Quinolinic acid, Kynurenine pathway, Microglia, Immunology and Kynurenic acid are his primary areas of study. His Quinolinic acid study combines topics from a wide range of disciplines, such as Internal medicine, Pathogenesis, Endocrinology and Kynurenine. His Kynurenine pathway study combines topics in areas such as Astrocyte, Neuroinflammation, Cell biology, Pharmacology and Indoleamine 2,3-dioxygenase.
Gilles J. Guillemin focuses mostly in the field of Neuroinflammation, narrowing it down to matters related to Neuroprotection and, in some cases, Disease and Neurodegeneration. His biological study spans a wide range of topics, including ABCA7, ABCA8, ATP-binding cassette transporter, Gene expression and Neuroglia. His Kynurenic acid research integrates issues from Multiple sclerosis, Dementia and Kynureninase.
His primary areas of investigation include Kynurenine pathway, Quinolinic acid, Immunology, Biochemistry and Kynurenine. His Kynurenine pathway research includes themes of Kynurenic acid, Bioinformatics, Pathogenesis, Neuroinflammation and Indoleamine 2,3-dioxygenase. His Neuroinflammation research is multidisciplinary, incorporating perspectives in Neurodegeneration and Neuroscience.
The various areas that Gilles J. Guillemin examines in his Quinolinic acid study include Microglia, Neuroprotection, Pharmacology, Excitotoxicity and Cell biology. His studies in Cell biology integrate themes in fields like NMDA receptor and Molecular biology. The study incorporates disciplines such as Metabolite, Internal medicine and Endocrinology in addition to Kynurenine.
His primary scientific interests are in Kynurenine pathway, Kynurenine, Pharmacology, Cell biology and Neuroprotection. His Kynurenine pathway research includes elements of Biomarker, Neuroinflammation, Kynurenic acid and Bioinformatics. The concepts of his Kynurenine study are interwoven with issues in Endocrinology, Inflammation, Internal medicine, Pathogenesis and Quinolinic acid.
Gilles J. Guillemin carries out multidisciplinary research, doing studies in Quinolinic acid and Population. His Pharmacology research includes themes of Viability assay, Memantine, Signal transduction and Chronic pain. His research in Neuroprotection intersects with topics in Oxidative stress, Neurotoxicity, Sphingosine, Sphingosine-1-phosphate and Neurodegeneration.
Gilles J. Guillemin mostly deals with Kynurenine, Kynurenine pathway, Internal medicine, Neuroprotection and Neurotoxicity. His Kynurenine research integrates issues from Cytokine, Indoleamine 2,3-dioxygenase, Quinolinic acid, Cell biology and Candidate gene. Gilles J. Guillemin combines subjects such as SH-SY5Y, Transcriptome and NAD+ kinase with his study of Quinolinic acid.
His work carried out in the field of Kynurenine pathway brings together such families of science as Kynurenic acid, Case-control study, Neopterin, Serotonin and Alzheimer's disease. While the research belongs to areas of Internal medicine, Gilles J. Guillemin spends his time largely on the problem of Endocrinology, intersecting his research to questions surrounding Pathogenesis. His Neuroprotection research is classified as research in Pharmacology.
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An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
Christiane A. Opitz;Ulrike M. Litzenburger;Ulrike M. Litzenburger;Felix Sahm;Martina Ott.
Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification
Gilles J. Guillemin;Gilles J. Guillemin;Bruce J. Brew.
Journal of Leukocyte Biology (2004)
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?
Johann Steiner;Johann Steiner;Martin Walter;Tomasz Gos;Tomasz Gos;Gilles J Guillemin.
Journal of Neuroinflammation (2011)
Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats
Nady Braidy;Gilles J. Guillemin;Hussein Mansour;Tailoi Chan-Ling.
PLOS ONE (2011)
Kynurenine Pathway Metabolites in Humans: Disease and Healthy States:
Yiquan Chen;Gilles J. Guillemin.
International Journal of Tryptophan Research (2009)
Aryl hydrocarbon receptor control of a disease tolerance defence pathway
Alban Bessede;Alban Bessede;Marco Gargaro;Maria T. Pallotta;Davide Matino.
Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection
Gilles J. Guillemin;Stephen J. Kerr;George A. Smythe;Danielle G. Smith.
Journal of Neurochemistry (2001)
Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons.
Gilles J. Guillemin;Gilles J. Guillemin;George Smythe;Osamu Takikawa;Bruce J. Brew;Bruce J. Brew.
Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.
Hassina Massudi;Ross Grant;Ross Grant;Nady Braidy;Jade Guest;Jade Guest.
PLOS ONE (2012)
Quinolinic acid, the inescapable neurotoxin.
Gilles J. Guillemin;Gilles J. Guillemin.
FEBS Journal (2012)
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