D-Index & Metrics Best Publications

Bert Vogelstein

Johns Hopkins University
United States

Genetics

USA

2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Best Scientists D-index 281 Citations 456,371 792 World Ranking 15 National Ranking 13

Medicine D-index 267 Citations 385,367 757 World Ranking 12 National Ranking 10

Genetics D-index 263 Citations 413,583 711 World Ranking 2 National Ranking 2

Research.com Recognitions

Awards & Achievements

2023 - Research.com Medicine in United States Leader Award

2023 - Research.com Genetics in United States Leader Award

2022 - Research.com Best Scientist Award

2022 - Research.com Genetics and Molecular Biology in United States Leader Award

2021 - Japan Prize for their pioneering work in conceptualizing a multi-step model of carcinogenesis and its application and impact on improving cancer diagnosis and therapy.

2020 - Jessie Stevenson Kovalenko Medal, US National Academy of Sciences For his pioneering work in elucidating the fundamental principles of the molecular basis of human cancer and the application of this knowledge to improve the clinical management of patients.

2019 - Albany Medical Center Prize in Medicine and Biomedical Research

2019 - Gruber Prize in Genetics

2015 - Fellow, National Academy of Inventors

2015 - Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson for his breakthroughs in oncology research.

2013 - Breakthrough Prize in Life Sciences for cancer genomics and tumor suppressor genes.

2007 - Robert J. and Claire Pasarow Foundation Medical Research Award

2006 - Fellow of the American Association for the Advancement of Science (AAAS)

2001 - Member of the National Academy of Medicine (NAM)

2000 - Charles S. Mott Prize, General Motors Cancer Research Foundation

1998 - Paul Ehrlich and Ludwig Darmstaedter Prize

1998 - William Allan Award, the American Society of Human Genetics

1998 - Louisa Gross Horwitz Prize, Columbia University

1997 - William Beaumont Prize, American Gastroenterological Association (AGA)

1992 - Fellow of the American Academy of Arts and Sciences

1992 - Member of the National Academy of Sciences

1992 - Canada Gairdner International Award

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

Gene
Cancer
DNA

Genetics, Cancer research, Gene, Mutation and Carcinogenesis are his primary areas of study. His Genetics study frequently links to other fields, such as Cell biology. The concepts of his Cancer research study are interwoven with issues in Immunology, Point mutation, Tumor suppressor gene and Colorectal cancer, Adenomatous polyposis coli.

Gene and Molecular biology are frequently intertwined in his study. His Mutation research includes elements of Phenotype, Malignancy and Cell growth. His Carcinogenesis study combines topics from a wide range of disciplines, such as Tumor progression, KRAS and Carcinoma.

His most cited work include:

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity (21819 citations)
A genetic model for colorectal tumorigenesis (9589 citations)
WAF1, a potential mediator of p53 tumor suppression (7441 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Gene, Cancer research, Genetics, Molecular biology and Cancer. Gene is frequently linked to DNA in his study. While the research belongs to areas of Cancer research, Bert Vogelstein spends his time largely on the problem of Colorectal cancer, intersecting his research to questions surrounding Oncology.

His Genetics and Mutation, Allele, DNA mismatch repair, Genome and Chromosome investigations all form part of his Genetics research activities. His study looks at the intersection of Molecular biology and topics like Cell biology with Cell cycle. His study in Cancer focuses on Pancreatic cancer in particular.

He most often published in these fields:

Gene (34.62%)
Cancer research (34.51%)
Genetics (32.80%)

What were the highlights of his more recent work (between 2013-2021)?

Cancer (20.36%)
Cancer research (34.51%)
Internal medicine (12.54%)

In recent papers he was focusing on the following fields of study:

Bert Vogelstein spends much of his time researching Cancer, Cancer research, Internal medicine, Pathology and Oncology. The various areas that he examines in his Cancer study include Aneuploidy, Computational biology and Stem cell. The Cancer research study combines topics in areas such as Gene, Somatic cell, Blockade, Gene mutation and KRAS.

His Gene study is associated with Genetics. His Pathology research integrates issues from Biomarker, Carcinogenesis and Bladder cancer. His work in the fields of Oncology, such as Adjuvant, intersects with other areas such as In patient.

Between 2013 and 2021, his most popular works were:

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency (4640 citations)
Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies (2454 citations)
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade (2396 citations)

In his most recent research, the most cited papers focused on:

Gene
Cancer
DNA

Bert Vogelstein mostly deals with Cancer research, Cancer, Internal medicine, Mutation and Pathology. His Cancer research study incorporates themes from Gene expression profiling, Carcinogenesis, Somatic cell, Gene mutation and Loss of heterozygosity. His Cancer research is multidisciplinary, incorporating elements of Aneuploidy, Gold standard, Melanoma, Lung and Genetic heterogeneity.

The concepts of his Internal medicine study are interwoven with issues in Gastroenterology and Oncology. His Mutation study deals with the bigger picture of Genetics. Bert Vogelstein interconnects Biomarker, KRAS, GNAS complex locus and Glioma in the investigation of issues within Pathology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

Andrew P. Feinberg;Bert Vogelstein.
Analytical Biochemistry (1983)

31375 Citations

A genetic model for colorectal tumorigenesis

Eric R. Fearon;Bert Vogelstein.
Cell (1990)

15436 Citations

WAF1, a potential mediator of p53 tumor suppression

Wafik S. El-Deiry;Takashi Tokino;Victor E. Velculescu;Daniel B. Levy.
Cell (1993)

10892 Citations

p53 mutations in human cancers

Monica Hollstein;David Sidransky;Bert Vogelstein;Curtis C. Harris.
Science (1991)

10711 Citations

Genetic alterations during colorectal-tumor development.

Bert Vogelstein;Eric R. Fearon;Stanley R. Hamilton;Scott E. Kern.
The New England Journal of Medicine (1988)

8742 Citations

Surfing the p53 network

Bert Vogelstein;David Lane;Arnold J. Levine.
Nature (2000)

8544 Citations

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

Dung T. Le;Jennifer N. Uram;Hao Wang;Bjarne R. Bartlett.
The New England Journal of Medicine (2015)

7547 Citations

Cancer Genome Landscapes

Bert Vogelstein;Nickolas Papadopoulos;Victor E. Velculescu;Shibin Zhou.
Science (2013)

7383 Citations

Lessons from Hereditary Colorectal Cancer

Kenneth W Kinzler;Bert Vogelstein;Bert Vogelstein.
Cell (1996)

6477 Citations

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

D. Williams Parsons;Siân Jones;Xiaosong Zhang;Jimmy Cheng-Ho Lin.
Science (2008)

6225 Citations

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Frequent Co-Authors

External Links

Personal Website for Bert Vogelstein