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Biology and Biochemistry

D-Index
67
Citations
31805
World Ranking
8039
National Ranking
590

Overview

Heiko Hermeking is affiliated with the German Cancer Research Center in Germany. Their scientific work spans multiple research fields, with a core focus on Biochemistry, Genetics and Molecular Biology, comprising 67 publications. Additionally, 20 publications relate to Medicine.

Their subfields of study include Molecular Biology with 42 publications, Cancer Research with 23, Oncology with 14, Immunology with 4, and Pathology and Forensic Medicine with 3. These areas frame the context for a broad range of investigations primarily centered around molecular and cellular aspects of cancer.

The main topics of research covered by Heiko Hermeking include:

  • MicroRNA in disease regulation
  • RNA modifications and cancer
  • Circular RNAs in diseases
  • Cancer-related molecular mechanisms research
  • RNA Research and Splicing
  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics

Heiko Hermeking has contributed to the scientific literature through various frequent publication venues, including:

  • Cancers (6 publications)
  • Cell Death and Differentiation (3 publications)
  • Cellular and Molecular Gastroenterology and Hepatology (2 publications)
  • International Journal of Biological Sciences (2 publications)
  • Nature Communications (1 publication)

Highlighted recent papers illustrate the scope of their research:

  • "Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells," 2021, Nature Communications
  • "Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis," 2023, Cell Death and Differentiation
  • "Characterization of a p53/miR-34a/CSF1R/STAT3 Feedback Loop in Colorectal Cancer," 2020, Cellular and Molecular Gastroenterology and Hepatology
  • "AP4 suppresses DNA damage, chromosomal instability and senescence via inducing MDC1/Mediator of DNA damage Checkpoint 1 and repressing MIR22HG/miR-22-3p," 2022, Molecular Cancer
  • "Additive contribution of microRNA-34a/b/c to human arterial ageing and atherosclerosis," 2021, Atherosclerosis

Frequent collaborators have included Matjaž Rokavec (16 joint works), Markus Kaller (11), Jens Neumann (5), Nassim Bouznad (4), and Zekai Huang (4). These collaborations indicate active involvement in teamwork across related research topics.

Best Publications

  • Identification of c-MYC as a Target of the APC Pathway

    Tong Chuan He;Andrew B. Sparks;Carlo Rago;Heiko Hermeking

  • 14-3-3σ Is a p53-Regulated Inhibitor of G2/M Progression

    Heiko Hermeking;Christoph Lengauer;Kornelia Polyak;Tong Chuan He

  • The miR-34 family in cancer and apoptosis.

    H Hermeking

  • 14-3-3σ is required to prevent mitotic catastrophe after DNA damage

    Timothy A. Chan;Heiko Hermeking;Christoph Lengauer;Kenneth W. Kinzler

  • Differential Regulation of microRNAs by p53 Revealed by Massively Parallel Sequencing: miR-34a is a p53 Target That Induces Apoptosis and G1-arrest

    Valery Tarasov;Peter Jung;Berlinda Verdoodt;Dmitri Lodygin

  • Mediation of c-Myc-induced apoptosis by p53.

    Heiko Hermeking;Dirk Eick

  • Analysis of human transcriptomes

    Victor E Velculescu;Stephen L Madden;Lin Zhang;Alex E Lash

  • Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer.

    Dmitri Lodygin;Valery Tarasov;Alexey Epanchintsev;Carola Berking

  • MicroRNA-34a regulates cardiac ageing and function

    Reinier A. Boon;Kazuma Iekushi;Stefanie Lechner;Timon Seeger

  • IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

    Matjaz Rokavec;Meryem Gülfem Öner;Huihui Li;Rene Jackstadt

  • miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions.

    Helge Siemens;Rene Jackstadt;Sabine Hünten;Markus Kaller

  • p53 enters the MicroRNA world

    Heiko Hermeking

  • The 14-3-3 cancer connection

    Heiko Hermeking

  • Identification of CDK4 as a target of c-MYC.

    Heiko Hermeking;Carlo Rago;Marino Schuhmacher;Qing Li

  • MicroRNAs in the p53 network: micromanagement of tumour suppression.

    Heiko Hermeking

  • High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer

    Anne T. Ferguson;Ella Evron;Christopher B. Umbricht;Tej K. Pandita

  • Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes

    Antje Menssen;Heiko Hermeking

  • 14-3-3 proteins in cell cycle regulation

    Heiko Hermeking;Anne Benzinger

  • Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas

    Markus Vogt;Johanna Munding;Martha Grüner;Sven-Thorsten Liffers

  • Frequent Downregulation of miR-34 Family in Human Ovarian Cancers

    David C. Corney;Chang Il Hwang;Andres Matoso;Markus Vogt

Frequent Co-Authors

Andreas Jung
Andreas Jung University of Zurich
Bert Vogelstein
Bert Vogelstein Johns Hopkins University
Dirk Eick
Dirk Eick Center for Integrated Protein Science Munich
Kenneth W. Kinzler
Kenneth W. Kinzler Johns Hopkins University
Andreas M. Zeiher
Andreas M. Zeiher Goethe University Frankfurt
Hiroki Yoshida
Hiroki Yoshida Saga University
John R. Yates
John R. Yates Scripps Research Institute
Atsushi Hirao
Atsushi Hirao Kanazawa University
Paul M. Hwang
Paul M. Hwang National Institutes of Health
Timothy A. Chan
Timothy A. Chan Cleveland Clinic

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