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Biology and Biochemistry

D-Index
82
Citations
23575
World Ranking
3709
National Ranking
1843

Overview

Rex C. Haydon is affiliated with the University of Chicago in the United States and has a significant body of research contributions primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields, including Molecular Biology, Cancer Research, Surgery, Pulmonary and Respiratory Medicine, and Genetics.

Haydon's research focuses on various topics that frequently intersect cancer biology and molecular mechanisms. These main topics include:

  • Cancer-related molecular mechanisms research
  • Tissue Engineering and Regenerative Medicine
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Electrospun Nanofibers in Biomedical Applications
  • Wnt/β-catenin signaling in development and cancer
  • MicroRNA in disease regulation

Many of Haydon's publications appear in the journal Genes & Diseases, which is their most frequent publication venue, along with contributions to Aging, Molecular Oncology, Nucleic Acids Research, and Bioactive Materials. Their research presence in Genes & Diseases is notable with at least 17 publications. Other venues include Aging with two publications and single papers in Molecular Oncology, Nucleic Acids Research, and Bioactive Materials.

Among recent prominent papers by Haydon are:

  • Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk (2023, Genes & Diseases)
  • The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities (2023, Genes & Diseases)
  • Ferroptosis as a novel form of regulated cell death: Implications in the pathogenesis, oncometabolism and treatment of human cancer (2020, Genes & Diseases)
  • Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance (2022, Genes & Diseases)
  • Long noncoding RNA (lncRNA) H19: An essential developmental regulator with expanding roles in cancer, stem cell differentiation, and metabolic diseases (2023, Genes & Diseases)

Collaborations have been an integral part of their scientific output. Frequent coauthors include Tong-Chuan He, Hue H. Luu, Russell R. Reid, William Wagstaff, and Jiaming Fan, reflecting ongoing partnerships within their research network.

Best Publications

  • OSTEOGENIC ACTIVITY OF THE FOURTEEN TYPES OF HUMAN BONE MORPHOGENETIC PROTEINS (BMPS)

    Hongwei Cheng;Wei Jiang;Frank M. Phillips;Rex C. Haydon

  • Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis.

    Yixiao Feng;Yixiao Feng;Mia Spezia;Shifeng Huang;Shifeng Huang;Chengfu Yuan;Chengfu Yuan

  • Bone Morphogenetic Protein (BMP) signaling in development and human diseases.

    Richard N. Wang;Jordan Green;Zhongliang Wang;Youlin Deng

  • A protocol for rapid generation of recombinant adenoviruses using the AdEasy system

    Jinyong Luo;Zhong Liang Deng;Zhong Liang Deng;Xiaoji Luo;Xiaoji Luo;Ni Tang;Ni Tang

  • Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery.

    Kang Q;Kang Q;Sun Mh;Cheng H;Peng Y

  • DISTINCT ROLES OF BONE MORPHOGENETIC PROTEINS IN OSTEOGENIC DIFFERENTIATION OF MESENCHYMAL STEM CELLS

    Hue H. Luu;Wen Xin Song;Xiaoji Luo;Xiaoji Luo;David Manning

  • Regulation of osteogenic differentiation during skeletal development.

    Zhong Liang Deng;Katie A. Sharff;Ni Tang;Ni Tang;Wen Xin Song

  • A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells.

    Quan Kang;Wen-Xin Song;Wen-Xin Song;Qing Luo;Qing Luo;Ni Tang;Ni Tang;Ni Tang

  • Wnt/beta-catenin signaling pathway as a novel cancer drug target.

    Hue H. Luu;Ruiwen Zhang;Rex C. Haydon;Elizabeth Rayburn

  • Osteosarcoma development and stem cell differentiation.

    Ni Tang;Wen-Xin Song;Jinyong Luo;Jinyong Luo;Rex C. Haydon

  • Wnt signaling in bone formation and its therapeutic potential for bone diseases

    Jeong Hwan Kim;Xing Liu;Jinhua Wang;Xiang Chen

  • Connective Tissue Growth Factor (CTGF) Is Regulated by Wnt and Bone Morphogenetic Proteins Signaling in Osteoblast Differentiation of Mesenchymal Stem Cells

    Qing Luo;Quan Kang;Quan Kang;Weike Si;Weike Si;Wei Jiang

  • The versatile functions of Sox9 in development, stem cells, and human diseases.

    Alice Jo;Sahitya K. Denduluri;Bosi Zhang;Zhongliang Wang

  • CCN1/Cyr61 Is Regulated by the Canonical Wnt Signal and Plays an Important Role in Wnt3A-Induced Osteoblast Differentiation of Mesenchymal Stem Cells

    Weike Si;Quan Kang;Quan Kang;Hue H. Luu;Jong Kyung Park;Jong Kyung Park

  • Potential use of Sox9 gene therapy for intervertebral degenerative disc disease.

    Ronjon Paul;Rex C. Haydon;Hongwei Cheng;Akira Ishikawa

  • BMP signaling in mesenchymal stem cell differentiation and bone formation.

    Maureen Beederman;Joseph D. Lamplot;Guoxin Nan;Jinhua Wang

  • Insulin-like Growth Factor 2 (IGF-2) Potentiates BMP-9-Induced Osteogenic Differentiation and Bone Formation

    Liang Chen;Wei Jiang;Jiayi Huang;Jiayi Huang;Bai-Cheng He;Bai-Cheng He

  • BMP‐9‐induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/β‐catenin signalling

    Ni Tang;Wen‐Xin Song;Jinyong Luo;Jinyong Luo;Xiaoji Luo;Xiaoji Luo

  • Mesenchymal stem cells: Molecular characteristics and clinical applications

    Farbod Rastegar;Deana Shenaq;Jiayi Huang;Wenli Zhang

  • Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)1

    H Cheng;W Jiang;F.M Phillips;R.C Haydon

Frequent Co-Authors

Tong-Chuan He
Tong-Chuan He University of Chicago
Hue H. Luu
Hue H. Luu University of Chicago
Yang Bi
Yang Bi Chongqing Medical University
Wei Jiang
Wei Jiang Wuhan University

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