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Biology and Biochemistry

D-Index
51
Citations
12533
World Ranking
17003
National Ranking
7009

Overview

Shohreh Amini is affiliated with Temple University in the United States and has contributed extensively to research in medicine, biochemistry, genetics, and molecular biology. Their body of work encompasses a variety of subfields, including molecular biology, pediatrics, perinatology and child health, obstetrics and gynecology, virology, and cancer research.

The scientist's research topics include prenatal substance exposure effects, pregnancy and preeclampsia studies, HIV research and treatment, CRISPR and genetic engineering, neonatal and fetal brain pathology, HIV/AIDS drug development and treatment, and investigations into heme oxygenase-1 and carbon monoxide.

Recent papers authored or co-authored by Shohreh Amini include the following:

  • CRISPR editing of CCR5 and HIV-1 facilitates viral elimination in antiretroviral drug-suppressed virus-infected humanized mice, 2023, Proceedings of the National Academy of Sciences
  • General Overview of Neuronal Cell Culture, 2021, Methods in Molecular Biology
  • Nuclear translocation of Gasdermin D sensitizes colorectal cancer to chemotherapy in a pyroptosis-independent manner, 2022, Oncogene
  • The lncRNA LOC102549805 (U1) modulates neurotoxicity of HIV-1 Tat protein, 2020, Cell Death and Disease
  • HIV-1 and HIV-1-Tat Induce Mitochondrial DNA Damage in Human Neurons, 2020, Journal of HIV and AIDS

Frequent co-authors collaborating with Shohreh Amini include:

  • Nune Darbinian
  • Armine Darbinyan
  • Nana Merabova
  • Laura Goetzl
  • Michael E. Selzer

Publications by Shohreh Amini have appeared multiple times in the following venues, indicating ongoing research relationships:

  • Obstetrics and Gynecology Research (4 publications)
  • International Journal of Molecular Sciences (3 publications)
  • Journal of HIV and AIDS (2 publications)
  • Proceedings of the National Academy of Sciences (1 publication)
  • Methods in Molecular Biology (1 publication)

Amini has also contributed to book publications, including a work published by Springer Science+Business Media titled Neuronal Cell Culture in 2021.

The research focus spans medical studies that explore molecular mechanisms relevant to prenatal health, neurotoxicity, HIV pathogenesis, and cancer treatment responses, among other areas. This interdisciplinary approach combines experimental and clinical perspectives aligned with contemporary challenges in genetics and molecular biology.

Best Publications

  • Monocyte chemoattractant protein-1 (MCP-1): an overview.

    Satish L. Deshmane;Sergey Kremlev;Shohreh Amini;Bassel E. Sawaya

  • CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection

    Tracy Fischer-Smith;Sidney Croul;Andrij E. Sverstiuk;Christelle Capini

  • Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice

    Prasanta K. Dash;Rafal Kaminski;Ramona Bella;Hang Su

  • HIV-1 associated dementia: symptoms and causes

    Mohammad Ghafouri;Shohreh Amini;Kamel Khalili;Bassel E Sawaya

  • General Overview of Neuronal Cell Culture

    Jennifer Gordon;Shohreh Amini;Martyn K. White

  • Purα Is Essential for Postnatal Brain Development and Developmentally Coupled Cellular Proliferation As Revealed by Genetic Inactivation in the Mouse

    Kamel Khalili;Luis Del Valle;Vandhana Muralidharan;William J. Gault

  • Mitochondrial quality control in cardiac cells: Mechanisms and role in cardiac cell injury and disease.

    Farzaneh G. Tahrir;Dianne Langford;Shohreh Amini;Taha Mohseni Ahooyi

  • Trans-activation of the JC virus late promoter by the tat protein of type 1 human immunodeficiency virus in glial cells

    Hiroomi Tada;Jay Rappaport;Monir Lashgari;Shohreh Amini

  • Molecular pathway involved in HIV-1-induced CNS pathology: role of viral regulatory protein, Tat.

    J Rappaport;J Joseph;S Croul;G Alexander

  • Detection of HIV-1 Tat and JCV capsid protein, VP1, in AIDS brain with progressive multifocal leukoencephalopathy

    Luis Del Valle;Sidney Croul;Susan Morgello;Shohreh Amini

  • Cooperative Interaction between HIV-1 Regulatory Proteins Tat and Vpr Modulates Transcription of the Viral Genome

    Bassel E. Sawaya;Kamel Khalili;Jennifer Gordon;Ran Taube

  • Activation of the Oxidative Stress Pathway by HIV-1 Vpr Leads to Induction of Hypoxia-inducible Factor 1α Expression

    Satish L. Deshmane;Ruma Mukerjee;Shongshan Fan;Luis Del Valle

  • Cooperative Actions of HIV-1 Vpr and p53 Modulate Viral Gene Transcription

    Bassel E. Sawaya;Kamel Khalili;W. Edward Mercer;Lyudmila Denisova

  • TAR-independent transactivation by Tat in cells derived from the CNS: a novel mechanism of HIV-1 gene regulation.

    J.P. Taylor;R. Pomerantz;O. Bagasra;M. Chowdhury

  • HIV-1 Nef is released in extracellular vesicles derived from astrocytes: evidence for Nef-mediated neurotoxicity.

    A Sami Saribas;Stephanie Cicalese;Taha Mohseni Ahooyi;Kamel Khalili

  • Evidence for stimulation of the transforming growth factor beta 1 promoter by HIV-1 Tat in cells derived from CNS

    C. Cupp;J. P. Taylor;Kamel Khalili;Shohreh Amini

  • A 39-kD DNA-binding Protein from Mouse Brain Stimulates Transcription of Myelin Basic Protein Gene in Oligodendrocytic Cells

    S. Haas;Prakash Thatikunta;A. Steplewski;E. M. Johnson

  • Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells.

    J P Taylor;C Cupp;A Diaz;M Chowdhury

  • HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis.

    Carlos A. Barrero;Prasun K. Datta;Satarupa Sen;Satish Deshmane

  • Role of JC Virus Agnoprotein in DNA Repair

    Armine Darbinyan;Khwaja M. Siddiqui;Dorota Slonina;Nune Darbinian

Frequent Co-Authors

Kamel Khalili
Kamel Khalili Temple University
Jay Rappaport
Jay Rappaport Tulane University
Luis Del Valle
Luis Del Valle Louisiana State University Health Sciences Center New Orleans
Krzysztof Reiss
Krzysztof Reiss Louisiana State University Health Sciences Center New Orleans
Pasquale Ferrante
Pasquale Ferrante University of Milan
Antonio Giordano
Antonio Giordano Temple University
Roger J. Pomerantz
Roger J. Pomerantz ContraFect (United States)
Sergio A. Jimenez
Sergio A. Jimenez Thomas Jefferson University
Susan Morgello
Susan Morgello Icahn School of Medicine at Mount Sinai
John N. Brady
John N. Brady National Institutes of Health

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