D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 95 Citations 44,679 390 World Ranking 1219 National Ranking 736

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

The scientist’s investigation covers issues in Cell biology, Cellular differentiation, Wnt signaling pathway, Cancer research and Bone morphogenetic protein. His work in the fields of Cell biology, such as Mesenchymal stem cell, overlaps with other areas such as GDF2. His studies deal with areas such as RUNX2 and Stem cell as well as Cellular differentiation.

Tong-Chuan He studied Wnt signaling pathway and Cancer stem cell that intersect with Estrogen receptor, Primary tumor, Breast cancer and Triple-negative breast cancer. He combines subjects such as Carcinogenesis, Cancer, Colorectal cancer and Immunology with his study of Cancer research. His Bone morphogenetic protein study incorporates themes from Progenitor cell, Osteopontin, Bone regeneration and Achilles tendon.

His most cited work include:

  • Identification of c-MYC as a Target of the APC Pathway (4079 citations)
  • A simplified system for generating recombinant adenoviruses (3457 citations)
  • 14-3-3σ Is a p53-Regulated Inhibitor of G2/M Progression (1126 citations)

What are the main themes of his work throughout his whole career to date?

Cell biology, Cancer research, Mesenchymal stem cell, Progenitor cell and Cellular differentiation are his primary areas of study. In the field of Cell biology, his study on Stem cell, Wnt signaling pathway and Signal transduction overlaps with subjects such as GDF2. His Cancer research study combines topics in areas such as Immunology, Apoptosis, Colorectal cancer and Cell growth.

His study explores the link between Mesenchymal stem cell and topics such as Gene silencing that cross with problems in RNA interference. His research investigates the connection between Progenitor cell and topics such as Molecular biology that intersect with issues in Cell culture and HEK 293 cells. His Cellular differentiation research focuses on Internal medicine and how it connects with Oncology.

He most often published in these fields:

  • Cell biology (57.53%)
  • Cancer research (30.34%)
  • Mesenchymal stem cell (29.89%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (57.53%)
  • Mesenchymal stem cell (29.89%)
  • Cancer research (30.34%)

In recent papers he was focusing on the following fields of study:

Tong-Chuan He mostly deals with Cell biology, Mesenchymal stem cell, Cancer research, Progenitor cell and Stem cell. His Cell biology study integrates concerns from other disciplines, such as Cell, Small interfering RNA, microRNA, Gene silencing and Bone regeneration. His Mesenchymal stem cell research also works with subjects such as

  • Regeneration that connect with fields like Dental pulp stem cells, Periodontal ligament stem cells and Osteoblast,
  • Wnt signaling pathway together with Cellular differentiation.

His Cancer research research is multidisciplinary, incorporating elements of Epithelial–mesenchymal transition, Apoptosis, Protein kinase B, Cell growth and Cancer cell. The Progenitor cell study combines topics in areas such as Transplantation, Bone morphogenetic protein and Scaffold. His work focuses on many connections between Bone morphogenetic protein and other disciplines, such as Signal transduction, that overlap with his field of interest in Angiogenesis.

Between 2017 and 2021, his most popular works were:

  • Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis. (133 citations)
  • BMP9 signaling in stem cell differentiation and osteogenesis. (114 citations)
  • A pH-Triggered, Self-Assembled, and Bioprintable Hybrid Hydrogel Scaffold for Mesenchymal Stem Cell Based Bone Tissue Engineering. (33 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His scientific interests lie mostly in Cell biology, Mesenchymal stem cell, Progenitor cell, Cancer research and Bone morphogenetic protein. Within one scientific family, Tong-Chuan He focuses on topics pertaining to RNA under Cell biology, and may sometimes address concerns connected to Transcription. His biological study spans a wide range of topics, including Bone regeneration and Scaffold.

His Cancer research study combines topics from a wide range of disciplines, such as Cancer, Breast cancer, Cell cycle, Cell growth and Programmed cell death. His research in Bone morphogenetic protein intersects with topics in Notch signaling pathway, Wnt signaling pathway and Signal transduction. His Signal transduction research is multidisciplinary, incorporating perspectives in Angiogenesis and Cellular differentiation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Identification of c-MYC as a Target of the APC Pathway

Tong Chuan He;Andrew B. Sparks;Carlo Rago;Heiko Hermeking.
Science (1998)

5794 Citations

A simplified system for generating recombinant adenoviruses

Tong-Chuan He;Bert Vogelstein;Kenneth W. Kinzler.
Proceedings of the National Academy of Sciences of the United States of America (1999)

4887 Citations

14-3-3σ Is a p53-Regulated Inhibitor of G2/M Progression

Heiko Hermeking;Christoph Lengauer;Kornelia Polyak;Tong Chuan He.
Molecular Cell (1997)

1777 Citations

PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs

Tong Chuan He;Timothy A. Chan;Bert Vogelstein;Kenneth W. Kinzler.
Cell (1999)

1492 Citations

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

Patrick J. Killela;Zachary J. Reitman;Yuchen Jiao;Chetan Bettegowda.
Proceedings of the National Academy of Sciences of the United States of America (2013)

1290 Citations

OSTEOGENIC ACTIVITY OF THE FOURTEEN TYPES OF HUMAN BONE MORPHOGENETIC PROTEINS (BMPS)

Hongwei Cheng;Wei Jiang;Frank M. Phillips;Rex C. Haydon.
Journal of Bone and Joint Surgery, American Volume (2003)

1267 Citations

Analysis of human transcriptomes

Victor E Velculescu;Stephen L Madden;Lin Zhang;Alex E Lash.
Nature Genetics (1999)

945 Citations

A protocol for rapid generation of recombinant adenoviruses using the AdEasy system

Jinyong Luo;Zhong Liang Deng;Zhong Liang Deng;Xiaoji Luo;Xiaoji Luo;Ni Tang;Ni Tang.
Nature Protocols (2007)

863 Citations

Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery.

Kang Q;Kang Q;Sun Mh;Cheng H;Peng Y.
Gene Therapy (2004)

769 Citations

The first identification of lysine malonylation substrates and its regulatory enzyme

Chao Peng;Zhike Lu;Zhongyu Xie;Zhongyi Cheng.
Molecular & Cellular Proteomics (2011)

641 Citations

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