World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
22133
World Ranking
17395
National Ranking
7148

Overview

Chyi-Song Hsieh is affiliated with Washington University in St. Louis in the United States. Their research spans multiple areas primarily within medicine and immunology and microbiology, with notable contributions in immunology, oncology, dermatology, infectious diseases, and physiology.

The scientist's work emphasizes several main topics, including:

  • Immune Cell Function and Interaction
  • IL-33, ST2, and ILC Pathways
  • T-cell and B-cell Immunology
  • Dermatology and Skin Diseases
  • Lymphatic System and Diseases
  • Asthma and Respiratory Diseases
  • Urticaria and Related Conditions

Frequent coauthors collaborating with Chyi-Song Hsieh include:

  • Jiani Chai (10 publications)
  • Rodney D. Newberry (8 publications)
  • Anna M. Trier (7 publications)
  • Madison R. Mack (7 publications)
  • Aaron Ver Heul (7 publications)

Hsieh's publications commonly appear in the following venues:

  • The Journal of Immunology (7 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • eLife (3 publications)
  • Immunity (2 publications)
  • Cell Reports (2 publications)

Notable recent papers authored or co-authored by Chyi-Song Hsieh include:

  • "A basophil-neuronal axis promotes itch," 2021, Cell
  • "Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor," 2021, Immunity
  • "A Potential Role for Stress-Induced Microbial Alterations in IgA-Associated Irritable Bowel Syndrome with Diarrhea," 2020, Cell Reports Medicine
  • "Commensal Cryptosporidium colonization elicits a cDC1-dependent Th1 response that promotes intestinal homeostasis and limits other infections," 2021, Immunity
  • "Antigen-specific depletion of CD4 + T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity," 2022, Science Immunology

Best Publications

  • Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

    Chyi Song Hsieh;Steven E. Macatonia;Catherine S. Tripp;Stanley F. Wolf

  • Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

    S. E. Macatonia;N. A. Hosken;M. Litton;P. Vieira

  • Peripheral education of the immune system by colonic commensal microbiota

    Stephanie K. Lathrop;Seth M. Bloom;Sindhuja M. Rao;Katherine Nutsch

  • Recognition of the Peripheral Self by Naturally Arising CD25+ CD4+ T Cell Receptors

    Chyi-Song Hsieh;Yuqiong Liang;Aaron J. Tyznik;Steven G. Self

  • Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch

    Landon K. Oetjen;Madison R. Mack;Jing Feng;Timothy M. Whelan

  • Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system.

    Chyi-Song Hsieh;Amy B. Heimberger;Jennifer S. Gold;Anne O'Garra

  • Lactobacillus reuteri induces gut intraepithelial CD4+CD8αα+ T cells.

    Luisa Cervantes-Barragan;Jiani N. Chai;Ma Diarey Tianero;Blanda Di Luccia

  • A two-step process for thymic regulatory T cell development

    Chan-Wang Joaquim Lio;Chyi-Song Hsieh

  • An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires.

    Chyi-Song Hsieh;Chyi-Song Hsieh;Ye Zheng;Yuqiong Liang;Jason D Fontenot

  • T CELL GENETIC BACKGROUND DETERMINES DEFAULT T HELPER PHENOTYPE DEVELOPMENT IN VITRO

    Chyi-Song Hsieh;Steven E. Macatonia;Anne O'Garra;Kenneth M. Murphy

  • Selection of regulatory T cells in the thymus

    Chyi-Song Hsieh;Hyang-Mi Lee;Chan-Wang J. Lio;Chan-Wang J. Lio

  • B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation.

    Erin E. Murphy;Geronimo Terres;Steven E. Macatonia;Chyi-Song Hsieh

  • Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

    Matthew A. Burchill;Jianying Yang;Kieng B. Vang;James J. Moon

  • Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-γ production is IFN-γ-dependent

    Steven E. Macatonia;Chyi-Song Hsieh;Kenneth M. Murphy;Anne O'Garra

  • Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer

    Marcus C. B. Tan;Peter S. Goedegebuure;Brian A. Belt;Brian Flaherty

  • Genetic Susceptibility to Leishmania: IL-12 Responsiveness in TH1 Cell Development

    Mehmet L. Güler;James D. Gorham;Chyi Song Hsieh;Aaron J. Mackey

  • Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy

    Andrew L. Kau;Joseph D. Planer;Jie Liu;Sindhuja Rao

  • Intraclonal competition limits the fate determination of regulatory T cells in the thymus

    Jhoanne L Bautista;Chan-Wang J Lio;Stephanie K Lathrop;Katherine Forbush

  • Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth

    Matthew R. Porembka;Jonathan B. Mitchem;Brian A. Belt;Chyi Song Hsieh

  • Distinct Contributions of Aire and Antigen-Presenting-Cell Subsets to the Generation of Self-Tolerance in the Thymus

    Justin S.A. Perry;Chan Wang J. Lio;Andrew L. Kau;Katherine Nutsch

Frequent Co-Authors

Kenneth M. Murphy
Kenneth M. Murphy Washington University in St. Louis
Anne O'Garra
Anne O'Garra The Francis Crick Institute
Alexander Y. Rudensky
Alexander Y. Rudensky Memorial Sloan Kettering Cancer Center
Rodney D. Newberry
Rodney D. Newberry Washington University in St. Louis
Brian S. Kim
Brian S. Kim Icahn School of Medicine at Mount Sinai
Thaddeus S. Stappenbeck
Thaddeus S. Stappenbeck Washington University in St. Louis
Jeffrey I. Gordon
Jeffrey I. Gordon Washington University in St. Louis
Daniel A. Peterson
Daniel A. Peterson Rosalind Franklin University of Medicine and Science
Marco Colonna
Marco Colonna Washington University in St. Louis
Mark J. Miller
Mark J. Miller Washington University in St. Louis

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