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Genetics

D-Index
66
Citations
36454
World Ranking
2562
National Ranking
1138

Overview

Dmitry A. Gordenin is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on the broad field of biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology, cancer research, plant science, genetics, and pulmonary and respiratory medicine.

The scientist has contributed extensively to topics including cancer genomics and diagnostics, DNA repair mechanisms, epigenetics and DNA methylation, CRISPR and genetic engineering, RNA modifications and cancer, chromosomal and genetic variations, and genomics and chromatin dynamics.

Dmitry A. Gordenin has been involved in multiple publications, frequently appearing in venues such as UNC Libraries, Nature Genetics, Nature, bioRxiv (Cold Spring Harbor Laboratory), and Nature Communications.

Recent notable papers include:

  • The repertoire of mutational signatures in human cancer (2020, Nature)
  • Patterns of somatic structural variation in human cancer genomes (2020, Nature)
  • Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing (2020, Nature Genetics)
  • Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition (2020, Nature Genetics)
  • Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer (2020, Nature Genetics)

The scientist has collaborated frequently with several coauthors, including Leszek J. Klimczak, Kadir C. Akdemir, Steven A. Roberts, Peter J. Park, and Natalie Saini, reflecting sustained teamwork in various research projects.

Best Publications

  • Mutational heterogeneity in cancer and the search for new cancer-associated genes

    Michael S. Lawrence;Petar Stojanov;Petar Stojanov;Paz Polak;Paz Polak;Paz Polak;Gregory V. Kryukov;Gregory V. Kryukov;Gregory V. Kryukov

  • Comprehensive molecular characterization of urothelial bladder carcinoma

    John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • The Repertoire of Mutational Signatures in Human Cancer

    Ludmil B Alexandrov;Jaegil Kim;Nicholas J Haradhvala;Nicholas J Haradhvala;Mi Ni Huang

  • Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

    A. Gordon Robertson;Jaegil Kim;Hikmat Al-Ahmadie;Joaquim Bellmunt

  • An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

    Steven A Roberts;Michael S Lawrence;Leszek J Klimczak;Sara A Grimm

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma

    Caleb F. Davis;Christopher J. Ricketts;Min Wang;Lixing Yang

  • Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

    Isidro Cortés-Ciriano;Jake June-Koo Lee;Ruibin Xi;Dhawal Jain

  • Cadmium is a mutagen that acts by inhibiting mismatch repair

    Yong Hwan Jin;Alan B Clark;Robbert J C Slebos;Hanan Al-Refai

  • Division of Labor at the Eukaryotic Replication Fork

    Stephanie A. Nick McElhinny;Dmitry A. Gordenin;Carrie M. Stith;Peter M.J. Burgers

  • Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.

    Bernardo Rodriguez-Martin;Bernardo Rodriguez-Martin;Eva G. Alvarez;Eva G. Alvarez;Adrian Baez-Ortega;Jorge Zamora

  • The Mre11 Complex Is Required for Repair of Hairpin-Capped Double-Strand Breaks and Prevention of Chromosome Rearrangements

    Kirill S. Lobachev;Dmitry A. Gordenin;Michael A. Resnick

  • Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions

    Steven A. Roberts;Joan Sterling;Cole Thompson;Shawn Harris

  • Hypermutation in human cancer genomes: footprints and mechanisms

    Steven A. Roberts;Steven A. Roberts;Dmitry A. Gordenin

  • An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

    Kin Chan;Steven A Roberts;Steven A Roberts;Leszek J Klimczak;Joan F Sterling

  • Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.

    H T Tran;J D Keen;M Kricker;M A Resnick

  • Okazaki Fragment Maturation in Yeast I. DISTRIBUTION OF FUNCTIONS BETWEEN FEN1 AND DNA2

    Rao Ayyagari;Xavier V. Gomes;Dmitry A. Gordenin;Peter M.J. Burgers

  • Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency.

    Carolyn D Hurst;Olivia Alder;Fiona M Platt;Alastair Droop

  • Repeat expansion--all in a flap?

    Dmitry A. Gordenin;Thomas A. Kunkel;Michael A. Resnick

Frequent Co-Authors

Michael A. Resnick
Michael A. Resnick National Institutes of Health
Gad Getz
Gad Getz Broad Institute
Piotr A. Mieczkowski
Piotr A. Mieczkowski University of North Carolina at Chapel Hill
Thomas A. Kunkel
Thomas A. Kunkel National Institutes of Health
Peter J. Park
Peter J. Park Harvard University
David J. Kwiatkowski
David J. Kwiatkowski Brigham and Women's Hospital
Katherine A. Hoadley
Katherine A. Hoadley University of North Carolina at Chapel Hill
Peter W. Laird
Peter W. Laird Van Andel Institute
David C. Wedge
David C. Wedge University of Manchester
Gregory V. Kryukov
Gregory V. Kryukov Broad Institute

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