What is he best known for?
The fields of study he is best known for:
John A. Hassell mostly deals with Molecular biology, Cancer research, Transcription factor, Cell biology and ETS transcription factor family.
In his study, Mammary gland is strongly linked to Gene, which falls under the umbrella field of Molecular biology.
His research in Cancer research intersects with topics in Cancer stem cell, Glial cell line-derived neurotrophic factor, Neurotrophic factors, Immunology and In vivo.
The Transcription factor study combines topics in areas such as Promoter, Response element, Gene expression and Transcription.
His research in the fields of Sonic hedgehog overlaps with other disciplines such as Apical ectodermal ridge.
His research integrates issues of Carcinogenesis and Receptor tyrosine kinase, Kinase in his study of ETS transcription factor family.
His most cited work include:
- Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction (366 citations)
- Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells (327 citations)
- Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells. (264 citations)
What are the main themes of his work throughout his whole career to date?
John A. Hassell mainly investigates Molecular biology, Cancer research, Breast cancer, Cell biology and Transcription factor.
His biological study spans a wide range of topics, including Plasmid, Transcription, Gene, DNA and Antigen.
John A. Hassell has included themes like Carcinogenesis, Immunology, Receptor, Stem cell and In vivo in his Cancer research study.
John A. Hassell has researched Carcinogenesis in several fields, including Genetically modified mouse, Transgene and Mammary gland.
His Breast cancer research is multidisciplinary, incorporating elements of Oncology and Gene expression profiling.
His Transcription factor research focuses on Gene expression and how it relates to Signal transduction.
He most often published in these fields:
- Molecular biology (34.03%)
- Cancer research (26.39%)
- Breast cancer (17.36%)
What were the highlights of his more recent work (between 2015-2021)?
- Cancer research (26.39%)
- Breast cancer (17.36%)
- Cancer (13.19%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Cancer research, Breast cancer, Cancer, Triple-negative breast cancer and Pharmacology.
His Cancer research study incorporates themes from Metastasis, Brain metastasis, Gene knockdown, Receptor and Brain tumor.
In his work, Transforming growth factor and Cancer cell is strongly intertwined with Carcinogenesis, which is a subfield of Metastasis.
His Breast cancer research is multidisciplinary, incorporating perspectives in Cytotoxic T cell, Oncology, In vivo and Gene expression profiling.
His In vivo research integrates issues from Cell culture, Protein kinase B, PI3K/AKT/mTOR pathway and Mechanism of action.
His Triple-negative breast cancer research incorporates themes from Immunology and Cell growth.
Between 2015 and 2021, his most popular works were:
- Claudin-Low Breast Cancer; Clinical & Pathological Characteristics (53 citations)
- CD133 + brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence (30 citations)
- Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours (23 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Breast cancer, Cancer, Cancer research, Metastasis and Serotonin Antagonists.
His study explores the link between Breast cancer and topics such as Cytotoxic T cell that cross with problems in Immunotherapy.
In most of his Cancer studies, his work intersects topics such as Immunology.
His Cancer research research is multidisciplinary, incorporating elements of Carcinogenesis, Brain tumor, Pathology and Adenocarcinoma.
His Carcinogenesis research includes elements of Cancer cell, Transforming growth factor and Growth factor receptor.
His Chemotherapy research is multidisciplinary, incorporating perspectives in Cell cycle, Stem cell and Medulloblastoma.
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