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Immunology

D-Index
63
Citations
23037
World Ranking
2978
National Ranking
199

Overview

Jochen Huehn is affiliated with the Helmholtz Centre for Infection Research in Germany and works primarily in the field of Immunology and Microbiology. Their research contributions comprise 119 publications focused on various aspects of immune system functionality and related biological processes.

Their main subfields of study include:

  • Immunology
  • Molecular Biology
  • Epidemiology
  • Infectious Diseases
  • Nutrition and Dietetics

Huehn's research topics cover diverse areas within immunological science, such as:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • IL-33, ST2, and ILC Pathways
  • Immune responses and vaccinations
  • Gut microbiota and health
  • Immune cells in cancer

The scientist has published extensively in notable venues, with multiple publications in:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Journal of Immunology
  • Immunity
  • Cellular and Molecular Immunology

Several recent papers authored or co-authored by Huehn include:

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition), 2021, European Journal of Immunology
  • Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells, 2021, Immunity
  • Salt generates antiinflammatory Th17 cells but amplifies pathogenicity in proinflammatory cytokine microenvironments, 2020, Journal of Clinical Investigation
  • Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes, 2022, Immunity
  • The dark side of Tregs during aging, 2022, Frontiers in Immunology

Huehn has collaborated frequently with a group of co-authors, including:

  • Stefan Floess
  • Michael Beckstette
  • Mangge Zou
  • Carolin Wiechers
  • Joern Pezoldt

Best Publications

  • Epigenetic Control of the foxp3 Locus in Regulatory T Cells

    Stefan Floess;Jennifer Freyer;Christiane Siewert;Udo Baron

  • Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease.

    Katharina Lahl;Christoph Loddenkemper;Cathy Drouin;Jennifer Freyer

  • De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

    Luciana Berod;Christin Friedrich;Amrita Nandan;Jenny Freitag

  • DNA methylation controls Foxp3 gene expression.

    Julia K. Polansky;Karsten Kretschmer;Karsten Kretschmer;Jennifer Freyer;Stefan Floess

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development

    Naganari Ohkura;Naganari Ohkura;Masahide Hamaguchi;Masahide Hamaguchi;Hiromasa Morikawa;Hiromasa Morikawa;Kyoko Sugimura

  • DNA Demethylation in the Human FOXP3 Locus Discriminates Regulatory T Cells From Activated FOXP3(+) Conventional T Cells

    Udo Baron;Stefan Floess;Georg Wieczorek;Katrin Baumann

  • Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

    Jochen Huehn;Kerstin Siegmund;Joachim C.U. Lehmann;Christiane Siewert

  • Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

    Jonathan M. Weiss;Angelina M. Bilate;Michael Gobert;Yi Ding

  • Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?

    Jochen Huehn;Julia K. Polansky;Alf Hamann

  • The invasin D protein from Yersinia pseudotuberculosis selectively binds the Fab region of host antibodies and affects colonization of the intestine

    Pooja Sadana;Rebecca Geyer;Joern Pezoldt;Saskia Helmsing

  • Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

    Takahisa Miyao;Stefan Floess;Ruka Setoguchi;Hervé Luche

  • Expression of the integrin αEβ7 identifies unique subsets of CD25+ as well as CD25− regulatory T cells

    Joachim Lehmann;Jochen Huehn;Maurus de la Rosa;Frank Maszyna

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

    Unknown

  • Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells.

    Bianca Schaub;Jing Liu;Sabine Höppler;Isolde Schleich

  • Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation

    Dorota Klysz;Xuguang Tai;Philippe A. Robert;Marco Craveiro

  • Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation.

    B-H Yang;S Hagemann;P Mamareli;U Lauer

  • Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation.

    Petra Hoffmann;Tina J. Boeld;Ruediger Eder;Jochen Huehn

  • Quantitative DNA Methylation Analysis of FOXP3 as a New Method for Counting Regulatory T Cells in Peripheral Blood and Solid Tissue

    Georg Wieczorek;Anne Asemissen;Fabian Model;Ivana Turbachova

  • Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo.

    Kerstin Siegmund;Markus Feuerer;Christiane Siewert;Saeed Ghani

  • Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma.

    Katjana Klages;Christian T. Mayer;Katharina Lahl;Christoph Loddenkemper

Frequent Co-Authors

Tim Sparwasser
Tim Sparwasser Johannes Gutenberg University of Mainz
Christoph Loddenkemper
Christoph Loddenkemper Charité - University Medicine Berlin
Immo Prinz
Immo Prinz Hannover Medical School
Michael Meyer-Hermann
Michael Meyer-Hermann Technische Universität Braunschweig
Robert Geffers
Robert Geffers Helmholtz Centre for Infection Research
Christine S. Falk
Christine S. Falk Hannover Medical School
Shimon Sakaguchi
Shimon Sakaguchi Osaka University
Petra Dersch
Petra Dersch University of Münster
Wolfgang Baumgärtner
Wolfgang Baumgärtner University of Veterinary Medicine Vienna
Alf Hamann
Alf Hamann Charité - University Medicine Berlin

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