D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 79 Citations 21,710 209 World Ranking 1066 National Ranking 563
Medicine D-index 79 Citations 22,039 227 World Ranking 12413 National Ranking 6481

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Virus

Eugene O. Major mostly deals with Progressive multifocal leukoencephalopathy, JC virus, Immunology, Virus and Virology. His Progressive multifocal leukoencephalopathy research is under the purview of Multiple sclerosis. His Multiple sclerosis research incorporates themes from Immune reconstitution inflammatory syndrome and Immunotherapy.

His research integrates issues of Slow virus, Immune system, Pathology, Palatine tonsil and Tandem repeat in his study of JC virus. Eugene O. Major interconnects Antibody and Antigen in the investigation of issues within Virus. The various areas that Eugene O. Major examines in his Virology study include Tumor necrosis factor alpha, BK virus, Cytokine, Tonsil and Bone marrow.

His most cited work include:

  • Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project. (709 citations)
  • Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy (690 citations)
  • Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia (519 citations)

What are the main themes of his work throughout his whole career to date?

Eugene O. Major mainly investigates Virology, JC virus, Progressive multifocal leukoencephalopathy, Immunology and Virus. His work deals with themes such as Cell culture, BK virus, Antigen, Molecular biology and Cell type, which intersect with Virology. His JC virus study deals with Progenitor cell intersecting with Cellular differentiation and Neural stem cell.

His Progressive multifocal leukoencephalopathy research is multidisciplinary, incorporating elements of Demyelinating disease, Leukoencephalopathy and Pathology. The concepts of his Immunology study are interwoven with issues in Disease and Central nervous system. Eugene O. Major has researched Virus in several fields, including In situ hybridization and Polymerase chain reaction.

He most often published in these fields:

  • Virology (44.92%)
  • JC virus (42.37%)
  • Progressive multifocal leukoencephalopathy (38.14%)

What were the highlights of his more recent work (between 2013-2021)?

  • Progressive multifocal leukoencephalopathy (38.14%)
  • JC virus (42.37%)
  • Natalizumab (14.83%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Progressive multifocal leukoencephalopathy, JC virus, Natalizumab, Multiple sclerosis and Virology. His research in Progressive multifocal leukoencephalopathy intersects with topics in Leukoencephalopathy, Primary immunodeficiency, Disease, Intensive care medicine and Pediatrics. Virus covers Eugene O. Major research in JC virus.

His Natalizumab course of study focuses on Dosing and Surgery. His Virology research integrates issues from Antisense oligonucleotides, Oligonucleotide, Lymphocyte and CXCR4. His Immunology research incorporates elements of BK virus and Encephalopathy.

Between 2013 and 2021, his most popular works were:

  • Pembrolizumab Treatment for Progressive Multifocal Leukoencephalopathy (125 citations)
  • Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis (122 citations)
  • Pathogenesis of progressive multifocal leukoencephalopathy and risks associated with treatments for multiple sclerosis: a decade of lessons learned. (87 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Virus

His primary scientific interests are in Progressive multifocal leukoencephalopathy, JC virus, Natalizumab, Virology and Multiple sclerosis. His work carried out in the field of JC virus brings together such families of science as Immune system and Pathology. Eugene O. Major has researched Natalizumab in several fields, including Transcription factor and Gene expression.

His research on Virology focuses in particular on Virus. Eugene O. Major works mostly in the field of Virus, limiting it down to concerns involving Mutation and, occasionally, Cancer research. His Multiple sclerosis study is focused on Immunology in general.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project.

Kenneth R. Carson;Andrew M. Evens;Elizabeth A. Richey;Thomas M. Habermann.
Blood (2009)

979 Citations

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

Tarek A. Yousry;Eugene O. Major;Caroline Ryschkewitsch;Gary Fahle.
The New England Journal of Medicine (2006)

903 Citations

Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain.

E O Major;K Amemiya;C S Tornatore;S A Houff.
Clinical Microbiology Reviews (1992)

760 Citations

Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

Katherine Conant;Alfredo Garzino-Demo;Avindra Nath;Justin C. McArthur.
Proceedings of the National Academy of Sciences of the United States of America (1998)

671 Citations

Progressive Multifocal Leukoencephalopathy in Patients on Immunomodulatory Therapies

Eugene O. Major.
Annual Review of Medicine (2010)

622 Citations

Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid.

Melvyn P. Heyes;Cristian L. Achim;Clayton A. Wiley;Eugene O. Major.
Biochemical Journal (1992)

603 Citations

PML diagnostic criteria: Consensus statement from the AAN neuroinfectious disease section

Joseph R. Berger;Allen J. Aksamit;David B. Clifford;Larry Davis.
Neurology (2013)

595 Citations

Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project

Kenneth R Carson;Daniele Focosi;Eugene O Major;Mario Petrini.
Lancet Oncology (2009)

594 Citations

HIV‐1 infection of subcortical astrocytes in the pediatric central nervous system

Carlo Tornatore;Roma Chandra;Joseph R. Berger;Eugene O. Major.
Neurology (1994)

568 Citations

Establishment of a line of human fetal glial cells that supports JC virus multiplication.

E O Major;A E Miller;P Mourrain;R G Traub.
Proceedings of the National Academy of Sciences of the United States of America (1985)

455 Citations

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