World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
88
Citations
27405
World Ranking
1170
National Ranking
620

Medicine

D-Index
88
Citations
27406
World Ranking
13196
National Ranking
6726

Overview

Eugene O. Major is affiliated with the National Institutes of Health in the United States. Their research primarily spans the field of Medicine with a particular focus on Oncology, Plant Science, Electrical and Electronic Engineering, Pathology and Forensic Medicine, and Molecular Biology.

Their main topics of work include:

  • Polyomavirus and related diseases
  • Plant Virus Research Studies
  • Multiple Sclerosis Research Studies
  • Full-Duplex Wireless Communications
  • Antenna Design and Analysis
  • HIV Research and Treatment
  • Cytomegalovirus and herpesvirus research

Major has contributed to multiple papers covering diverse biomedical and technological subjects. Recent publications include:

  • "BK virus-specific T cells for immunotherapy of progressive multifocal leukoencephalopathy: an open-label, single-cohort pilot study" (2021), published in The Lancet Neurology
  • "Productive HIV infection in astrocytes can be established via a nonclassical mechanism" (2020), published in AIDS
  • "Intranasal anti-caspase-1 therapy preserves myelin and glucose metabolism in a model of progressive multiple sclerosis" (2020), published in Glia
  • "A human-derived 3D brain organoid model to study JC virus infection" (2022), published in Journal of NeuroVirology
  • "Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies" (2022), published in Frontiers in Neurology

Frequent coauthors in Major's work include:

  • Maria Chiara Monaco
  • Irene Cortese
  • Gina Norato
  • Avindra Nath
  • Dragan Maric

Major's research is often published in venues such as:

  • The Lancet Neurology
  • Frontiers in Neurology
  • Neurology Neuroimmunology & Neuroinflammation
  • AIDS
  • Glia

Best Publications

  • Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project.

    Kenneth R. Carson;Andrew M. Evens;Elizabeth A. Richey;Thomas M. Habermann

  • Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

    Tarek A. Yousry;Eugene O. Major;Caroline Ryschkewitsch;Gary Fahle

  • Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain.

    E O Major;K Amemiya;C S Tornatore;S A Houff

  • PML diagnostic criteria: Consensus statement from the AAN neuroinfectious disease section

    Joseph R. Berger;Allen J. Aksamit;David B. Clifford;Larry Davis

  • Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

    Katherine Conant;Alfredo Garzino-Demo;Avindra Nath;Justin C. McArthur

  • Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid.

    M P Heyes;K Saito;S P Markey

  • Progressive Multifocal Leukoencephalopathy in Patients on Immunomodulatory Therapies

    Eugene O. Major

  • Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project

    Kenneth R Carson;Daniele Focosi;Eugene O Major;Mario Petrini

  • Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis

    Brienne A. McKenzie;Manmeet K. Mamik;Leina B. Saito;Roobina Boghozian;Roobina Boghozian

  • HIV‐1 infection of subcortical astrocytes in the pediatric central nervous system

    Carlo Tornatore;Roma Chandra;Joseph R. Berger;Eugene O. Major

  • Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain.

    Michael W. Ferenczy;Leslie J. Marshall;Christian D. S. Nelson;Walter J. Atwood

  • Establishment of a line of human fetal glial cells that supports JC virus multiplication.

    E O Major;A E Miller;P Mourrain;R G Traub

  • Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy.

    Sidney A. Houff;Eugene O. Major;David A. Katz;Conrad V. Kufta

  • Transient Exposure to HIV-1 Tat Protein Results in Cytokine Production in Macrophages and Astrocytes A HIT AND RUN PHENOMENON

    Avindra Nath;Katherine Conant;Peiqin Chen;Catherine Scott

  • Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring

    Ludwig Kappos;David Bates;Gilles Edan;Mefkûre Eraksoy

  • Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein

    N Dyson;R Bernards;S H Friend;L R Gooding

  • JC virus infection of hematopoietic progenitor cells, primary B lymphocytes, and tonsillar stromal cells: implications for viral latency.

    M. C. G. Monaco;W. J. Atwood;M. Gravell;C. S. Tornatore

  • HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes.

    Jonathan M. Weiss;Avindra Nath;Eugene O. Major;Joan W. Berman

  • Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta.

    C Tornatore;A Nath;K Amemiya;E O Major

  • Detection of JC Virus DNA in Human Tonsil Tissue: Evidence for Site of Initial Viral Infection

    Maria Chiara G. Monaco;Peter N. Jensen;Jean Hou;Linda C. Durham

Frequent Co-Authors

Avindra Nath
Avindra Nath National Institutes of Health
David B. Clifford
David B. Clifford Washington University in St. Louis
Joseph R. Berger
Joseph R. Berger University of Pennsylvania
Walter J. Atwood
Walter J. Atwood Brown University
Elliot M. Frohman
Elliot M. Frohman The University of Texas at Austin
Hans H. Hirsch
Hans H. Hirsch University Hospital of Basel
Daniel C. Douek
Daniel C. Douek National Institute of Allergy and Infectious Diseases
Pankaj Seth
Pankaj Seth National Brain Research Centre
Christopher Power
Christopher Power University of Alberta
Keerti V. Shah
Keerti V. Shah Johns Hopkins University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in studying Immunology in the USA, exploring related online degrees can open diverse career pathways. Nursing programs, for instance, often complement immunology knowledge by providing essential clinical skills. Many students begin with foundational programs like online RN programs for non nurses in Florida, which allow career changers to enter the nursing field efficiently.

Accelerated programs are another popular route, designed to fast-track students through nursing education. If time efficiency is a priority, accelerated nursing programs near me can provide flexible options for busy learners.

For advanced practice nurses, transitioning from an FNP (Family Nurse Practitioner) role to specialized acute care is a valuable career upgrade. Detailed guidance is available on making this change through resources like fnp to acnp programs.

To enter these specializations faster, exploring the accelerated FNP programs can help prospective students gain credentials quickly while balancing other commitments.

Best Scientists Citing Eugene O. Major

Trending Scientists

Recently Published Articles