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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
16256
World Ranking
10658
National Ranking
151

Overview

Per-Johan Jakobsson is affiliated with Karolinska University Hospital in Sweden, contributing extensively to medical research. Their work spans multiple disciplines, primarily focusing on medicine and biochemistry, genetics, and molecular biology.

Jakobsson's research areas cover a variety of subfields including:

  • Rheumatology
  • Molecular Biology
  • Pharmacology
  • Immunology
  • Cancer Research

Their main research topics encompass:

  • Rheumatoid Arthritis Research and Therapies
  • Inflammatory mediators and NSAID effects
  • Systemic Lupus Erythematosus Research
  • Monoclonal and Polyclonal Antibodies Research
  • Autoimmune and Inflammatory Disorders Research
  • Inflammatory Myopathies and Dermatomyositis
  • Pharmacological Effects of Natural Compounds

Jakobsson has collaborated frequently with several co-authors, including:

  • Marina Korotkova
  • Helena Idborg
  • Runyue Huang
  • Ingrid E. Lundberg
  • Kaixin Gao

Their publications appear primarily in journals such as:

  • Frontiers in Pharmacology
  • Arthritis Research & Therapy
  • Journal of Autoimmunity
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology

Some of the recent papers by Per-Johan Jakobsson include:

  • "Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far?" (2022), published in Frontiers in Pharmacology
  • "Presence of autoantibodies in 'seronegative' rheumatoid arthritis associates with classical risk factors and high disease activity" (2020), published in Arthritis Research & Therapy
  • "Extracellular miR-574-5p Induces Osteoclast Differentiation via TLR 7/8 in Rheumatoid Arthritis" (2020), published in Frontiers in Immunology
  • "Where traditional Chinese medicine meets Western medicine in the prevention of rheumatoid arthritis" (2022), published in Journal of Internal Medicine
  • "An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products" (2020), published in Science Translational Medicine

Best Publications

  • Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

    Per-Johan Jakobsson;Staffan Thorén;Ralf Morgenstern;Bengt Samuelsson

  • Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

    Ulrike Harre;Dan Georgess;Holger Bang;Aline Bozec

  • Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target

    Bengt Samuelsson;Ralf Morgenstern;Per-Johan Jakobsson

  • Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase

    Catherine E. Trebino;Jeffrey L. Stock;Colleen P. Gibbons;Brian M. Naiman

  • Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis

    William L. Smith;Yoshihiro Urade;Per Johan Jakobsson

  • Inflammatory response: pathway across the blood-brain barrier.

    Monica Ek;David Engblom;Sipra Saha;Anders Blomqvist

  • Common structural features of MAPEG -- a widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolism.

    Per-Johan Jakobsson;Ralf Morgenstern;Joseph Mancini;Anthony Ford-Hutchinson

  • Metabolism of the Endocannabinoids, 2-Arachidonylglycerol and Anandamide, into Prostaglandin, Thromboxane, and Prostacyclin Glycerol Esters and Ethanolamides

    Kevin R. Kozak;Brenda C. Crews;Jason D. Morrow;Lee-Ho Wang

  • Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

    Akilan Krishnamurthy;Vijay Joshua;Aase Haj Hensvold;Tao Jin

  • Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells.

    Dirk O. Stichtenoth;Staffan Thorén;Huimin Bian;Marc Peters-Golden

  • Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis.

    David Engblom;Sipra Saha;Linda Engström;Marie Westman

  • Coordinate up‐ and down‐regulation of glutathione‐dependent prostaglandin E synthase and cyclooxygenase‐2 in A549 cells

    Staffan Thorén;Per-Johan Jakobsson

  • Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

    Gustaf Wigerblad;Duygu B. Bas;Cátia Fernades-Cerqueira;Akilan Krishnamurthy

  • Inducible Microsomal Prostaglandin E Synthase Is Overexpressed in Colorectal Adenomas and Cancer

    Kazuhiko Yoshimatsu;Dragan Golijanin;Philip B. Paty;Robert A. Soslow

  • MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

    Hanna Zirath;Anna Frenzel;Ganna Oliynyk;Lova Segerström

  • Inducible prostaglandin E synthase is overexpressed in non-small cell lung cancer.

    Kazuhiko Yoshimatsu;Nasser K. Altorki;Dragan Golijanin;Fan Zhang

  • Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily.

    Per-Johan Jakobsson;Ralf Morgenstern;Joseph Mancini;Anthony Ford-Hutchinson

  • Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis

    Mikael Brink;Monika Hansson;Linda Mathsson;Per-Johan Jakobsson

  • Human Microsomal Prostaglandin E Synthase-1 PURIFICATION, FUNCTIONAL CHARACTERIZATION, AND PROJECTION STRUCTURE DETERMINATION

    Staffan Thorén;Rolf Weinander;Sipra Saha;Caroline Jegerschöld

  • Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

    Aase Haj Hensvold;Patrik K E Magnusson;Vijay Joshua;Monika Hansson

Frequent Co-Authors

Lars Klareskog
Lars Klareskog Karolinska Institute
Anca I. Catrina
Anca I. Catrina Karolinska University Hospital
Johan Rönnelid
Johan Rönnelid Uppsala University
Ralf Morgenstern
Ralf Morgenstern Karolinska Institute
Rikard Holmdahl
Rikard Holmdahl Karolinska Institute
Vivianne Malmström
Vivianne Malmström Karolinska University Hospital
Iva Gunnarsson
Iva Gunnarsson Karolinska University Hospital
Janne Lehtiö
Janne Lehtiö Karolinska Institute
Ingrid E. Lundberg
Ingrid E. Lundberg Karolinska University Hospital
Elisabet Svenungsson
Elisabet Svenungsson Karolinska University Hospital

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