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Francesca Fallarino

Francesca Fallarino

D-Index & Metrics

Immunology

D-Index
78
Citations
28986
World Ranking
1724
National Ranking
67

Overview

Francesca Fallarino is affiliated with the University of Perugia in Italy and has contributed extensively to research in Medicine as well as Biochemistry, Genetics, and Molecular Biology. Their scholarly output includes publications across several interrelated subfields such as Immunology, Molecular Biology, Biological Psychiatry, Oncology, and Physiology.

Their research focuses on topics including Tryptophan and brain disorders, Immune Cell Function and Interaction, Extracellular vesicles in disease, Immunotherapy and Immune Responses, Stress Responses and Cortisol, Immune cells in cancer, and Gut microbiota and health.

Frequent coauthors working alongside Francesca Fallarino include Marco Gargaro, Giorgia Manni, Paolo Puccetti, Giulia Scalisi, and Giada Mondanelli.

Publications have appeared primarily in venues such as Frontiers in Immunology, International Journal of Molecular Sciences, eLife, Nature Communications, and Journal of Biological Chemistry.

Representative recent papers authored or co-authored by Francesca Fallarino include:

  • Is Acetylsalicylic Acid a Safe and Potentially Useful Choice for Adult Patients with COVID-19? (2020) in Drugs
  • Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism (2021) in eLife
  • Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication (2022) in Immunity
  • Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation (2020) in Proceedings of the National Academy of Sciences
  • 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine (2021) in Nature Communications

Best Publications

  • Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

    Teresa Zelante;Rossana G. Iannitti;Cristina Cunha;Antonella De Luca

  • Modulation of tryptophan catabolism by regulatory T cells.

    Francesca Fallarino;Ursula Grohmann;Kwang Woo Hwang;Ciriana Orabona

  • CTLA-4-Ig regulates tryptophan catabolism in vivo.

    Ursula Grohmann;Ciriana Orabona;Francesca Fallarino;Carmine Vacca

  • Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

    Michael Platten;Michael Platten;Ellen A A Nollen;Ute F Röhrig;Francesca Fallarino

  • The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells

    Francesca Fallarino;Ursula Grohmann;Sylvaine You;Barbara C. McGrath

  • T cell apoptosis by tryptophan catabolism.

    Francesca Fallarino;Ursula Grohmann;Carmine Vacca;Roberta Bianchi

  • BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.

    Norihiko Watanabe;Norihiko Watanabe;Maya Gavrieli;John R Sedy;Jianfei Yang;Jianfei Yang

  • Tolerance, DCs and tryptophan: much ado about IDO

    Ursula Grohmann;Francesca Fallarino;Paolo Puccetti

  • Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

    Maria T Pallotta;Ciriana Orabona;Claudia Volpi;Carmine Vacca

  • Aryl hydrocarbon receptor control of a disease tolerance defence pathway

    Alban Bessede;Alban Bessede;Marco Gargaro;Maria T. Pallotta;Davide Matino

  • Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

    Luigina Romani;Francesca Fallarino;Antonella De Luca;Claudia Montagnoli

  • Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction

    Gianluca Matteoli;Elisa Mazzini;Iliyan D Iliev;Erika Mileti

  • CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86

    Ciriana Orabona;Ursula Grohmann;Maria Laura Belladonna;Francesca Fallarino

  • IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis

    Yaping Yan;Guang Xian Zhang;Bruno Gran;Francesca Fallarino

  • Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy.

    Ursula Grohmann;Claudia Volpi;Francesca Fallarino;Silvia Bozza

  • IL-23 and IL-12 Have Overlapping, but Distinct, Effects on Murine Dendritic Cells

    Maria Laura Belladonna;Jean-Christophe Renauld;Roberta Bianchi;Carmine Vacca

  • A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells.

    Giada Mondanelli;Roberta Bianchi;Maria Teresa Pallotta;Ciriana Orabona

  • IL-22 defines a novel immune pathway of antifungal resistance

    A. De Luca;T. Zelante;C. D'Angelo;S. Zagarella

  • Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells

    Francesca Fallarino;Carmine Vacca;Ciriana Orabona;Maria L. Belladonna

  • TLRs govern neutrophil activity in aspergillosis.

    Silvia Bellocchio;Silvia Moretti;Katia Perruccio;Francesca Fallarino

  • Murine Plasmacytoid Dendritic Cells Initiate the Immunosuppressive Pathway of Tryptophan Catabolism in Response to CD200 Receptor Engagement

    Francesca Fallarino;Carine Asselin-Paturel;Carmine Vacca;Roberta Bianchi

Frequent Co-Authors

Paolo Puccetti
Paolo Puccetti University of Perugia
Carmine Vacca
Carmine Vacca University of Perugia
Ursula Grohmann
Ursula Grohmann University of Perugia
Ciriana Orabona
Ciriana Orabona University of Perugia
Roberta Bianchi
Roberta Bianchi University of Perugia
Maria C. Fioretti
Maria C. Fioretti University of Perugia
Luigina Romani
Luigina Romani University of Perugia
Teresa Zelante
Teresa Zelante University of Perugia
Silvia Bozza
Silvia Bozza University of Perugia
Thomas F. Gajewski
Thomas F. Gajewski University of Chicago

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