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Immunology

D-Index
51
Citations
10873
World Ranking
4134
National Ranking
1886

Overview

David D. Brand is affiliated with the University of Tennessee Health Science Center in the United States. Their research primarily falls within the broad field of Medicine, with a focus on specialized subfields including Rheumatology, Surgery, Immunology, Molecular Biology, and Immunology and Allergy.

The scientist's work covers several main topics related to disease mechanisms and therapeutic approaches. These include:

  • Osteoarthritis Treatment and Mechanisms
  • Cell Adhesion Molecules Research
  • Monoclonal and Polyclonal Antibodies Research
  • Rheumatoid Arthritis Research and Therapies
  • Knee injuries and reconstruction techniques
  • Cancer-related molecular mechanisms research
  • Inflammasome and immune disorders

The publication record features contributions to various journals, with multiple papers appearing in the following venues:

  • Journal of Biological Chemistry
  • Frontiers in Immunology
  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE

Selected recent papers include:

  • "Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis," 2023, Redox Biology
  • "Leukocyte-associated immunoglobulin-like receptor 1 inhibits T-cell signaling by decreasing protein phosphorylation in the T-cell signaling pathway," 2020, Journal of Biological Chemistry
  • "Development of Tri-Layered Biomimetic Atelocollagen Scaffolds with Interfaces for Osteochondral Tissue Engineering," 2022, Advanced Healthcare Materials
  • "Infusion of GMSCs relieves autoimmune arthritis by suppressing the externalization of neutrophil extracellular traps via PGE2-PKA-ERK axis," 2023, Journal of Advanced Research
  • "Comparison of Phenotypic Characteristics and Prognosis Between Black and White Patients in a Tertiary ALS Clinic," 2020, Neurology

David D. Brand has collaborated frequently with several co-authors, reflecting interdisciplinary and collaborative research engagements. Frequent co-authors include:

  • Linda K. Myers
  • Edward F. Rosloniec
  • Karen A. Hasty
  • Song Guo Zheng
  • John Stuart

Best Publications

  • Collagen-induced arthritis

    David D Brand;David D Brand;Kary A Latham;Kary A Latham;Edward F Rosloniec;Edward F Rosloniec

  • Role of Vitamin A in the Immune System

    Zhiyi Huang;Yu Liu;Guangying Qi;David Brand

  • IL-17–dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants

    William J. Burlingham;Robert B. Love;Robert B. Love;Ewa Jankowska-Gan;Lynn D. Haynes

  • Role of TNF-TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications

    Sujuan Yang;Julie Wang;David Douglass Brand;Song Guo Zheng

  • Immunopathogenesis of collagen arthritis.

    David D. Brand;Andrew H. Kang;Andrew H. Kang;Edward F. Rosloniec;Edward F. Rosloniec

  • An HLA-DR1 Transgene Confers Susceptibility to Collagen-induced Arthritis Elicited with Human Type II Collagen

    Edward F. Rosloniec;David D. Brand;Linda K. Myers;Karen B. Whittington

  • Cutting Edge: All-Trans Retinoic Acid Sustains the Stability and Function of Natural Regulatory T Cells in an Inflammatory Milieu

    Xiaohui Zhou;Ning Kong;Ning Kong;Julie Wang;Huiming Fan

  • Adoptive Transfer of Human Gingiva‐Derived Mesenchymal Stem Cells Ameliorates Collagen‐Induced Arthritis via Suppression of Th1 and Th17 Cells and Enhancement of Regulatory T Cell Differentiation

    Maogen Chen;Wenru Su;Xiaohong Lin;Zhiyong Guo

  • Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

    Ling Lu;Ling Lu;Qin Lan;Qin Lan;Zhiyuan Li;Xiaohui Zhou;Xiaohui Zhou

  • Cleavage of denatured natural collagen type II by neutrophil gelatinase B reveals enzyme specificity, post-translational modifications in the substrate, and the formation of remnant epitopes in rheumatoid arthritis

    Philippe Van den Steen;Paul Proost;Bernard Grillet;David D Brand

  • Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells

    Ling Lu;Julie Wang;Feng Zhang;Yang Chai

  • Anti-type V collagen lymphocytes that express IL-17 and IL-23 induce rejection pathology in fresh and well-healed lung transplants.

    S. Yoshida;A. Haque;T. Mizobuchi;T. Iwata

  • Collagen-induced arthritis.

    Edward F. Rosloniec;Michael Cremer;Andrew H. Kang;Linda K. Myers

  • Advances in distinguishing natural from induced Foxp3+ regulatory T cells

    Xiaohong Lin;Maogen Chen;Maogen Chen;Ya Liu;Zhiyong Guo

  • Induction of Autoimmune Arthritis in HLA-DR4 (DRB1*0401) Transgenic Mice by Immunization with Human and Bovine Type II Collagen

    Edward F. Rosloniec;David D. Brand;Linda K. Myers;Yukio Esaki

  • Antigen-specific transforming growth factor β–induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance

    Ning Kong;Qin Lan;Qin Lan;Maogen Chen;Julie Wang

  • Targeting IL-2: an unexpected effect in treating immunological diseases.

    Congxiu Ye;David Brand;Song Guo Zheng;Song Guo Zheng

  • Porphyromonas gingivalis oral infection exacerbates the development and severity of collagen-induced arthritis

    Julie Teresa Marchesan;Elizabeth Ann Gerow;Riley Schaff;Andrei Dan Taut

  • All-trans retinoic acid promotes TGF-β-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus.

    Ling Lu;Jilin Ma;Zhiyuan Li;Qin Lan;Qin Lan

  • Relevance of Posttranslational Modifications for the Arthritogenicity of Type II Collagen

    Linda K. Myers;Johanna Myllyharju;Minna Nokelainen;David D. Brand;David D. Brand

  • Role of Smad and non-Smad Signals in the Development of Th17 and Regulatory T Cells

    Song Guo Zheng;Ling Lu;Julie Wang;Feng Zhang

Frequent Co-Authors

Song Guo Zheng
Song Guo Zheng Shanghai Jiao Tong University
John M. Stuart
John M. Stuart University of Tennessee Health Science Center
Andrew H. Kang
Andrew H. Kang University of Tennessee Health Science Center
David A. Horwitz
David A. Horwitz University of Southern California
Bernhard Ryffel
Bernhard Ryffel University of Orléans
Wei Shi
Wei Shi University of Southern California
Karen A. Hasty
Karen A. Hasty University of Tennessee Health Science Center
Oscar W. Cummings
Oscar W. Cummings Indiana University
Bin Li
Bin Li Shanghai Jiao Tong University
Arnold E. Postlethwaite
Arnold E. Postlethwaite University of Tennessee Health Science Center

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