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Genetics

D-Index
79
Citations
55143
World Ranking
1605
National Ranking
208

Medicine

D-Index
79
Citations
55148
World Ranking
17334
National Ranking
1565

Overview

Peter Van Loo is affiliated with The Francis Crick Institute in the United Kingdom. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with significant work also in Medicine. The scientist's study emphasizes Cancer Research, Molecular Biology, Genetics, Oncology, and Pulmonary and Respiratory Medicine.

Van Loo's work covers a wide range of topics related to cancer and genetics. These include Cancer Genomics and Diagnostics, Genomic variations and chromosomal abnormalities, RNA modifications and cancer, Genomics and Phylogenetic Studies, Epigenetics and DNA Methylation, Genomics and Rare Diseases, and Cancer-related molecular mechanisms research.

Several of Van Loo's recent papers demonstrate this focus, including:

  • Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition, 2021, Cell
  • Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes, 2021, Cell
  • Signatures of copy number alterations in human cancer, 2022, Nature
  • Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition, 2020, Nature Genetics
  • Pervasive chromosomal instability and karyotype order in tumour evolution, 2020, Nature

Van Loo frequently collaborates with other researchers. Key co-authors include Jonas Demeulemeester, Maxime Tarabichi, Tom Lesluyes, Charles Swanton, and Stefan C. Dentro. This network reflects a collaborative approach to research in cancer genomics.

The scientist's work has been published extensively in several journals and platforms. Notable venues with multiple publications by Van Loo are Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Nature, Nature Communications, and Blood.

Best Publications

  • Genomic Classification and Prognosis in Acute Myeloid Leukemia

    Elli Papaemmanuil;Moritz Gerstung;Lars Bullinger;Verena I Gaidzik

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Tracking the Evolution of Non–Small-Cell Lung Cancer

    Mariam Jamal-Hanjani;Gareth A. Wilson;Nicholas McGranahan;Nicolai Juul Birkbak

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Mutational Processes Molding the Genomes of 21 Breast Cancers

    Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • Clinical and biological implications of driver mutations in myelodysplastic syndromes.

    Elli Papaemmanuil;Moritz Gerstung;Luca Malcovati;Sudhir Tauro

  • Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

    Christopher Abbosh;Nicolai J. Birkbak;Nicolai J. Birkbak;Gareth A. Wilson;Gareth A. Wilson;Mariam Jamal-Hanjani

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • High burden and pervasive positive selection of somatic mutations in normal human skin

    Iñigo Martincorena;Amit Roshan;Moritz Gerstung;Peter Ellis

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

  • The evolutionary history of lethal metastatic prostate cancer.

    Gunes Gundem;Peter Van Loo;Peter Van Loo;Peter Van Loo;Barbara Kremeyer;Ludmil B. Alexandrov

  • Universal Patterns of Selection in Cancer and Somatic Tissues

    Iñigo Martincorena;Keiran M. Raine;Moritz Gerstung;Kevin J. Dawson

  • Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

    Nicholas McGranahan;Rachel Rosenthal;Crispin T. Hiley;Crispin T. Hiley;Andrew J. Rowan

  • Allele-specific copy number analysis of tumors

    Peter Van Loo;Silje H. Nordgard;Silje H. Nordgard;Ole Christian Lingjærde;Hege G. Russnes

  • Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

    Elza C. de Bruin;Nicholas McGranahan;Nicholas McGranahan;Richard Mitter;Max Salm

  • Gene prioritization through genomic data fusion.

    Stein Aerts;Diether Lambrechts;Sunit Maity;Peter Van Loo

  • Mutational signatures associated with tobacco smoking in human cancer

    Ludmil B Alexandrov;Ludmil B Alexandrov;Young Seok Ju;Kerstin Haase;Peter Van Loo;Peter Van Loo

  • The evolutionary history of 2,658 cancers

    Moritz Gerstung;Moritz Gerstung;Clemency Jolly;Ignaty Leshchiner;Stefan C Dentro;Stefan C Dentro;Stefan C Dentro

  • Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

    Niccolo Bolli;Hervé Avet-Loiseau;David C. Wedge;Peter Van Loo

  • Subclonal diversification of primary breast cancer revealed by multiregion sequencing

    Lucy R. Yates;Moritz Gerstung;Stian Knappskog;Christine Desmedt

Frequent Co-Authors

Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
David C. Wedge
David C. Wedge University of Manchester
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Anne Lise Børresen-Dale
Anne Lise Børresen-Dale Oslo University Hospital
Ludmil B. Alexandrov
Ludmil B. Alexandrov University of California, San Diego
Keiran Raine
Keiran Raine Wellcome Sanger Institute
Moritz Gerstung
Moritz Gerstung German Cancer Research Center
Vessela N. Kristensen
Vessela N. Kristensen Oslo University Hospital
Paul C. Boutros
Paul C. Boutros University of California, Los Angeles

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