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Biology and Biochemistry

D-Index
67
Citations
11043
World Ranking
8414
National Ranking
3787

Overview

Luis Del Valle is affiliated with Louisiana State University Health Sciences Center New Orleans in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Oncology, Immunology, Genetics, and Cancer Research as significant subfields of study.

The research topics that Luis Del Valle has contributed to include:

  • Epigenetics and DNA Methylation
  • Cancer Cells and Metastasis
  • Immune cells in cancer
  • Virus-based gene therapy research
  • Cancer Immunotherapy and Biomarkers
  • Cancer Research and Treatments
  • Viral-associated cancers and disorders

Several recent papers illustrate the scope and focus of their work. These include:

  • "Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer," published in 2021 in the Journal for ImmunoTherapy of Cancer
  • "Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells," published in 2021 in Frontiers in Immunology
  • "Pathogenesis and Mechanisms of SARS-CoV-2 Infection in the Intestine, Liver, and Pancreas," published in 2023 in Cells
  • "A Phase Ib Dose Escalation Trial of RO4929097 (a γ-secretase inhibitor) in Combination with Exemestane in Patients with ER + Metastatic Breast Cancer (MBC)," published in 2021 in Clinical Breast Cancer
  • "Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor," published in 2020 in PLoS ONE

The frequent co-authors collaborating with Luis Del Valle are:

  • Jovanny Zabaleta
  • Lucio Miele
  • Dorota Wyczechowska
  • Augusto C. Ochoa
  • Samarpan Majumder

The primary publication venues for Luis Del Valle include:

  • Methods in molecular biology
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Viruses
  • Frontiers in Immunology

Best Publications

  • Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies

    Fokhrul Hossain;Amir A. Al-Khami;Dorota Wyczechowska;Claudia Hernandez

  • Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells

    Amir A. Al-Khami;Liqin Zheng;Luis Del Valle;Fokhrul Hossain

  • Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice.

    Ganesh Rao;Carolyn A Pedone;Luis Del Valle;Krzysztof Reiss

  • Association of human polyomavirus JCV with colon cancer: evidence for interaction of viral T-antigen and beta-catenin.

    Sahnila Enam;Luis Del Valle;César Lara;Dai-Di Gan

  • The Stress-Response Sensor Chop Regulates the Function and Accumulation of Myeloid-Derived Suppressor Cells in Tumors

    Paul T. Thevenot;Rosa A. Sierra;Patrick L. Raber;Amir A. Al-Khami

  • Purα Is Essential for Postnatal Brain Development and Developmentally Coupled Cellular Proliferation As Revealed by Genetic Inactivation in the Mouse

    Kamel Khalili;Luis Del Valle;Vandhana Muralidharan;William J. Gault

  • Detection of human neurotropic JC virus DNA sequence and expression of the viral oncogenic protein in pediatric medulloblastomas.

    Barbara Krynska;Luis Del Valle;Sidney Croul;Jennifer Gordon

  • Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies

    Amir A Al-Khami;Fokhrul Hossain;Dorota Wyczechowska;Claudia Hernandez

  • Detection of JC Virus DNA Sequences and Expression of the Viral Regulatory Protein T-Antigen in Tumors of the Central Nervous System

    Luis Del Valle;Jennifer Gordon;Martha Assimakopoulou;Sahnila Enam

  • Human neurotropic polyomavirus, JCV, and its role in carcinogenesis.

    Kamel Khalili;Luis Del Valle;Jessica Otte;Michael Weaver

  • Spinal cord histopathological alterations in a patient with longstanding complex regional pain syndrome.

    Luis Del Valle;Robert J. Schwartzman;Guillermo Alexander

  • Detection of HIV-1 Tat and JCV capsid protein, VP1, in AIDS brain with progressive multifocal leukoencephalopathy

    Luis Del Valle;Sidney Croul;Susan Morgello;Shohreh Amini

  • Interaction of α9β1 Integrin With Thrombospondin-1 Promotes Angiogenesis

    Izabela Staniszewska;Shachi Zaveri;Luis Del Valle;Isabela Oliva

  • Activation of the Oxidative Stress Pathway by HIV-1 Vpr Leads to Induction of Hypoxia-inducible Factor 1α Expression

    Satish L. Deshmane;Ruma Mukerjee;Shongshan Fan;Luis Del Valle

  • Expression of Human Neurotropic Polyomavirus JCV Late Gene Product Agnoprotein in Human Medulloblastoma

    Luis Del Valle;Jennifer Gordon;Sahnila Enam;Serena Delbue

  • Evidence for involvement of Wnt signaling pathway in IB-MECA mediated suppression of melanoma cells

    Pnina Fishman;Lea Madi;Sara Bar-Yehuda;Faina Barer

  • Role of the Insulin-Like Growth Factor I/Insulin Receptor Substrate 1 Axis in Rad51 Trafficking and DNA Repair by Homologous Recombination

    Joanna Trojanek;Thu Ho;Luis Del Valle;Michal Nowicki

  • Insulin receptor substrate 1 translocation to the nucleus by the human JC virus T-antigen.

    Adam Lassak;Luis Del Valle;Francesca Peruzzi;Jin Ying Wang

  • Detection of JC Virus DNA Fragments but Not Proteins in Normal Brain Tissue

    Georgina Perez-Liz;Georgina Perez-Liz;Luis Del Valle;Luis Del Valle;Antonio Gentilella;Antonio Gentilella;Sidney Croul;Sidney Croul

  • Insulin-like Growth Factor I Receptor Activity in Human Medulloblastomas

    Luis Del Valle;Sahnila Enam;Adam Lassak;Jin Yiang Wang

Frequent Co-Authors

Kamel Khalili
Kamel Khalili Temple University
Krzysztof Reiss
Krzysztof Reiss Louisiana State University Health Sciences Center New Orleans
Shohreh Amini
Shohreh Amini Temple University
Paulo C. Rodriguez
Paulo C. Rodriguez Moffitt Cancer Center
Antonio Giordano
Antonio Giordano Temple University
Jay Rappaport
Jay Rappaport Tulane University
Philip Lazarovici
Philip Lazarovici Hebrew University of Jerusalem
Benjamin B. Gelman
Benjamin B. Gelman The University of Texas Medical Branch at Galveston
George P. Tuszynski
George P. Tuszynski Temple University
Bruce A. Bunnell
Bruce A. Bunnell University of North Texas Health Science Center

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