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Rikard Holmdahl

Rikard Holmdahl

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Immunology
Sweden
2026
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Medicine
Sweden
2023

D-Index & Metrics

Immunology

D-Index
118
Citations
46195
World Ranking
359
National Ranking
4

Medicine

D-Index
118
Citations
46216
World Ranking
4084
National Ranking
81

Research.com Recognitions

  • 2026 - Research.com Immunology in Sweden Leader Award
  • 2025 - Research.com Immunology in Sweden Leader Award
  • 2023 - Research.com Medicine in Sweden Leader Award
  • 2022 - Research.com Immunology in Sweden Leader Award
  • 2003 - Nordic Medical Prize, SalusAnsvar/Ulf Nilsonnes Foundation for Medical Research

Overview

Rikard Holmdahl is affiliated with the Karolinska Institute in Sweden, focusing primarily on research within Medicine and Immunology and Microbiology. Their work spans various subfields, including Immunology, Rheumatology, Molecular Biology, Radiology, Nuclear Medicine and Imaging, and Immunology and Allergy.

Their research explores key topics such as:

  • Monoclonal and Polyclonal Antibodies Research
  • Rheumatoid Arthritis Research and Therapies
  • T-cell and B-cell Immunology
  • Cell Adhesion Molecules Research
  • Immunotherapy and Immune Responses
  • Systemic Lupus Erythematosus Research
  • Immune Response and Inflammation

Recent publications reflect a focus on inflammatory arthritis, immune mechanisms, and infectious diseases. These include:

  • 'SMASH' recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models, 2021, Annals of the Rheumatic Diseases
  • Dependence of SARS-CoV-2 infection on cholesterol-rich lipid raft and endosomal acidification, 2021, Computational and Structural Biotechnology Journal
  • Presence of autoantibodies in "seronegative" rheumatoid arthritis associates with classical risk factors and high disease activity, 2020, Arthritis Research & Therapy
  • Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation, 2022, Science Advances
  • Recent advances on smart glycoconjugate vaccines in infections and cancer, 2021, FEBS Journal

Frequent coauthors contributing to the collaborative research effort include:

  • Erik Lönnblom
  • Bingze Xu
  • Inger Gjertsson
  • Roman A. Zubarev
  • Gonzalo Fernandez Lahore

The preferred publication venues for research output demonstrate a concentration in rheumatology and immunology journals and include:

  • Annals of the Rheumatic Diseases (11 publications)
  • Nature Communications (7 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • Frontiers in Immunology (6 publications)
  • Redox Biology (5 publications)

Rikard Holmdahl received the Nordic Medical Prize from SalusAnsvar/Ulf Nilsonnes Foundation for Medical Research in 2003, recognizing contributions within the medical research community.

Best Publications

  • Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

    Yumiko Imai;Keiji Kuba;Keiji Kuba;G. Greg Neely;Rubina Yaghubian-Malhami

  • Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

    Christine Schauer;Christina Janko;Luis E Munoz;Yi Zhao

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Positional identification of Ncf1 as a gene that regulates arthritis severity in rats.

    Peter Olofsson;Jens Holmberg;Jesper Tordsson;Shemin Lu

  • Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies.

    Rikard Holmdahl;Kristofer Rubin;Lars Klareskog;Erik Larsson

  • Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene

    Malin Hultqvist;Peter Olofsson;Jens Holmberg;B. Thomas Bäckström

  • B cell‐deficient mice do not develop type II collagen‐induced arthritis (CIA)

    L Svensson;J Jirholt;R Holmdahl;L Jansson

  • A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor.

    Lars S. Madsen;Ellen Christina Andersson;Liselotte Jansson;Michelle Krogsgaard

  • Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes.

    Kutty Selva Nandakumar;Lars Svensson;Rikard Holmdahl

  • Macrophage migration inhibitory factor is involved in the pathogenesis of collagen type II-induced arthritis in mice.

    A Mikulowska;C N Metz;R Bucala;R Holmdahl

  • Progress and prospects in rat genetics: a community view.

    Timothy J Aitman;John K Critser;Edwin Cuppen;Anna Dominiczak

  • Type II collagen autoimmunity in animals and provocations leading to arthritis.

    R. Holmdahl;M. Andersson;T. J. Goldschmidt;K. Gustafsson

  • Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable.

    Per Levéen;Jonas Larsson;Mats Ehinger;Corrado M. Cilio

  • Regulation of autoantibody activity by the IL-23-T H 17 axis determines the onset of autoimmune disease.

    René Pfeifle;Tobias Rothe;Natacha Ipseiz;Hans U Scherer

  • T cell surface redox levels determine T cell reactivity and arthritis susceptibility

    Kyra A. Gelderman;Malin Hultqvist;Jens Holmberg;Peter Olofsson

  • Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis

    Harald Burkhardt;Bettina Sehnert;Robert Bockermann;Åke Engström

  • Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis.

    Hüseyin Uysal;Robert Bockermann;Kutty S. Nandakumar;Kutty S. Nandakumar;Bettina Sehnert

  • Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

    Gustaf Wigerblad;Duygu B. Bas;Cátia Fernades-Cerqueira;Akilan Krishnamurthy

  • The protective role of ROS in autoimmune disease

    Malin Hultqvist;Lina M. Olsson;Kyra A. Gelderman;Kyra A. Gelderman;Rikard Holmdahl;Rikard Holmdahl

  • T lymphocytes in collagen II-induced arthritis in mice. Characterization of arthritogenic collagen II-specific T-cell lines and clones.

    R. Holmdahl;L. Klareskog;K. Rubin;E. Larsson

  • Predominant selection of T cells specific for the glycosylated collagen type II epitope (263–270) in humanized transgenic mice and in rheumatoid arthritis

    Johan Bäcklund;Stefan Carlsen;Torsten Höger;Björn Holm

Frequent Co-Authors

Lars Klareskog
Lars Klareskog Karolinska Institute
Kutty Selva Nandakumar
Kutty Selva Nandakumar Karolinska Institute
Jan Kihlberg
Jan Kihlberg Uppsala University
Tomas Olsson
Tomas Olsson Karolinska Institute
Johan Rönnelid
Johan Rönnelid Uppsala University
Vivianne Malmström
Vivianne Malmström Karolinska University Hospital
Kristofer Rubin
Kristofer Rubin Uppsala University
Åsa Johansson
Åsa Johansson Uppsala University
Per-Johan Jakobsson
Per-Johan Jakobsson Karolinska University Hospital
Ulf Pettersson
Ulf Pettersson Uppsala University

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