co-Authors

Patrick Y. Wen
Patrick Y. Wen Harvard University
James J. Vredenburgh
James J. Vredenburgh Yale School of Medicine
Henry S. Friedman
Henry S. Friedman Duke University
Keith L. Ligon
Keith L. Ligon Harvard University
John H. Sampson
John H. Sampson Duke University
James E. Herndon
James E. Herndon Duke University
Allan H. Friedman
Allan H. Friedman Duke University
Darell D. Bigner
Darell D. Bigner Duke University
Timothy F. Cloughesy
Timothy F. Cloughesy University of California, Los Angeles
Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh

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