2016 - Member of the National Academy of Sciences
The scientist’s investigation covers issues in Immunology, Cell biology, Interleukin 12, Cytotoxic T cell and Cellular differentiation. Immune system, Antigen, Cytokine, Dendritic cell and T lymphocyte are the core of his Immunology study. His Cell biology research incorporates elements of T cell, IL-2 receptor, Transcription and Receptor.
His study in Interleukin 12 is interdisciplinary in nature, drawing from both STAT4, Lipopolysaccharide, Bacteria, Molecular biology and Interleukin 4. His Cytotoxic T cell research includes elements of Priming and T helper cell. The various areas that he examines in his Cellular differentiation study include Lineage, Intestinal mucosa, Stem cell and BATF.
His scientific interests lie mostly in Cell biology, Immunology, T cell, Molecular biology and Antigen. Kenneth M. Murphy has researched Cell biology in several fields, including Interleukin 12, Dendritic cell, Transcription factor and Cellular differentiation. His Interleukin 12 research is multidisciplinary, incorporating perspectives in Phenotype, STAT4 and Interferon gamma.
His studies in Immune system, T lymphocyte, Cytokine, Antigen-presenting cell and CD8 are all subfields of Immunology research. His research in T cell intersects with topics in Cytotoxic T cell and Priming. Kenneth M. Murphy interconnects Antigen presentation and T-cell receptor in the investigation of issues within Antigen.
Kenneth M. Murphy focuses on Cell biology, Dendritic cell, Antigen, Immune system and T cell. His Cell biology research includes elements of Transcription factor, Cell, Receptor and T-cell receptor. His Dendritic cell research integrates issues from Cytokine, Cell type, Histiocyte, Regulatory T cell and Neuroscience.
His Antigen study combines topics in areas such as Genetic model and Transgene. His Immune system study is related to the wider topic of Immunology. His study in Immunology is interdisciplinary in nature, drawing from both Gene and Disease.
Kenneth M. Murphy focuses on Cell biology, Dendritic cell, Antigen, Progenitor cell and Cytokine. His work in Cell biology covers topics such as T cell which are related to areas like Priming. The study incorporates disciplines such as Lung cancer and Cancer research in addition to Dendritic cell.
Kenneth M. Murphy focuses mostly in the field of Antigen, narrowing it down to topics relating to Genetic model and, in certain cases, B cell, Humoral immunity, MHC class I, Germinal center and Function. His biological study spans a wide range of topics, including CXCL2, Inflammation, CD11c, Green fluorescent protein and Motility. His research on Immune system concerns the broader Immunology.
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Dendritic cell regulation of TH1-TH2 development.
Muriel Moser;Kenneth M. Murphy.
Nature Immunology (2000)
Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells.
Susanne J. Szabo;Anand S. Dighe;Ueli Gubler;Kenneth M. Murphy.
Journal of Experimental Medicine (1997)
Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells
Mercedes B. Fuertes;Aalok K. Kacha;Justin Kline;Seng Ryong Woo.
Journal of Experimental Medicine (2011)
Guidelines for the use of flow cytometry and cell sorting in immunological studies
Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis.
European Journal of Immunology (2017)
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
Mark S. Diamond;Michelle Kinder;Hirokazu Matsushita;Mona Mashayekhi.
Journal of Experimental Medicine (2011)
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4.
N. G. Jacobson;S. J. Szabo;R. M. Weber-Nordt;Zhong Zhong.
Journal of Experimental Medicine (1995)
Signaling and Transcription in T Helper Development
Kenneth M. Murphy;Wenjun Ouyang;J. David Farrar;Jianfei Yang.
Annual Review of Immunology (2000)
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells
Brian T. Edelson;Wumesh Kc;Richard Juang;Masako Kohyama.
Journal of Experimental Medicine (2010)
B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator.
John R Sedy;Maya Gavrieli;Karen G Potter;Michelle A Hurchla.
Nature Immunology (2005)
Regulation of interleukin 12 p40 expression through an NF-kappa B half-site.
T L Murphy;M G Cleveland;P Kulesza;J Magram.
Molecular and Cellular Biology (1995)
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