Kevin Karplus

Overview

Best Publications

• Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega

  Fabian Sievers;Andreas Wilm;David Dineen;Toby J Gibson

  17346
  Citations

• Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8.

  Elmar Krieger;Keehyoung Joo;Jinwoo Lee;Jooyoung Lee

  1555
  Citations

• Hidden Markov models for detecting remote protein homologies.

  Kevin Karplus;Christian Barrett;Richard Hughey

  1504
  Citations

• Sequence comparisons using multiple sequences detect three times as many remote homologues as pairwise methods.

  Jong Park;Kevin Karplus;Christian Barrett;Richard Hughey

  714
  Citations

• Automated forward and reverse ratcheting of DNA in a nanopore at 5-A precision

  Gerald M Cherf;Kate R Lieberman;Hytham Rashid;Christopher E Lam

  709
  Citations

• Digital Synthesis of Plucked-String and Drum Timbers

  Kevin Karplus;Alex Strong

  596
  Citations

• DIRICHLET MIXTURES: A METHOD FOR IMPROVING DETECTION OF WEAK BUT SIGNIFICANT PROTEIN SEQUENCE HOMOLOGY

  Kimmen Sjolander;Kevin Karplus;Michael Brown;Richard Hughey

  480
  Citations

• A flexible motif search technique based on generalized profiles

  Philipp Bucher;Kevin Karplus;Nicolas Moeri;Kay Hofmann

  411
  Citations

• Classifying G-protein coupled receptors with support vector machines

  Rachel Karchin;Kevin Karplus;David Haussler

  387
  Citations

• Combining local‐structure, fold‐recognition, and new fold methods for protein structure prediction

  Kevin Karplus;Rachel Karchin;Jenny Draper;Jonathan Casper

  373
  Citations

• Hidden Markov models that use predicted local structure for fold recognition: alphabets of backbone geometry.

  Rachel Karchin;Melissa Cline;Yael Mandel-Gutfreund;Kevin Karplus

  261
  Citations

• CAFASP‐1: Critical assessment of fully automated structure prediction methods

  Daniel Fischer;Christian Barret;Kevin Bryson;Arne Elofsson

  233
  Citations

• Predicting protein structure using only sequence information

  Kevin Karplus;Christian Barrett;Melissa Cline;Mark Diekhans

  188
  Citations

• SAM-T08, HMM-based protein structure prediction.

  Kevin Karplus

  184
  Citations

• Xmap: A technology mapper for table-lookup field-programmable gate arrays

  Kevin Karplus

  177
  Citations

• Contact prediction using mutual information and neural nets

  George Shackelford;Kevin Karplus

  173
  Citations

• Scoring hidden Markov models

  Christian Barrett;Richard Hughey;Kevin Karplus

  153
  Citations

• Predicting reliable regions in protein sequence alignments.

  Melissa S. Cline;Richard Hughey;Kevin Karplus

  146
  Citations

• SAM-T04: what is new in protein-structure prediction for CASP6.

  Kevin Karplus;Sol Katzman;George Shackleford;Martina Koeva

  141
  Citations

• Evaluation of protein multiple alignments by SAM-T99 using the BAliBASE multiple alignment test set.

  Kevin Karplus;Birong Hu

  139
  Citations