Eugene O. Major mostly deals with Progressive multifocal leukoencephalopathy, JC virus, Immunology, Virus and Virology. His Progressive multifocal leukoencephalopathy research is under the purview of Multiple sclerosis. His Multiple sclerosis research incorporates themes from Immune reconstitution inflammatory syndrome and Immunotherapy.
His research integrates issues of Slow virus, Immune system, Pathology, Palatine tonsil and Tandem repeat in his study of JC virus. Eugene O. Major interconnects Antibody and Antigen in the investigation of issues within Virus. The various areas that Eugene O. Major examines in his Virology study include Tumor necrosis factor alpha, BK virus, Cytokine, Tonsil and Bone marrow.
Eugene O. Major mainly investigates Virology, JC virus, Progressive multifocal leukoencephalopathy, Immunology and Virus. His work deals with themes such as Cell culture, BK virus, Antigen, Molecular biology and Cell type, which intersect with Virology. His JC virus study deals with Progenitor cell intersecting with Cellular differentiation and Neural stem cell.
His Progressive multifocal leukoencephalopathy research is multidisciplinary, incorporating elements of Demyelinating disease, Leukoencephalopathy and Pathology. The concepts of his Immunology study are interwoven with issues in Disease and Central nervous system. Eugene O. Major has researched Virus in several fields, including In situ hybridization and Polymerase chain reaction.
The scientist’s investigation covers issues in Progressive multifocal leukoencephalopathy, JC virus, Natalizumab, Multiple sclerosis and Virology. His research in Progressive multifocal leukoencephalopathy intersects with topics in Leukoencephalopathy, Primary immunodeficiency, Disease, Intensive care medicine and Pediatrics. Virus covers Eugene O. Major research in JC virus.
His Natalizumab course of study focuses on Dosing and Surgery. His Virology research integrates issues from Antisense oligonucleotides, Oligonucleotide, Lymphocyte and CXCR4. His Immunology research incorporates elements of BK virus and Encephalopathy.
His primary scientific interests are in Progressive multifocal leukoencephalopathy, JC virus, Natalizumab, Virology and Multiple sclerosis. His work carried out in the field of JC virus brings together such families of science as Immune system and Pathology. Eugene O. Major has researched Natalizumab in several fields, including Transcription factor and Gene expression.
His research on Virology focuses in particular on Virus. Eugene O. Major works mostly in the field of Virus, limiting it down to concerns involving Mutation and, occasionally, Cancer research. His Multiple sclerosis study is focused on Immunology in general.
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Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project.
Kenneth R. Carson;Andrew M. Evens;Elizabeth A. Richey;Thomas M. Habermann.
Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy
Tarek A. Yousry;Eugene O. Major;Caroline Ryschkewitsch;Gary Fahle.
The New England Journal of Medicine (2006)
Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain.
E O Major;K Amemiya;C S Tornatore;S A Houff.
Clinical Microbiology Reviews (1992)
Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia
Katherine Conant;Alfredo Garzino-Demo;Avindra Nath;Justin C. McArthur.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Progressive Multifocal Leukoencephalopathy in Patients on Immunomodulatory Therapies
Eugene O. Major.
Annual Review of Medicine (2010)
Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid.
Melvyn P. Heyes;Cristian L. Achim;Clayton A. Wiley;Eugene O. Major.
Biochemical Journal (1992)
PML diagnostic criteria: Consensus statement from the AAN neuroinfectious disease section
Joseph R. Berger;Allen J. Aksamit;David B. Clifford;Larry Davis.
Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project
Kenneth R Carson;Daniele Focosi;Eugene O Major;Mario Petrini.
Lancet Oncology (2009)
HIV‐1 infection of subcortical astrocytes in the pediatric central nervous system
Carlo Tornatore;Roma Chandra;Joseph R. Berger;Eugene O. Major.
Establishment of a line of human fetal glial cells that supports JC virus multiplication.
E O Major;A E Miller;P Mourrain;R G Traub.
Proceedings of the National Academy of Sciences of the United States of America (1985)
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