World's Best Scientists 2026 revealed!

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Immunology

D-Index
83
Citations
20653
World Ranking
1470
National Ranking
12

Medicine

D-Index
83
Citations
21100
World Ranking
15775
National Ranking
181

Overview

Song Guo Zheng is affiliated with Shanghai Jiao Tong University in China and has contributed extensively to research in medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their work is particularly concentrated in immunology, molecular biology, genetics, oncology, and rheumatology.

The main topics addressed in their research include:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Mesenchymal stem cell research
  • Immunotherapy and Immune Responses
  • Extracellular vesicles in disease
  • Systemic Lupus Erythematosus Research
  • Immune cells in cancer

Song Guo Zheng's notable recent papers encompass the following:

  • Inosine is an alternative carbon source for CD8+-T-cell function under glucose restriction, 2020, published in Nature Metabolism
  • Small extracellular vesicles derived from human mesenchymal stromal cells prevent group 2 innate lymphoid cell-dominant allergic airway inflammation through delivery of miR-146a-5p, 2020, published in Journal of Extracellular Vesicles
  • An updated advance of autoantibodies in autoimmune diseases, 2020, published in Autoimmunity Reviews
  • Immunomodulatory Function of Vitamin D and Its Role in Autoimmune Thyroid Disease, 2021, published in Frontiers in Immunology
  • Mesenchymal Stem Cell-Derived Exosomes: A Promising Biological Tool in Nanomedicine, 2021, published in Frontiers in Pharmacology

Frequent co-authors collaborating with Song Guo Zheng include:

  • Junlong Dang
  • Joseph A. Bellanti
  • Julie Wang
  • Donglan Zeng
  • Nancy J. Olsen

The scientist has published multiple articles in key academic venues such as:

  • Frontiers in Immunology
  • SSRN Electronic Journal
  • arXiv (Cornell University)
  • Autoimmunity Reviews
  • Journal of Autoimmunity

The bulk of Song Guo Zheng's work spans 133 publications in medicine and over 80 each in biochemistry, genetics, molecular biology, immunology, and microbiology. Their contribution to subfields is most prominent in immunology with 81 publications, followed by molecular biology and genetics.

Best Publications

  • Natural and Induced CD4+CD25+ Cells Educate CD4+CD25− Cells to Develop Suppressive Activity: The Role of IL-2, TGF-β, and IL-10

    Song Guo Zheng;Ju Hua Wang;J. Dixon Gray;Harold Soucier

  • IL-2 Is Essential for TGF-β to Convert Naive CD4+CD25− Cells to CD25+Foxp3+ Regulatory T Cells and for Expansion of These Cells

    Song Guo Zheng;Juhua Wang;Pu Wang;J. Dixon Gray

  • Role of Vitamin A in the Immune System

    Zhiyi Huang;Yu Liu;Guangying Qi;David Brand

  • Generation Ex Vivo of TGF-β-Producing Regulatory T Cells from CD4+CD25− Precursors

    Song Guo Zheng;J. Dixon Gray;Kazuo Ohtsuka;Satoshi Yamagiwa

  • TGF-β Requires CTLA-4 Early after T Cell Activation to Induce FoxP3 and Generate Adaptive CD4+CD25+ Regulatory Cells

    Song Guo Zheng;Ju Hua Wang;William Stohl;Kyoung Soo Kim

  • Vitamin D and Chronic Diseases

    Hanmin Wang;Weiwen Chen;Dongqing Li;Xiaoe Yin

  • Natural and TGF-β–induced Foxp3+CD4+ CD25+ regulatory T cells are not mirror images of each other

    David A. Horwitz;Song Guo Zheng;J. Dixon Gray

  • Cutting Edge: Foxp3+CD4+CD25+ Regulatory T Cells Induced by IL-2 and TGF-β Are Resistant to Th17 Conversion by IL-6

    Song Guo Zheng;Juhua Wang;David A. Horwitz

  • Role of TNF-TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications

    Sujuan Yang;Julie Wang;David Douglass Brand;Song Guo Zheng

  • The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3

    Zuojia Chen;Joseph Barbi;Shurui Bu;Shurui Bu;Huang Yu Yang;Huang Yu Yang

  • Hall of Fame among Pro-inflammatory Cytokines: Interleukin-6 Gene and Its Transcriptional Regulation Mechanisms.

    Yang Luo;Yang Luo;Song Guo Zheng;Song Guo Zheng

  • Inosine is an alternative carbon source for CD8+-T-cell function under glucose restriction

    Tingting Wang;J. N. Rashida Gnanaprakasam;Xuyong Chen;Siwen Kang

  • The role of the combination of IL-2 and TGF-β or IL-10 in the generation and function of CD4+ CD25+ and CD8+regulatory T cell subsets

    David A. Horwitz;Song Guo Zheng;J. Dixon Gray

  • CD4+ and CD8+ Regulatory T Cells Generated Ex Vivo with IL-2 and TGF-β Suppress a Stimulatory Graft-versus-Host Disease with a Lupus-Like Syndrome

    Song Guo Zheng;Ju Hua Wang;Michael N. Koss;Francisco Quismorio

  • Cutting Edge: All-Trans Retinoic Acid Sustains the Stability and Function of Natural Regulatory T Cells in an Inflammatory Milieu

    Xiaohui Zhou;Ning Kong;Ning Kong;Julie Wang;Huiming Fan

  • Adoptive Transfer of Human Gingiva‐Derived Mesenchymal Stem Cells Ameliorates Collagen‐Induced Arthritis via Suppression of Th1 and Th17 Cells and Enhancement of Regulatory T Cell Differentiation

    Maogen Chen;Wenru Su;Xiaohong Lin;Zhiyong Guo

  • Critical role of IL-2 and TGF-β in generation, function and stabilization of Foxp3+CD4+ Treg

    David A. Horwitz;Song Guo Zheng;Juhua Wang;J. Dixon Gray

  • Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

    Ling Lu;Ling Lu;Qin Lan;Qin Lan;Zhiyuan Li;Xiaohui Zhou;Xiaohui Zhou

  • Human CD39hi regulatory T cells present stronger stability and function under inflammatory conditions.

    Jian Gu;Xuhao Ni;Xiongxiong Pan;Hao Lu

  • Small extracellular vesicles derived from human mesenchymal stromal cells prevent group 2 innate lymphoid cell-dominant allergic airway inflammation through delivery of miR-146a-5p.

    Shu-Bin Fang;Hong-Yu Zhang;Cong Wang;Bi-Xin He

  • Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells

    Ling Lu;Julie Wang;Feng Zhang;Yang Chai

  • Characterization of Protective Human CD4+CD25+ FOXP3+ Regulatory T Cells Generated with IL-2, TGF-β and Retinoic Acid

    Ling Lu;Xiaohui Zhou;Julie Wang;Song Guo Zheng

Frequent Co-Authors

David D. Brand
David D. Brand University of Tennessee Health Science Center
David A. Horwitz
David A. Horwitz University of Southern California
Nancy J. Olsen
Nancy J. Olsen Penn State Milton S. Hershey Medical Center
Joseph A. Bellanti
Joseph A. Bellanti Georgetown University
Bernhard Ryffel
Bernhard Ryffel University of Orléans
Wei Shi
Wei Shi University of Southern California
Bin Li
Bin Li Shanghai Jiao Tong University
Valérie F. J. Quesniaux
Valérie F. J. Quesniaux University of Orléans
William Stohl
William Stohl University of Southern California
Avery August
Avery August Cornell University

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